Matthew A Nugent
Matthew A Nugent
Associate Dean for Research, Innovation and Partnerships, Professor of Biological Sciences
Verified email at - Homepage
TitleCited byYear
Fibroblast growth factor-2
MA Nugent, RV Iozzo
The international journal of biochemistry & cell biology 32 (2), 115-120, 2000
Mechanisms of venous leakage: a prospective clinicopathological correlation of corporeal function and structure
A Nehra, I Goldstein, A Pabby, M Nugent, YH Huang, A de las Morenas, ...
The Journal of urology 156 (4), 1320-1329, 1996
Perivascular and intravenous administration of basic fibroblast growth factor: vascular and solid organ deposition.
ER Edelman, MA Nugent, MJ Karnovsky
Proceedings of the National Academy of Sciences 90 (4), 1513-1517, 1993
Basic fibroblast growth factor enhances the coupling of intimal hyperplasia and proliferation of vasa vasorum in injured rat arteries.
ER Edelman, MA Nugent, LT Smith, MJ Karnovsky
The Journal of clinical investigation 89 (2), 465-473, 1992
Kinetics of basic fibroblast growth factor binding to its receptor and heparan sulfate proteoglycan: a mechanism for cooperativity
MA Nugent, ER Edelman
Biochemistry 31 (37), 8876-8883, 1992
Sustained down-regulation of the epidermal growth factor receptor by decorin a mechanism for controlling tumor growth in vivo
G Csordás, M Santra, CC Reed, I Eichstetter, DJ McQuillan, D Gross, ...
Journal of Biological Chemistry 275 (42), 32879-32887, 2000
Antisense targeting of perlecan blocks tumor growth and angiogenesis in vivo.
B Sharma, M Handler, I Eichstetter, JM Whitelock, MA Nugent, RV Iozzo
The Journal of clinical investigation 102 (8), 1599-1608, 1998
Heparan sulfate mediates bFGF transport through basement membrane by diffusion with rapid reversible binding
CJ Dowd, CL Cooney, MA Nugent
Journal of Biological Chemistry 274 (8), 5236-5244, 1999
Potentiation and inhibition of bFGF binding by heparin: a model for regulation of cellular response
M Fannon, KE Forsten, MA Nugent
Biochemistry 39 (6), 1434-1445, 2000
Heparinase inhibits neovascularization.
R Sasisekharan, MA Moses, MA Nugent, CL Cooney, R Langer
Proceedings of the National Academy of Sciences 91 (4), 1524-1528, 1994
Perlecan is required to inhibit thrombosis after deep vascular injury and contributes to endothelial cell-mediated inhibition of intimal hyperplasia
MA Nugent, HM Nugent, RV Iozzo, K Sanchack, ER Edelman
Proceedings of the National Academy of Sciences 97 (12), 6722-6727, 2000
Basic fibroblast growth factor binds its receptors, is internalized, and stimulates DNA synthesis in Balb/c3T3 cells in the absence of heparan sulfate
M Fannon, MA Nugent
Journal of Biological Chemistry 271 (30), 17949-17956, 1996
Heparan sulfate proteoglycans control intracellular processing of bFGF in vascular smooth muscle cells
GV Sperinde, MA Nugent
Biochemistry 37 (38), 13153-13164, 1998
Heparan sulfate–FGF10 interactions during lung morphogenesis
KI Izvolsky, D Shoykhet, Y Yang, Q Yu, MA Nugent, WV Cardoso
Developmental biology 258 (1), 185-200, 2003
Heparan sulfate proteoglycans function as receptors for fibroblast growth factor-2 activation of extracellular signal–regulated kinases 1 and 2
CC Chua, N Rahimi, K Forsten-Williams, MA Nugent
Circulation research 94 (3), 316-323, 2004
pH regulates vascular endothelial growth factor binding to fibronectin a mechanism for control of extracellular matrix storage and release
AL Goerges, MA Nugent
Journal of Biological Chemistry 279 (3), 2307-2315, 2004
Tissue engineered perivascular endothelial cell implants regulate vascular injury
A Nathan, MA Nugent, ER Edelman
Proceedings of the National Academy of Sciences 92 (18), 8130-8134, 1995
Vascular cell-derived heparan sulfate shows coupled inhibition of basic fibroblast growth factor binding and mitogenesis in vascular smooth muscle cells.
MA Nugent, MJ Karnovsky, ER Edelman
Circulation research 73 (6), 1051-1060, 1993
Heparin-mediated conformational changes in fibronectin expose vascular endothelial growth factor binding sites
M Mitsi, Z Hong, CE Costello, MA Nugent
Biochemistry 45 (34), 10319-10328, 2006
Nuclear localization of basic fibroblast growth factor is mediated by heparan sulfate proteoglycans through protein kinase C signaling
E Hsia, TP Richardson, MA Nugent
Journal of cellular biochemistry 88 (6), 1214-1225, 2003
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