|pH sensing and regulation in cancer|
M Damaghi, JW Wojtkowiak, RJ Gillies
Frontiers in physiology 4, 370, 2013
|Neutralization of tumor acidity improves antitumor responses to immunotherapy|
S Pilon-Thomas, KN Kodumudi, AE El-Kenawi, S Russell, AM Weber, ...
Cancer research 76 (6), 1381-1390, 2016
|Systems analysis of intracellular pH vulnerabilities for cancer therapy|
E Persi, M Duran-Frigola, M Damaghi, WR Roush, P Aloy, JL Cleveland, ...
Nature communications 9 (1), 1-11, 2018
|Chronic acidosis in the tumour microenvironment selects for overexpression of LAMP2 in the plasma membrane|
M Damaghi, NK Tafreshi, MC Lloyd, R Sprung, V Estrella, JW Wojtkowiak, ...
Nature communications 6 (1), 1-13, 2015
|Defining cancer subpopulations by adaptive strategies rather than molecular properties provides novel insights into intratumoral evolution|
A Ibrahim-Hashim, M Robertson-Tessi, PM Enriquez-Navas, M Damaghi, ...
Cancer research 77 (9), 2242-2254, 2017
|Causes, consequences, and therapy of tumors acidosis|
SR Pillai, M Damaghi, Y Marunaka, EP Spugnini, S Fais, RJ Gillies
Cancer and Metastasis Reviews 38 (1), 205-222, 2019
|Dendrosomes as novel gene porters‐III|
M Sadeghizadeh, B Ranjbar, M Damaghi, L Khaki, MN Sarbolouki, ...
Journal of Chemical Technology & Biotechnology: International Research in …, 2008
|pH-dependent interactions guide the folding and gate the transmembrane pore of the β-barrel membrane protein OmpG|
M Damaghi, C Bippes, S Köster, Ö Yildiz, SA Mari, W Kühlbrandt, ...
Journal of molecular biology 397 (4), 878-882, 2010
|One β Hairpin after the Other: Exploring Mechanical Unfolding Pathways of the Transmembrane β‐Barrel Protein OmpG|
KT Sapra, M Damaghi, S Köster, Ö Yildiz, W Kühlbrandt, DJ Muller
Angewandte Chemie 121 (44), 8456-8458, 2009
|Phenotypic changes of acid-adapted cancer cells push them toward aggressiveness in their evolution in the tumor microenvironment|
M Damaghi, R Gillies
Cell Cycle 16 (19), 1739-1743, 2017
|One β Hairpin Follows the Other: Exploring Refolding Pathways and Kinetics of the Transmembrane β‐Barrel Protein OmpG|
M Damaghi, S Köster, CA Bippes, Ö Yildiz, DJ Müller
Angewandte Chemie 123 (32), 7560-7562, 2011
|Dual energy landscape: The functional state of the β‐barrel outer membrane protein G molds its unfolding energy landscape|
M Damaghi, KT Sapra, S Köster, Ö Yildiz, W Kühlbrandt, DJ Muller
Proteomics 10 (23), 4151-4162, 2010
|Combining radiomics and mathematical modeling to elucidate mechanisms of resistance to immune checkpoint blockade in non-small cell lung cancer|
D Saeed-Vafa, R Bravo, JA Dean, A El-Kenawi, NM Père, M Strobl, ...
BioRxiv, 190561, 2017
|Integrative analysis of breast cancer cells reveals an epithelial-mesenchymal transition role in adaptation to acidic microenvironment|
M Sadeghi, B Ordway, I Rafiei, P Borad, B Fang, JL Koomen, C Zhang, ...
Frontiers in oncology 10, 304, 2020
|T-cells produce acidic niches in lymph nodes to suppress their own effector functions|
H Wu, V Estrella, M Beatty, D Abrahams, A El-Kenawi, S Russell, ...
Nature communications 11 (1), 1-13, 2020
|Lysosomal protein relocation as an adaptation mechanism to extracellular acidosis|
M Damaghi, RJ Gillies
Cell Cycle 15 (13), 1659, 2016
|Turnover modulates the need for a cost of resistance in adaptive therapy|
MAR Strobl, J West, Y Viossat, M Damaghi, M Robertson-Tessi, JS Brown, ...
Cancer Research 81 (4), 1135-1147, 2021
|Mix and match: phenotypic coexistence as a key facilitator of cancer invasion|
MAR Strobl, AL Krause, M Damaghi, R Gillies, ARA Anderson, PK Maini
Bulletin of mathematical biology 82 (1), 1-26, 2020
|Lymph nodes inhibit T-cell effector functions locally by establishing acidic niches|
H Wu, V Estrella, P Enriquez-Navas, A El-Kenawi, S Russell, D Abrahams, ...
BioRxiv, 689604, 2019
|Frequency-dependent interactions determine outcome of competition between two breast cancer cell lines|
AR Freischel, M Damaghi, JJ Cunningham, A Ibrahim-Hashim, RJ Gillies, ...