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Rachel Queen
Rachel Queen
Verified email at newcastle.ac.uk
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SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes
W Sungnak, N Huang, C Bécavin, M Berg, R Queen, M Litvinukova, ...
Nature medicine 26 (5), 681-687, 2020
26952020
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics
C Muus, MD Luecken, G Eraslan, L Sikkema, A Waghray, G Heimberg, ...
Nature medicine 27 (3), 546-559, 2021
2952021
Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and …
C Muus, MD Luecken, G Eraslan, A Waghray, G Heimberg, L Sikkema, ...
BioRxiv, 2020.04. 19.049254, 2020
2552020
Transcriptomic profiling across the nonalcoholic fatty liver disease spectrum reveals gene signatures for steatohepatitis and fibrosis
O Govaere, S Cockell, D Tiniakos, R Queen, R Younes, M Vacca, ...
Science translational medicine 12 (572), eaba4448, 2020
2192020
Differential IRF8 transcription factor requirement defines two pathways of dendritic cell development in humans
U Cytlak, A Resteu, S Pagan, K Green, P Milne, S Maisuria, D McDonald, ...
Immunity 53 (2), 353-370. e8, 2020
1702020
Co-expression of SARS-CoV-2 entry genes in the superficial adult human conjunctival, limbal and corneal epithelium suggests an additional route of entry via the ocular surface
J Collin, R Queen, D Zerti, B Dorgau, M Georgiou, I Djidrovski, R Hussain, ...
The ocular surface 19, 190-200, 2021
1382021
Deconstructing retinal organoids: single cell RNA-Seq reveals the cellular components of human pluripotent stem cell-derived retina
J Collin, R Queen, D Zerti, B Dorgau, R Hussain, J Coxhead, S Cockell, ...
Stem Cells 37 (5), 593-598, 2019
1062019
A single cell atlas of human cornea that defines its development, limbal progenitor cells and their interactions with the immune cells
J Collin, R Queen, D Zerti, S Bojic, B Dorgau, N Moyse, MM Molina, ...
The ocular surface 21, 279-298, 2021
1052021
HCA Lung Biological Network
W Sungnak, N Huang, C Bécavin, M Berg, R Queen, M Litvinukova, ...
SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells …, 2020
822020
Systematic comparison of retinal organoid differentiation from human pluripotent stem cells reveals stage specific, cell line, and methodological differences
CB Mellough, J Collin, R Queen, G Hilgen, B Dorgau, D Zerti, ...
Stem cells translational medicine 8 (7), 694-706, 2019
812019
Blood and immune development in human fetal bone marrow and Down syndrome
L Jardine, S Webb, I Goh, M Quiroga Londoño, G Reynolds, M Mather, ...
Nature 598 (7880), 327-331, 2021
772021
CRX expression in pluripotent stem cell-derived photoreceptors marks a transplantable subpopulation of early cones
J Collin, D Zerti, R Queen, T Santos-Ferreira, R Bauer, J Coxhead, ...
Stem Cells 37 (5), 609-622, 2019
632019
In the eye of the storm: SARS-CoV-2 infection and replication at the ocular surface?
L Armstrong, J Collin, I Mostafa, R Queen, FC Figueiredo, M Lako
Stem Cells Translational Medicine 10 (7), 976-986, 2021
362021
Increased serum miR-193a-5p during non-alcoholic fatty liver disease progression: Diagnostic and mechanistic relevance
K Johnson, PJ Leary, O Govaere, MJ Barter, SH Charlton, SJ Cockell, ...
JHEP Reports 4 (2), 100409, 2022
322022
CD200 expression marks a population of quiescent limbal epithelial stem cells with holoclone forming ability
S Bojic, D Hallam, N Alcada, A Ghareeb, R Queen, S Pervinder, H Buck, ...
Stem Cells 36 (11), 1723-1735, 2018
282018
Understanding the complexity of retina and pluripotent stem cell derived retinal organoids with single cell RNA sequencing: current progress, remaining challenges and future …
D Zerti, J Collin, R Queen, SJ Cockell, M Lako
Current eye research 45 (3), 385-396, 2020
232020
Mitochondrial DNA sequence context in the penetrance of mitochondrial t-RNA mutations: a study across multiple lineages with diagnostic implications
RA Queen, JS Steyn, P Lord, JL Elson
PLoS One 12 (11), e0187862, 2017
222017
Dissecting the transcriptional and chromatin accessibility heterogeneity of proliferating cone precursors in human retinoblastoma tumors by single cell sequencing—opening …
J Collin, R Queen, D Zerti, DH Steel, C Bowen, M Parulekar, M Lako
Investigative ophthalmology & visual science 62 (6), 18-18, 2021
212021
pRB-depleted pluripotent stem cell retinal organoids recapitulate cell state transitions of retinoblastoma development and suggest an important role for pRB in retinal cell …
A Rozanska, R Cerna-Chavez, R Queen, J Collin, D Zerti, B Dorgau, ...
Stem Cells Translational Medicine 11 (4), 415-433, 2022
192022
Human retinal organoids provide a suitable tool for toxicological investigations: a comprehensive validation using drugs and compounds affecting the retina
B Dorgau, M Georgiou, A Chaudhary, M Moya-Molina, J Collin, R Queen, ...
Stem Cells Translational Medicine 11 (2), 159-177, 2022
192022
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