| Carbonyl sulfide-mediated prebiotic formation of peptides L Leman, L Orgel, MR Ghadiri Science 306 (5694), 283-286, 2004 | 409 | 2004 |
| Prebiotic peptides: Molecular hubs in the origin of life M Frenkel-Pinter, M Samanta, G Ashkenasy, LJ Leman Chemical reviews 120 (11), 4707-4765, 2020 | 228 | 2020 |
| Self-assembling sequence-adaptive peptide nucleic acids Y Ura, JM Beierle, LJ Leman, LE Orgel, MR Ghadiri Science 325 (5936), 73-77, 2009 | 223 | 2009 |
| Selective incorporation of proteinaceous over nonproteinaceous cationic amino acids in model prebiotic oligomerization reactions M Frenkel-Pinter, JW Haynes, AS Petrov, BT Burcar, R Krishnamurthy, ... Proceedings of the National Academy of Sciences 116 (33), 16338-16346, 2019 | 97 | 2019 |
| Molecules that mimic apolipoprotein AI: potential agents for treating atherosclerosis LJ Leman, BE Maryanoff, MR Ghadiri Journal of medicinal chemistry 57 (6), 2169-2196, 2014 | 89 | 2014 |
| Amino acid dependent formation of phosphate anhydrides in water mediated by carbonyl sulfide LJ Leman, LE Orgel, MR Ghadiri Journal of the American Chemical Society 128 (1), 20-21, 2006 | 89 | 2006 |
| Coiled coils at the edge of configurational heterogeneity. Structural analyses of parallel and antiparallel homotetrameric coiled coils reveal configurational sensitivity to a … MK Yadav, LJ Leman, DJ Price, CL Brooks, CD Stout, MR Ghadiri Biochemistry 45 (14), 4463-4473, 2006 | 87 | 2006 |
| Mimicry of high-density lipoprotein: functional peptide–lipid nanoparticles based on multivalent peptide constructs Y Zhao, T Imura, LJ Leman, LK Curtiss, BE Maryanoff, MR Ghadiri Journal of the American Chemical Society 135 (36), 13414-13424, 2013 | 83 | 2013 |
| Directed remodeling of the mouse gut microbiome inhibits the development of atherosclerosis PB Chen, AS Black, AL Sobel, Y Zhao, P Mukherjee, B Molparia, ... Nature biotechnology 38 (11), 1288-1297, 2020 | 82 | 2020 |
| Mutually stabilizing interactions between proto-peptides and RNA M Frenkel-Pinter, JW Haynes, AM Mohyeldin, AB Sargon, AS Petrov, ... Nature Communications 11 (1), 3137, 2020 | 73 | 2020 |
| Discovery of HDAC Inhibitors That Lack an Active Site Zn2+-Binding Functional Group CJ Vickers, CA Olsen, LJ Leman, MR Ghadiri ACS medicinal chemistry letters 3 (6), 505-508, 2012 | 70 | 2012 |
| Macrocyclic peptoid–peptide hybrids as inhibitors of class I histone deacetylases CA Olsen, A Montero, LJ Leman, MR Ghadiri ACS Medicinal Chemistry Letters 3 (9), 749-753, 2012 | 56 | 2012 |
| Structure-Based Engineering of Internal Cavities in Coiled-Coil Peptides, MK Yadav, JE Redman, LJ Leman, JM Alvarez-Gutiérrez, Y Zhang, ... Biochemistry 44 (28), 9723-9732, 2005 | 53 | 2005 |
| In vivo efficacy of HDL-like nanolipid particles containing multivalent peptide mimetics of apolipoprotein AI [S] Y Zhao, AS Black, DJ Bonnet, BE Maryanoff, LK Curtiss, LJ Leman, ... Journal of lipid research 55 (10), 2053-2063, 2014 | 43 | 2014 |
| Dynamic polythioesters via ring-opening polymerization of 1, 4-thiazine-2, 5-diones Y Ura, M Al-Sayah, J Montenegro, JM Beierle, LJ Leman, MR Ghadiri Organic & biomolecular chemistry 7 (14), 2878-2884, 2009 | 43 | 2009 |
| Natural and synthetic macrocyclic inhibitors of the histone deacetylase enzymes AR Maolanon, HME Kristensen, LJ Leman, MR Ghadiri, CA Olsen ChemBioChem 18 (1), 5-49, 2017 | 42 | 2017 |
| Thioesters provide a plausible prebiotic path to proto-peptides M Frenkel-Pinter, M Bouza, FM Fernández, LJ Leman, LD Williams, ... Nature communications 13 (1), 2569, 2022 | 33 | 2022 |
| Cyclic tetrapeptide HDAC inhibitors as potential therapeutics for spinal muscular atrophy: Screening with iPSC-derived neuronal cells JI Lai, LJ Leman, S Ku, CJ Vickers, CA Olsen, A Montero, MR Ghadiri, ... Bioorganic & Medicinal Chemistry Letters 27 (15), 3289-3293, 2017 | 32 | 2017 |
| Potential agents for treating cystic fibrosis: cyclic tetrapeptides that restore trafficking and activity of ΔF508-CFTR DM Hutt, CA Olsen, CJ Vickers, D Herman, MA Chalfant, A Montero, ... ACS medicinal chemistry letters 2 (9), 703-707, 2011 | 31 | 2011 |
| Self-Assembling Cyclic d,l-α-Peptides as Modulators of Plasma HDL Function. A Supramolecular Approach toward Antiatherosclerotic Agents Y Zhao, LJ Leman, DJ Search, RA Garcia, DA Gordon, BE Maryanoff, ... ACS Central Science 3 (6), 639-646, 2017 | 30 | 2017 |
