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MANUEL PERUCHO
MANUEL PERUCHO
Professor emeritus
Verified email at sbpdiscovery.org
Title
Cited by
Cited by
Year
Ubiquitous somatic mutations in simple repeated sequences reveal a new mechanism for colonic carcinogenesis
Y Ionov, MA Peinado, S Malkhosyan, D Shibata, M Perucho
Nature 363 (6429), 558-561, 1993
34431993
Most human carcinomas of the exocrine pancreas contain mutant cK-ras genes
C Almoguera, D Shibata, K Forrester, J Martin, N Arnheim, M Perucho
Cell 53 (4), 549-554, 1988
28041988
Somatic frameshift mutations in the BAX gene in colon cancers of the microsatellite mutator phenotype
N Rampino, H Yamamoto, Y Ionov, Y Li, H Sawai, JC Reed, M Perucho
Science 275 (5302), 967-969, 1997
17911997
Detection of high incidence of K-ras oncogenes during human colon tumorigenesis
K Forrester, C Almoguera, K Han, WE Grizzle, M Perucho
Nature 327 (6120), 298-303, 1987
14221987
A National Cancer Institute workshop on hereditary nonpolyposis colorectal cancer syndrome: meeting highlights and Bethesda guidelines
MA Rodriguez-Bigas, CR Boland, SR Hamilton, DE Henson, S Srivastava, ...
Journal of the National Cancer Institute 89 (23), 1758-1762, 1997
14121997
Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells
M Goldfarb, K Shimizu, M Perucho, M Wigler
Nature 296 (5856), 404-409, 1982
6521982
Genomic instability in repeated sequences is an early somatic event in colorectal tumorigenesis that persists after transformation
D Shibata, MA Peinado, Y lonov, S Malkhosyan, M Perucho
Nature genetics 6 (3), 273-281, 1994
6211994
Human-tumor-derived cell lines contain common and different transforming genes
M Perucho, M Goldfarb, K Shimizu, C Lama, J Fogh, M Wigler
Cell 27 (3), 467-476, 1981
5931981
Three human transforming genes are related to the viral ras oncogenes.
K Shimizu, M Goldfarb, Y Suard, M Perucho, Y Li, T Kamata, J Feramisco, ...
Proceedings of the National Academy of Sciences 80 (8), 2112-2116, 1983
5421983
Genetic and physical linkage of exogenous sequences in transformed cells
M Perucho, D Hanahan, M Wigler
Cell 22 (1), 309-317, 1980
5251980
The somatic replication of DNA methylation
M Wigler, D Levy, M Perucho
Cell 24 (1), 33-40, 1981
4891981
A method to detect and characterize point mutations in transcribed genes: amplification and overexpression of the mutant c-Ki-ras allele in human tumor cells.
E Winter, F Yamamoto, C Almoguera, M Perucho
Proceedings of the National Academy of Sciences 82 (22), 7575-7579, 1985
4431985
Isolation and preliminary characterization of the transforming gene of a human neuroblastoma cell line.
K Shimizu, M Goldfarb, M Perucho, M Wigler
Proceedings of the National Academy of Sciences 80 (2), 383-387, 1983
4131983
Frameshift mutator mutations
S Malkhosyan, N Rampino, H Yamamoto, M Perucho
Nature 382 (6591), 499-500, 1996
3981996
Isolation and characterization of allelic losses and gains in colorectal tumors by arbitrarily primed polymerase chain reaction.
MA Peinado, S Malkhosyan, A Velazquez, M Perucho
Proceedings of the National Academy of Sciences 89 (21), 10065-10069, 1992
3981992
Defective mismatch repair in extracts of colorectal and endometrial cancer cell lines exhibiting microsatellite instability.
A Umar, JC Boyer, DC Thomas, DC Nguyen, JI Risinger, J Boyd, Y Ionov, ...
Journal of Biological Chemistry 269 (20), 14367-14370, 1994
3901994
Cancer of the microsatellite mutator phenotype
M Perucho
BIOLOGICAL CHEMISTRY HOPPE SEYLER 377, 675-684, 1996
3511996
Frameshift somatic mutations in gastrointestinal cancer of the microsatellite mutator phenotype
H Yamamoto, H Sawai, M Perucho
Cancer research 57 (19), 4420-4426, 1997
3291997
Global DNA demethylation in gastrointestinal cancer is age dependent and precedes genomic damage
K Suzuki, I Suzuki, A Leodolter, S Alonso, S Horiuchi, K Yamashita, ...
Cancer cell 9 (3), 199-207, 2006
3242006
Frameshift Mutations at Mononucleotide Repeats in caspase-5 and Other Target Genes in Endometrial and Gastrointestinal Cancer of the Microsatellite Mutator …
S Schwartz Jr, H Yamamoto, M Navarro, M Maestro, J Reventós, ...
Cancer research 59 (12), 2995-3002, 1999
3181999
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