| Computational drug discovery S Ou-Yang, J Lu, X Kong, Z Liang, C Luo, H Jiang Acta Pharmacologica Sinica 33 (9), 1131-1140, 2012 | 381 | 2012 |
| Protein cysteine phosphorylation of SarA/MgrA family transcriptional regulators mediates bacterial virulence and antibiotic resistance F Sun, Y Ding, Q Ji, Z Liang, X Deng, CCL Wong, C Yi, L Zhang, S Xie, ... Proceedings of the National Academy of Sciences 109 (38), 15461-15466, 2012 | 187 | 2012 |
| Extensive crosstalk between O-GlcNAcylation and phosphorylation regulates Akt signaling S Wang, X Huang, D Sun, X Xin, Q Pan, S Peng, Z Liang, C Luo, Y Yang, ... PloS one 7 (5), e37427, 2012 | 146 | 2012 |
| Molecular basis of NDM-1, a new antibiotic resistance determinant Z Liang, L Li, Y Wang, L Chen, X Kong, Y Hong, L Lan, M Zheng, ... PLoS One 6 (8), e23606, 2011 | 81 | 2011 |
| Pharmacophore-based virtual screening and biological evaluation of small molecule inhibitors for protein arginine methylation J Wang, L Chen, SH Sinha, Z Liang, H Chai, S Muniyan, YW Chou, ... Journal of medicinal chemistry 55 (18), 7978-7987, 2012 | 79 | 2012 |
| DNA methyltransferase inhibitors: an updated patent review (2012-2015) P Xu, G Hu, C Luo, Z Liang Expert opinion on therapeutic patents 26 (9), 1017-1030, 2016 | 65 | 2016 |
| Network modelling reveals the mechanism underlying colitis-associated colon cancer and identifies novel combinatorial anti-cancer targets J Lu, H Zeng, Z Liang, L Chen, L Zhang, H Zhang, H Liu, H Jiang, B Shen, ... Scientific reports 5 (1), 14739, 2015 | 58 | 2015 |
| Catalytic mechanism investigation of lysine-specific demethylase 1 (LSD1): a computational study X Kong, S Ouyang, Z Liang, J Lu, L Chen, B Shen, D Li, M Zheng, KK Li, ... PLoS One 6 (9), e25444, 2011 | 58 | 2011 |
| Integration of network models and evolutionary analysis into high-throughput modeling of protein dynamics and allosteric regulation: theory, tools and applications Z Liang, GM Verkhivker, G Hu Briefings in bioinformatics 21 (3), 815-835, 2020 | 56 | 2020 |
| Structural optimization and biological evaluation of substituted bisphenol a derivatives as β-amyloid peptide aggregation inhibitors Y Zhou, C Jiang, Y Zhang, Z Liang, W Liu, L Wang, C Luo, T Zhong, Y Sun, ... Journal of medicinal chemistry 53 (15), 5449-5466, 2010 | 49 | 2010 |
| Identification of pentacyclic triterpenes derivatives as potent inhibitors against glycogen phosphorylase based on 3D-QSAR studies Z Liang, L Zhang, L Li, J Liu, H Li, L Zhang, L Chen, K Cheng, M Zheng, ... European journal of medicinal chemistry 46 (6), 2011 | 46 | 2011 |
| Identification and synthesis of N′-(2-oxoindolin-3-ylidene) hydrazide derivatives against c-Met kinase Z Liang, D Zhang, J Ai, L Chen, H Wang, X Kong, M Zheng, H Liu, C Luo, ... Bioorganic & medicinal chemistry letters 21 (12), 3749-3754, 2011 | 44 | 2011 |
| Catalytic mechanism of histone acetyltransferase p300: from the proton transfer to acetylation reaction X Zhang, S Ouyang, X Kong, Z Liang, J Lu, K Zhu, D Zhao, M Zheng, ... The Journal of Physical Chemistry B 118 (8), 2009-2019, 2014 | 43 | 2014 |
| Investigation of the acetylation mechanism by GCN5 histone acetyltransferase J Jiang, J Lu, D Lu, Z Liang, L Li, S Ouyang, X Kong, H Jiang, B Shen, ... PLoS One 7 (5), e36660, 2012 | 43 | 2012 |
| A quantum mechanics/molecular mechanics study on the hydrolysis mechanism of New Delhi metallo-β-lactamase-1 K Zhu, J Lu, Z Liang, X Kong, F Ye, L Jin, H Geng, Y Chen, M Zheng, ... Journal of computer-aided molecular design 27, 247-256, 2013 | 42 | 2013 |
| Drug design targeting active posttranslational modification protein isoforms F Meng, Z Liang, K Zhao, C Luo Medicinal research reviews 41 (3), 1701-1750, 2021 | 36 | 2021 |
| c-MET kinase inhibitors: a patent review (2011–2013) K Zhu, X Kong, D Zhao, Z Liang, C Luo Expert opinion on therapeutic patents 24 (2), 217-230, 2014 | 33 | 2014 |
| Discovery of novel 2-aminopyridine-3-carboxamides as c-Met kinase inhibitors D Zhang, J Ai, Z Liang, C Li, X Peng, YC Ji, H Jiang, M Geng, C Luo, H Liu Bioorganic & medicinal chemistry 20 (17), 5169-5180, 2012 | 33 | 2012 |
| Molecular mechanism underlying PRMT1 dimerization for SAM binding and methylase activity R Zhou, Y Xie, H Hu, G Hu, VS Patel, J Zhang, K Yu, Y Huang, H Jiang, ... Journal of chemical information and modeling 55 (12), 2623-2632, 2015 | 31 | 2015 |
| Virtual screening and biological evaluation of novel small molecular inhibitors against protein arginine methyltransferase 1 (PRMT1) Y Xie, R Zhou, F Lian, Y Liu, L Chen, Z Shi, N Zhang, M Zheng, B Shen, ... Organic & biomolecular chemistry 12 (47), 9665-9673, 2014 | 31 | 2014 |
Xiangqian KongCenter for Chemical Biology and Drug Discovery, GIBHVerified email at gibh.ac.cn
