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kostas vekrellis
kostas vekrellis
BIOMEDICAL RESEARCH FOUNDATION ACADEMY OF ATHENS, Research Director, Center for
Verified email at bioacademy.gr
Title
Cited by
Cited by
Year
Cell-produced α-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival
E Emmanouilidou, K Melachroinou, T Roumeliotis, SD Garbis, M Ntzouni, ...
Journal of Neuroscience 30 (20), 6838-6851, 2010
12332010
Wild type α-synuclein is degraded by chaperone-mediated autophagy and macroautophagy in neuronal cells
T Vogiatzi, M Xilouri, K Vekrellis, L Stefanis
Journal of Biological Chemistry 283 (35), 23542-23556, 2008
7542008
Pathological roles of α-synuclein in neurological disorders
K Vekrellis, M Xilouri, E Emmanouilidou, HJ Rideout, L Stefanis
The Lancet Neurology 10 (11), 1015-1025, 2011
4602011
Abberant α-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy
M Xilouri, T Vogiatzi, K Vekrellis, D Park, L Stefanis
PloS one 4 (5), e5515, 2009
4112009
ER stress and autophagic perturbations lead to elevated extracellular α-synuclein in GBA-N370S Parkinson's iPSC-derived dopamine neurons
HJR Fernandes, EM Hartfield, HC Christian, E Emmanoulidou, Y Zheng, ...
Stem cell reports 6 (3), 342-356, 2016
3542016
Cell-produced α-synuclein oligomers are targeted to, and impair, the 26S proteasome
E Emmanouilidou, L Stefanis, K Vekrellis
Neurobiology of aging 31 (6), 953-968, 2010
2682010
Tsc1 (hamartin) confers neuroprotection against ischemia by inducing autophagy
M Papadakis, G Hadley, M Xilouri, LC Hoyte, S Nagel, MM McMenamin, ...
Nature medicine 19 (3), 351-357, 2013
2352013
Autophagy inhibition promotes SNCA/alpha-synuclein release and transfer via extracellular vesicles with a hybrid autophagosome-exosome-like phenotype
G Minakaki, S Menges, A Kittel, E Emmanouilidou, I Schaeffner, ...
Autophagy 14 (1), 98-119, 2018
2292018
Assessment of α-synuclein secretion in mouse and human brain parenchyma
E Emmanouilidou, D Elenis, T Papasilekas, G Stranjalis, K Gerozissis, ...
PloS one 6 (7), e22225, 2011
1782011
How is alpha‐synuclein cleared from the cell?
L Stefanis, E Emmanouilidou, M Pantazopoulou, D Kirik, K Vekrellis, ...
Journal of neurochemistry 150 (5), 577-590, 2019
1652019
Phosphorylated exogenous alpha-synuclein fibrils exacerbate pathology and induce neuronal dysfunction in mice
M Karampetsou, MT Ardah, M Semitekolou, A Polissidis, M Samiotaki, ...
Scientific reports 7 (1), 16533, 2017
1542017
Defective synaptic connectivity and axonal neuropathology in a human iPSC-based model of familial Parkinson’s disease
G Kouroupi, E Taoufik, IS Vlachos, K Tsioras, N Antoniou, ...
Proceedings of the National Academy of Sciences 114 (18), E3679-E3688, 2017
1462017
Inducible over‐expression of wild type α‐synuclein in human neuronal cells leads to caspase‐dependent non‐apoptotic death
K Vekrellis, M Xilouri, E Emmanouilidou, L Stefanis
Journal of neurochemistry 109 (5), 1348-1362, 2009
1382009
Neurobiology of α-synuclein
K Vekrellis, HJ Rideout, L Stefanis
Molecular neurobiology 30, 1-21, 2004
1372004
Extracellular progranulin protects cortical neurons from toxic insults by activating survival signaling
J Xu, M Xilouri, J Bruban, J Shioi, Z Shao, I Papazoglou, K Vekrellis, ...
Neurobiology of aging 32 (12), 2326. e5-2326. e16, 2011
1142011
Modeling alpha-synuclein pathology in a human brain-chip to assess blood-brain barrier disruption
I Pediaditakis, KR Kodella, DV Manatakis, CY Le, CD Hinojosa, ...
Nature communications 12 (1), 5907, 2021
1092021
Cellular models of alpha‐synuclein toxicity and aggregation
M Delenclos, JD Burgess, A Lamprokostopoulou, TF Outeiro, K Vekrellis, ...
Journal of neurochemistry 150 (5), 566-576, 2019
1002019
Modulation of β-glucocerebrosidase increases α-synuclein secretion and exosome release in mouse models of Parkinson’s disease
VE Papadopoulos, G Nikolopoulou, I Antoniadou, A Karachaliou, ...
Human molecular genetics 27 (10), 1696-1710, 2018
982018
Alpha-synuclein research: defining strategic moves in the battle against Parkinson’s disease
LMA Oliveira, T Gasser, R Edwards, M Zweckstetter, R Melki, L Stefanis, ...
npj Parkinson's Disease 7 (1), 65, 2021
972021
The small GTPase Rab11 co-localizes with α-synuclein in intracellular inclusions and modulates its aggregation, secretion and toxicity
O Chutna, S Gonçalves, A Villar-Piqué, P Guerreiro, Z Marijanovic, ...
Human molecular genetics 23 (25), 6732-6745, 2014
952014
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