Richard LeDuc
Richard LeDuc
Director of Computational Proteomics, Proteomics Center of Excellence, Northwestern University
Verified email at northwestern.edu
TitleCited byYear
De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis
BJ Haas, A Papanicolaou, M Yassour, M Grabherr, PD Blood, J Bowden, ...
Nature Protocols 8 (8), 1494-1512, 2013
36672013
Mapping intact protein isoforms in discovery mode using top-down proteomics
JC Tran, L Zamdborg, DR Ahlf, JE Lee, AD Catherman, KR Durbin, ...
Nature 480 (7376), 254-258, 2011
5612011
ProSight PTM 2.0: improved protein identification and characterization for top down mass spectrometry
L Zamdborg, RD LeDuc, KJ Glowacz, YB Kim, V Viswanathan, ...
Nucleic acids research 35 (suppl 2), W701-W706, 2007
2222007
ProSight PTM: an integrated environment for protein identification and characterization by top-down mass spectrometry
RD LeDuc, GK Taylor, YB Kim, TE Januszyk, LH Bynum, JV Sola, ...
Nucleic acids research 32 (suppl 2), W340-W345, 2004
1952004
Combinatorial modification of human histone H4 quantitated by two-dimensional liquid chromatography coupled with top down mass spectrometry
JJ Pesavento, CR Bullock, RD LeDuc, CA Mizzen, NL Kelleher
Journal of Biological Chemistry 283 (22), 14927-14937, 2008
1652008
ProSight Lite: Graphical software to analyze top‐down mass spectrometry data
RT Fellers, JB Greer, BP Early, X Yu, RD LeDuc, NL Kelleher, PM Thomas
Proteomics 15 (7), 1235-1238, 2015
1262015
Applying label-free quantitation to top down proteomics
I Ntai, K Kim, RT Fellers, OS Skinner, AD Smith IV, BP Early, JP Savaryn, ...
Analytical chemistry 86 (10), 4961-4968, 2014
752014
New and automated MS n approaches for top-down identification of modified proteins
V Zabrouskov, MW Senko, Y Du, RD Leduc, NL Kelleher
Journal of the American Society for Mass Spectrometry 16 (12), 2027-2038, 2005
752005
The first pilot project of the consortium for top‐down proteomics: A status report
X Dang, J Scotcher, S Wu, RK Chu, N Tolić, I Ntai, PM Thomas, RT Fellers, ...
Proteomics 14 (10), 1130-1140, 2014
742014
Revealing novel telomere proteins using in vivo cross-linking, tandem affinity purification, and label-free quantitative LC-FTICR-MS
T Nittis, L Guittat, RD LeDuc, B Dao, JP Duxin, H Rohrs, RR Townsend, ...
Molecular & Cellular Proteomics 9 (6), 1144-1156, 2010
542010
ESTIMA, a tool for EST management in a multi-project environment
CG Kumar, R LeDuc, G Gong, L Roinishivili, HA Lewin, L Liu
BMC bioinformatics 5 (1), 176, 2004
542004
The C-score: a Bayesian framework to sharply improve proteoform scoring in high-throughput top down proteomics
RD LeDuc, RT Fellers, BP Early, JB Greer, PM Thomas, NL Kelleher
Journal of proteome research 13 (7), 3231-3240, 2014
532014
High-throughput analysis of intact human proteins using UVPD and HCD on an Orbitrap mass spectrometer
TP Cleland, CJ DeHart, RT Fellers, AJ VanNispen, JB Greer, RD LeDuc, ...
Journal of Proteome Research 16 (5), 2072-2079, 2017
482017
Integrated bottom-up and top-down proteomics of patient-derived breast tumor xenografts
I Ntai, RD LeDuc, RT Fellers, P Erdmann-Gilmore, SR Davies, J Rumsey, ...
Molecular & Cellular Proteomics 15 (1), 45-56, 2016
472016
Trinity RNA-Seq assembler performance optimization
R Henschel, M Lieber, LS Wu, PM Nista, BJ Haas, RD LeDuc
Proceedings of the 1st Conference of the Extreme Science and Engineering …, 2012
462012
Identification and characterization of human proteoforms by top-down LC-21 tesla FT-ICR mass spectrometry
LC Anderson, CJ DeHart, NK Kaiser, RT Fellers, DF Smith, JB Greer, ...
Journal of proteome research 16 (2), 1087-1096, 2017
452017
An informatic framework for decoding protein complexes by top-down mass spectrometry
OS Skinner, PC Havugimana, NA Haverland, L Fornelli, BP Early, ...
Nature methods 13 (3), 237-240, 2016
432016
Using ProSight PTM and related tools for targeted protein identification and characterization with high mass accuracy tandem MS data
RD LeDuc, NL Kelleher
Curr. Protoc. Bioinformatics, 13.6, 2007
422007
Advancing top-down analysis of the human proteome using a benchtop quadrupole-Orbitrap mass spectrometer
L Fornelli, KR Durbin, RT Fellers, BP Early, JB Greer, RD LeDuc, ...
Journal of Proteome Research 16 (2), 609-618, 2016
402016
Diversity of Amyloid-beta Proteoforms in the Alzheimer's Disease Brain.
NC Wildburger, TJ Esparza, RD LeDuc, RT Fellers, PM Thomas, ...
Scientific reports 7 (1), 9520, 2017
392017
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