| Properties and applications of starch-converting enzymes of the α-amylase family MJEC Van Der Maarel, B Van der Veen, JCM Uitdehaag, H Leemhuis, ... Journal of biotechnology 94 (2), 137-155, 2002 | 1918 | 2002 |
| Glucansucrases: three-dimensional structures, reactions, mechanism, α-glucan analysis and their implications in biotechnology and food applications H Leemhuis, T Pijning, JM Dobruchowska, SS van Leeuwen, S Kralj, ... Journal of biotechnology 163 (2), 250-272, 2013 | 337 | 2013 |
| Engineering of cyclodextrin glucanotransferases and the impact for biotechnological applications H Leemhuis, RM Kelly, L Dijkhuizen Applied microbiology and biotechnology 85, 823-835, 2010 | 224 | 2010 |
| Directed evolution of enzymes: Library screening strategies H Leemhuis, RM Kelly, L Dijkhuizen IUBMB life 61 (3), 222-228, 2009 | 178 | 2009 |
| Starch modification with microbial alpha-glucanotransferase enzymes MJEC van der Maarel, H Leemhuis Carbohydrate polymers 93 (1), 116-121, 2013 | 166 | 2013 |
| New genotype–phenotype linkages for directed evolution of functional proteins H Leemhuis, V Stein, AD Griffiths, F Hollfelder Current Opinion in Structural Biology 15 (4), 472-478, 2005 | 165 | 2005 |
| Hydrophobic amino acid residues in the acceptor binding site are main determinants for reaction mechanism and specificity of cyclodextrin-glycosyltransferase BA van der Veen, H Leemhuis, S Kralj, JCM Uitdehaag, BW Dijkstra, ... Journal of Biological Chemistry 276 (48), 44557-44562, 2001 | 131 | 2001 |
| Inulin and levan synthesis by probiotic Lactobacillus gasseri strains: characterization of three novel fructansucrase enzymes and their fructan products MA Anwar, S Kralj, AV Pique, H Leemhuis, MJEC van der Maarel, ... Microbiology 156 (4), 1264-1274, 2010 | 129 | 2010 |
| Thermus thermophilus glycoside hydrolase family 57 branching enzyme: crystal structure, mechanism of action, and products formed M Palomo, T Pijning, T Booiman, JM Dobruchowska, J Van Der Vlist, ... Journal of biological chemistry 286 (5), 3520-3530, 2011 | 114 | 2011 |
| Characterization of the Gene Cluster Involved in Isoprene Metabolism in Rhodococcus sp. Strain AD45 JET van Hylckama Vlieg, H Leemhuis, JHL Spelberg, DB Janssen Journal of Bacteriology 182 (7), 1956-1963, 2000 | 111 | 2000 |
| Isomalto/malto-polysaccharide, a novel soluble dietary fiber made via enzymatic conversion of starch H Leemhuis, JM Dobruchowska, M Ebbelaar, F Faber, PL Buwalda, ... Journal of agricultural and food chemistry 62 (49), 12034-12044, 2014 | 106 | 2014 |
| 4, 6-α-Glucanotransferase, a novel enzyme that structurally and functionally provides an evolutionary link between glycoside hydrolase enzyme families 13 and 70 S Kralj, P Grijpstra, SS van Leeuwen, H Leemhuis, JM Dobruchowska, ... Applied and environmental microbiology 77 (22), 8154-8163, 2011 | 104 | 2011 |
| The evolution of cyclodextrin glucanotransferase product specificity RM Kelly, L Dijkhuizen, H Leemhuis Applied microbiology and biotechnology 84 (1), 119-133, 2009 | 97 | 2009 |
| Starch and α-glucan acting enzymes, modulating their properties by directed evolution RM Kelly, L Dijkhuizen, H Leemhuis Journal of Biotechnology 140 (3-4), 184-193, 2009 | 80 | 2009 |
| Structural characterization of linear isomalto-/malto-oligomer products synthesized by the novel GTFB 4, 6-α-glucanotransferase enzyme from Lactobacillus reuteri 121 JM Dobruchowska, GJ Gerwig, S Kralj, P Grijpstra, H Leemhuis, ... Glycobiology 22 (4), 517-528, 2012 | 77 | 2012 |
| Conversion of Cyclodextrin Glycosyltransferase into a Starch Hydrolase by Directed Evolution: The Role of Alanine 230 in Acceptor Subsite +1, H Leemhuis, HJ Rozeboom, M Wilbrink, GJW Euverink, BW Dijkstra, ... Biochemistry 42 (24), 7518-7526, 2003 | 77 | 2003 |
| 4,6-α-Glucanotransferase activity occurs more widespread in Lactobacillus strains and constitutes a separate GH70 subfamily H Leemhuis, WP Dijkman, JM Dobruchowska, T Pijning, P Grijpstra, ... Applied microbiology and biotechnology 97 (1), 181-193, 2013 | 76 | 2013 |
| The human histone acetyltransferase P/CAF is a promiscuous histone propionyltransferase H Leemhuis, LC Packman, KP Nightingale, F Hollfelder ChemBioChem 9 (4), 499-503, 2008 | 76 | 2008 |
| Biochemical characterization of the Lactobacillus reuteri glycoside hydrolase family 70 GTFB type of 4, 6-α-glucanotransferase enzymes that synthesize soluble dietary starch fibers Y Bai, RM van der Kaaij, H Leemhuis, T Pijning, SS van Leeuwen, Z Jin, ... Applied and Environmental Microbiology 81 (20), 7223-7232, 2015 | 74 | 2015 |
| Crystal structure of inulosucrase from Lactobacillus: insights into the substrate specificity and product specificity of GH68 fructansucrases T Pijning, MA Anwar, M Böger, JM Dobruchowska, H Leemhuis, S Kralj, ... Journal of molecular biology 412 (1), 80-93, 2011 | 74 | 2011 |
L. DijkhuizenCSO CarbExplore Research BV, em. Professor of Microbiology, University of GroningenVerified email at rug.nl
