| Classification and mutation prediction from non–small cell lung cancer histopathology images using deep learning N Coudray, PS Ocampo, T Sakellaropoulos, N Narula, M Snuderl, ... Nature medicine 24 (10), 1559-1567, 2018 | 1985 | 2018 |
| DNA methylation-based classification of central nervous system tumours D Capper, DTW Jones, M Sill, V Hovestadt, D Schrimpf, D Sturm, ... Nature 555 (7697), 469-474, 2018 | 1934 | 2018 |
| Dynamic changes in the human methylome during differentiation L Laurent, E Wong, G Li, T Huynh, A Tsirigos, CT Ong, HM Low, ... Genome research 20 (3), 320-331, 2010 | 1195 | 2010 |
| Ketones and lactate “fuel” tumor growth and metastasis: Evidence that epithelial cancer cells use oxidative mitochondrial metabolism G Bonuccelli, A Tsirigos, D Whitaker-Menezes, S Pavlides, RG Pestell, ... Cell cycle 9 (17), 3506-3514, 2010 | 654 | 2010 |
| The bone marrow microenvironment at single-cell resolution AN Tikhonova, I Dolgalev, H Hu, KK Sivaraj, E Hoxha, ... Nature 569 (7755), 222-228, 2019 | 634 | 2019 |
| Accurate phylogenetic classification of variable-length DNA fragments AC McHardy, HG Martín, A Tsirigos, P Hugenholtz, I Rigoutsos Nature methods 4 (1), 63-72, 2007 | 589 | 2007 |
| Restoration of TET2 function blocks aberrant self-renewal and leukemia progression L Cimmino, I Dolgalev, Y Wang, A Yoshimi, GH Martin, J Wang, V Ng, ... Cell 170 (6), 1079-1095. e20, 2017 | 577 | 2017 |
| Genetic inactivation of the polycomb repressive complex 2 in T cell acute lymphoblastic leukemia P Ntziachristos, A Tsirigos, PV Vlierberghe, J Nedjic, T Trimarchi, ... Nature medicine 18 (2), 298-302, 2012 | 547 | 2012 |
| Genome-wide mapping and characterization of Notch-regulated long noncoding RNAs in acute leukemia T Trimarchi, E Bilal, P Ntziachristos, G Fabbri, R Dalla-Favera, A Tsirigos, ... Cell 158 (3), 593-606, 2014 | 455 | 2014 |
| Ketones and lactate increase cancer cell “stemness,” driving recurrence, metastasis and poor clinical outcome in breast cancer: achieving personalized medicine via Metabolo … UE Martinez-Outschoorn, M Prisco, A Ertel, A Tsirigos, Z Lin, S Pavlides, ... Cell cycle 10 (8), 1271-1286, 2011 | 379 | 2011 |
| Nrf2 activation promotes lung cancer metastasis by inhibiting the degradation of Bach1 L Lignitto, SE LeBoeuf, H Homer, S Jiang, M Askenazi, TR Karakousi, ... Cell 178 (2), 316-329. e18, 2019 | 367 | 2019 |
| Multipath routing in the presence of frequent topological changes A Tsirigos, ZJ Haas IEEE Communications Magazine 39 (11), 132-138, 2001 | 367 | 2001 |
| Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia P Ntziachristos, A Tsirigos, GG Welstead, T Trimarchi, S Bakogianni, L Xu, ... Nature 514 (7523), 513-517, 2014 | 356 | 2014 |
| Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: visualizing the therapeutic effects of metformin in tumor tissue D Whitaker-Menezes, UE Martinez-Outschoorn, N Flomenberg, R Birbe, ... Cell cycle 10 (23), 4047-4064, 2011 | 332 | 2011 |
| The autophagic tumor stroma model of cancer: Role of oxidative stress and ketone production in fueling tumor cell metabolism S Pavlides, A Tsirigos, G Migneco, D Whitaker-Menezes, B Chiavarina, ... Cell cycle 9 (17), 3485-3505, 2010 | 270 | 2010 |
| Autophagy and senescence in cancer-associated fibroblasts metabolically supports tumor growth and metastasis, via glycolysis and ketone production C Capparelli, C Guido, D Whitaker-Menezes, G Bonuccelli, R Balliet, ... Cell cycle 11 (12), 2285-2302, 2012 | 256 | 2012 |
| Analysis of multipath routing-Part I: The effect on the packet delivery ratio A Tsirigos, ZJ Haas IEEE Transactions on wireless communications 3 (1), 138-146, 2004 | 254 | 2004 |
| CXCL12-producing vascular endothelial niches control acute T cell leukemia maintenance LA Pitt, AN Tikhonova, H Hu, T Trimarchi, B King, Y Gong, ... Cancer cell 27 (6), 755-768, 2015 | 247 | 2015 |
| Loss of stromal caveolin-1 leads to oxidative stress, mimics hypoxia and drives inflammation in the tumor microenvironment, conferring the “reverse Warburg effect”: a … S Pavlides, A Tsirigos, I Vera, N Flomenberg, PG Frank, MC Casimiro, ... Cell cycle 9 (11), 2201-2219, 2010 | 246 | 2010 |
| Understanding the" lethal" drivers of tumor-stroma co-evolution: emerging role (s) for hypoxia, oxidative stress and autophagy/mitophagy in the tumor microenvironment MP Lisanti, UE Martinez-Outschoorn, B Chiavarina, S Pavlides, ... Cancer biology & therapy 10 (6), 537-542, 2010 | 225 | 2010 |
Iannis AifantisNYU Grossman School of MedicineVerified email at nyulangone.org
