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Muharrem Akcan, PhD
Muharrem Akcan, PhD
Kütahya Dumlupınar University, Department of Biochemistry
Verified email at dpu.edu.tr
Title
Cited by
Cited by
Year
Oxytocic plant cyclotides as templates for peptide G protein-coupled receptor ligand design
J Koehbach, M O’Brien, M Muttenthaler, M Miazzo, M Akcan, AG Elliott, ...
Proceedings of the National Academy of Sciences 110 (52), 21183-21188, 2013
1582013
Chemical re-engineering of chlorotoxin improves bioconjugation properties for tumor imaging and targeted therapy
M Akcan, MR Stroud, SJ Hansen, RJ Clark, NL Daly, DJ Craik, JM Olson
Journal of Medicinal chemistry 54 (3), 782-787, 2011
1182011
Cyclization of conotoxins to improve their biopharmaceutical properties
RJ Clark, M Akcan, Q Kaas, NL Daly, DJ Craik
Toxicon 59 (4), 446-455, 2012
952012
Design and synthesis of truncated EGF-A peptides that restore LDL-R recycling in the presence of PCSK9 in vitro
CI Schroeder, JE Swedberg, JM Withka, KJ Rosengren, M Akcan, ...
Chemistry & biology 21 (2), 284-294, 2014
792014
Characterization of a Novel Alpha-Conotoxin TxID from Conus textile that Potently Blocks rat Alpha3beta4 Nicotinic Acetylcholine Receptors
S Luo, D Zhangsun, X Zhu, Y Wu, Y Hu, S Christensen, PJ Harvey, ...
Journal of Medicinal Chemistry, 2013
792013
Engineered protease inhibitors based on sunflower trypsin inhibitor-1 (SFTI-1) provide insights into the role of sequence and conformation in Laskowski mechanism inhibition
SJ de Veer, JE Swedberg, M Akcan, KJ Rosengren, M Brattsand, DJ Craik, ...
Biochemical Journal 469 (2), 243-253, 2015
672015
Characterization of a novel α-conotoxin from conus textile that selectively targets α6/α3β2β3 nicotinic acetylcholine receptors
S Luo, D Zhangsun, Y Wu, X Zhu, Y Hu, M McIntyre, S Christensen, ...
Journal of Biological Chemistry 288 (2), 894-902, 2013
612013
Less is more: design of a highly stable disulfide-deleted mutant of analgesic cyclic α-conotoxin Vc1. 1
R Yu, VAL Seymour, G Berecki, X Jia, M Akcan, DJ Adams, Q Kaas, ...
Scientific reports 5 (13264), 2015
542015
Synthesis of new thiophene, furan and pyridine substituted 1, 2, 4, 5-oxadiazaboroles
Y Dürüst, M Akcan, O Martiskainen, E Siirola, K Pihlaja
Polyhedron 27 (3), 999-1007, 2008
232008
Transforming conotoxins into cyclotides: backbone cyclization of P‐superfamily conotoxins
M Akcan, RJ Clark, NL Daly, AC Conibear, A de Faoite, MD Heghinian, ...
Peptide Science 104 (6), 682-692, 2015
172015
Synthesis of cyclic disulfide-rich peptides
M Akcan, DJ Craik
Peptide Synthesis and Applications, 89-101, 2013
132013
Potentiometric Study of Acid− Base Equilibria of 3, 5-Disubstituted 1, 2, 4, 5-Oxadiazaboroles in Nonaqueous Media
Y Dürüst, N Dürüst, M Akcan
Journal of Chemical & Engineering Data 52 (3), 718-720, 2007
132007
Characterization of a novel a-conotoxin from conus textile that selectively targets a6/a3b2b3 nicotinic acetylcholine receptors
S Luo, D Zhangsun, Y Wu, X Zhu, Y Hu, M McIntyre, S Christensen, ...
J. Biol. Chem 288, 894-902, 2013
112013
The three-dimensional solution structure of mini-M conotoxin BtIIIA reveals a disconnection between disulfide connectivity and peptide fold
M Akcan, Y Cao, F Chongxu, DJ Craik
Bioorganic & Medicinal Chemistry, 2013
82013
Preparation, Characterization and Antibacterial Activity of Malva Sylvestris L. Seed Extract Containing Novel Electrospun PVA Nanofibers
K Turan, M Akcan, OM Kalfa
Gazi University Journal of Science 34 (4), 987-998, 2021
52021
Engineering venom peptides to improve their stability and bioavailability
M Akcan, DJ Craik
Venoms to Drugs: Venom as a Source for the Development of Human Therapeutics …, 2015
52015
Discovery and applications of naturally occurring cyclic peptides
D Craik, A Poth, M Colgrave, M Akcan, B Oku, A Chan, N Daly
Planta Medica 77 (12), L8, 2011
32011
The ring closure reactions of amidoximes with phenylboronic acid
M Akcan
Fen Bilimleri Enstitüsü, 2007
32007
Enhancing the Stability of Tumor Homing LyP-1 Peptide Using Cyclization and Retro Grafting Strategies
Ş Kara, E Ayazoglu Demir, S Celik Uzuner, M Akcan
International Journal of Peptide Research and Therapeutics 29 (2), 30, 2023
12023
Cyclotide-rich fractions containing nanofibers by electrospinning: preparation, characterization and examination of antimicrobial activity
EB BAŞ, C KÜREKCİ, OM Kalfa, M Akcan
Turkish Journal of Chemistry 46 (5), 1651-1660, 2022
12022
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Articles 1–20