Fabrizio Manetti
Fabrizio Manetti
Associate Professor, University of Siena (Italy)
Verified email at unisi.it
Cited by
Cited by
MmpL3 is the cellular target of the antitubercular pyrrole derivative BM212
V La Rosa, G Poce, JO Canseco, S Buroni, MR Pasca, M Biava, RM Raju, ...
Antimicrobial agents and chemotherapy 56 (1), 324-331, 2012
Synthesis, biological evaluation, and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis: Part 2. Synthesis of rigid pyrazolones
D Castagnolo, F Manetti, M Radi, B Bechi, M Pagano, A De Logu, ...
Bioorganic & medicinal chemistry 17 (15), 5716-5721, 2009
Synthesis, Biological Evaluation, and Pharmacophore Generation of New Pyridazinone Derivatives with Affinity toward α1-and α2-Adrenoceptors 1
R Barbaro, L Betti, M Botta, F Corelli, G Giannaccini, L Maccari, F Manetti, ...
Journal of medicinal chemistry 44 (13), 2118-2132, 2001
Synthesis, biological evaluation and SAR study of novel pyrazole analogues as inhibitors of Mycobacterium tuberculosis
D Castagnolo, A De Logu, M Radi, B Bechi, F Manetti, M Magnani, ...
Bioorganic & medicinal chemistry 16 (18), 8587-8591, 2008
Antimycobacterial agents. Novel diarylpyrrole derivatives of BM212 endowed with high activity toward Mycobacterium tuberculosis and low cytotoxicity
M Biava, GC Porretta, G Poce, S Supino, D Deidda, R Pompei, P Molicotti, ...
Journal of medicinal chemistry 49 (16), 4946-4952, 2006
Fibroblast growth factors and their inhibitors
F Manetti, F Corelli, M Botta
Current pharmaceutical design 6 (18), 1897-1924, 2000
LIM kinases are attractive targets with many macromolecular partners and only a few small molecule regulators
F Manetti
Medicinal research reviews 32 (5), 968-998, 2012
Antifungal Agents. 10. New Derivatives of 1-[(Aryl)[4-aryl-1 H-pyrrol-3-yl] methyl]-1 H-imidazole, Synthesis, Anti-Candida Activity, and Quantitative Structure-Analysis …
A Tafi, R Costi, M Botta, R Di Santo, F Corelli, S Massa, A Ciacci, ...
Journal of medicinal chemistry 45 (13), 2720-2732, 2002
New pyrazolo [3, 4-d] pyrimidines endowed with A431 antiproliferative activity and inhibitory properties of Src phosphorylation
S Schenone, O Bruno, A Ranise, F Bondavalli, C Brullo, P Fossa, L Mosti, ...
Bioorganic & medicinal chemistry letters 14 (10), 2511-2517, 2004
Antimycobacterial compounds. New pyrrole derivatives of BM212
M Biava, GC Porretta, D Deidda, R Pompei, A Tafi, F Manetti
Bioorganic & medicinal chemistry 12 (6), 1453-1458, 2004
Pyrazolo [3, 4-d] pyrimidines as potent antiproliferative and proapoptotic agents toward A431 and 8701-BC cells in culture via inhibition of c-Src phosphorylation
F Carraro, A Naldini, A Pucci, GA Locatelli, G Maga, S Schenone, O Bruno, ...
Journal of medicinal chemistry 49 (5), 1549-1561, 2006
Computational comparison of microtubule-stabilising agents laulimalide and peloruside with taxol and colchicine
O Pineda, J Farrąs, L Maccari, F Manetti, M Botta, J Vilarrasa
Bioorganic & medicinal chemistry letters 14 (19), 4825-4829, 2004
Importance of the thiomorpholine introduction in new pyrrole derivatives as antimycobacterial agents analogues of BM 212
M Biava, GC Porretta, D Deidda, R Pompei, A Tafi, F Manetti
Bioorganic & medicinal chemistry 11 (4), 515-520, 2003
Structure-based optimization of pyrazolo [3, 4-d] pyrimidines as Abl inhibitors and antiproliferative agents toward human leukemia cell lines
F Manetti, C Brullo, M Magnani, F Mosci, B Chelli, E Crespan, ...
Journal of medicinal chemistry 51 (5), 1252-1259, 2008
Pharmacophore Modeling and Molecular Docking Led to the Discovery of Inhibitors of Human Immunodeficiency Virus-1 Replication Targeting the Human Cellular Aspartic Acid …
G Maga, F Falchi, A Garbelli, A Belfiore, M Witvrouw, F Manetti, M Botta
Journal of medicinal chemistry 51 (21), 6635-6638, 2008
1, 5-Diphenylpyrrole derivatives as antimycobacterial agents. Probing the influence on antimycobacterial activity of lipophilic substituents at the phenyl rings
M Biava, GC Porretta, G Poce, A De Logu, M Saddi, R Meleddu, F Manetti, ...
Journal of medicinal chemistry 51 (12), 3644-3648, 2008
Identification of a Novel Pyrazolo[3,4-d]pyrimidine Able To Inhibit Cell Proliferation of a Human Osteogenic Sarcoma in Vitro and in a Xenograft Model in Mice
F Manetti, A Santucci, GA Locatelli, G Maga, A Spreafico, T Serchi, ...
Journal of medicinal chemistry 50 (23), 5579-5588, 2007
Synthesis, biological evaluation and docking studies of 4-amino substituted 1H-pyrazolo [3, 4-d] pyrimidines
S Schenone, C Brullo, O Bruno, F Bondavalli, L Mosti, G Maga, E Crespan, ...
European journal of medicinal chemistry 43 (12), 2665-2676, 2008
Acylthiourea, acylurea, and acylguanidine derivatives with potent hedgehog inhibiting activity
A Solinas, H Faure, H Roudaut, E Traiffort, A Schoenfelder, A Mann, ...
Journal of medicinal chemistry 55 (4), 1559-1571, 2012
Improved BM212 MmpL3 inhibitor analogue shows efficacy in acute murine model of tuberculosis infection
G Poce, RH Bates, S Alfonso, M Cocozza, GC Porretta, L Ballell, J Rullas, ...
PLoS One 8 (2), e56980, 2013
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