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David Sexton
David Sexton
Verified email at biogen.com
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Cited by
Cited by
Year
Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis
S Sawcer, G Hellenthal, M Pirinen, CC Spencer, NA Patsopoulos, ...
Nature 476, 214-219, 2011
29562011
Genetic variation in eleven phase I drug metabolism genes in an ethnically diverse population
JF Solus, BJ Arietta, JR Harris, DP Sexton, JQ Steward, C McMunn, ...
Pharmacogenomics 5 (7), 895-931, 2004
2912004
Human mitogen-activated protein kinase kinase 4 as a candidate tumor suppressor
DHF Teng, WL Perry III, JK Hogan, M Baumgard, R Bell, S Berry, T Davis, ...
Cancer research 57 (19), 4177-4182, 1997
2461997
A major predisposition locus for severe obesity, at 4p15-p14
S Stone, V Abkevich, SC Hunt, A Gutin, DL Russell, CD Neff, R Riley, ...
The American Journal of Human Genetics 70 (6), 1459-1468, 2002
1572002
Replication analysis identifies TYK2 as a multiple sclerosis susceptibility factor
M Ban, A Goris, ÅR Lorentzen, A Baker, T Mihalova, G Ingram, DR Booth, ...
European journal of human genetics 17 (10), 1309-1313, 2009
1532009
The expanding genetic overlap between multiple sclerosis and type I diabetes
DR Booth, RN Heard, GJ Stewart, A Goris, R Dobosi, B Dubois, ...
Genes and Immunity 10 (1), 11-14, 2008
1392008
Systematic single-variant and gene-based association testing of thousands of phenotypes in 394,841 UK Biobank exomes
KJ Karczewski, M Solomonson, KR Chao, JK Goodrich, G Tiao, W Lu, ...
Cell Genomics 2 (9), 2022
1042022
Refining genetic associations in multiple sclerosis
D Booth, R Heard, G Stewart, A Goris, R Dobosi, B Dubois, A Oturai, ...
The Lancet Neurology 7 (7), 567-569, 2008
87*2008
Novel rare variants in congenital cardiac arrhythmia genes are frequent in drug-induced torsades de pointes
AH Ramirez, CM Shaffer, JT Delaney, DP Sexton, SE Levy, MJ Rieder, ...
The pharmacogenomics journal 13 (4), 325-329, 2013
842013
Managing and analyzing next-generation sequence data
BG Richter, DP Sexton
PLoS computational biology 5 (6), e1000369, 2009
752009
Finding unique filter sets in PLATO: a precursor to efficient interaction analysis in GWAS data
BJ Grady, E Torstenson, SM Dudek, J Giles, D Sexton, MD Ritchie
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 315, 2010
612010
Localization of SMAD5 and its evaluation as a candidate myeloid tumor suppressor.
DP Hejlik, LV Kottickal, H Liang, J Fairman, T Davis, T Janecki, D Sexton, ...
Cancer research 57 (17), 3779-3783, 1997
391997
A non-synonymous SNP within membrane metalloendopeptidase-like 1 (MMEL1) is associated with multiple sclerosis
M Ban, JL McCauley, R Zuvich, A Baker, L Bergamaschi, M Cox, ...
Genes & Immunity 11 (8), 660-664, 2010
372010
Lack of support for association between the KIF1B rs10492972 [C] variant and multiple sclerosis
DR Booth, RN Heard, GJ Stewart, M Cox, RJ Scott, J Lechner-Scott, ...
Nature genetics 42 (6), 469, 2010
292010
Systematic single-variant and gene-based association testing of thousands of phenotypes in 426,370 UK Biobank exomes
KJ Karczewski, M Solomonson, KR Chao, JK Goodrich, G Tiao, W Lu, ...
Medrxiv, 2021.06. 19.21259117, 2021
272021
Consanguinity mapping of congenital heart disease in a South Indian population
TL McGregor, A Misri, J Bartlett, G Orabona, RD Friedman, D Sexton, ...
PloS one 5 (4), e10286, 2010
232010
cellxgene VIP unleashes full power of interactive visualization, plotting and analysis of scRNA-seq data in the scale of millions of cells
K Li, Z Ouyang, D Lin, M Mingueneau, W Chen, D Sexton, B Zhang
BioRxiv, 2020.2008. 2028.270652, 2020
132020
The need for centralization of computational biology resources
F Lewitter, M Rebhan, B Richter, D Sexton
PLOS computational biology 5 (6), e1000372, 2009
122009
CellDepot: A unified repository for scRNA-seq data and visual exploration
D Lin, Y Chen, S Negi, D Cheng, Z Ouyang, D Sexton, K Li, B Zhang
Journal of molecular biology 434 (11), 167425, 2022
72022
The burden of rare protein-truncating genetic variants on human lifespan
JZ Liu, CY Chen, EA Tsai, CD Whelan, D Sexton, S John, H Runz
Nature Aging 2 (4), 289-294, 2022
72022
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