| Mutations in the homeobox gene HESX1/Hesx1 associated with septo-optic dysplasia in human and mouse MT Dattani, JP Martinez-Barbera, PQ Thomas, JM Brickman, R Gupta, ... Nature genetics 19 (2), 125-133, 1998 | 899 | 1998 |
| Time-resolved analysis reveals rapid dynamics and broad scope of the CBP/p300 acetylome BT Weinert, T Narita, S Satpathy, B Srinivasan, BK Hansen, C Schölz, ... Cell 174 (1), 231-244. e12, 2018 | 351 | 2018 |
| Heterozygous HESX1 mutations associated with isolated congenital pituitary hypoplasia and septo-optic dysplasia PQ Thomas, MT Dattani, JM Brickman, D McNay, G Warne, M Zacharin, ... Human molecular genetics 10 (1), 39-45, 2001 | 348 | 2001 |
| Functional heterogeneity of embryonic stem cells revealed through translational amplification of an early endodermal transcript MA Canham, AA Sharov, MSH Ko, JM Brickman PLoS biology 8 (5), e1000379, 2010 | 278 | 2010 |
| An HMG-like protein that can switch a transcriptional activator to a repressor N Lehming, D Thanos, JM Brickman, J Ma, T Maniatis, M Ptashne Nature 371 (6493), 175-179, 1994 | 276 | 1994 |
| Totipotent embryonic stem cells arise in ground-state culture conditions SM Morgani, MA Canham, J Nichols, AA Sharov, RP Migueles, MSH Ko, ... Cell reports 3 (6), 1945-1957, 2013 | 257 | 2013 |
| Conserved roles for Oct4 homologues in maintaining multipotency during early vertebrate development GM Morrison, JM Brickman Oxford University Press for The Company of Biologists Limited 133 (10), 2011 …, 2006 | 201 | 2006 |
| Targeted Mutagenesis of the Hira Gene Results in Gastrulation Defects and Patterning Abnormalities of Mesoendodermal Derivatives Prior to Early Embryonic … C Roberts, HF Sutherland, H Farmer, W Kimber, S Halford, A Carey, ... Molecular and cellular biology 22 (7), 2318-2328, 2002 | 166 | 2002 |
| A homozygous mutation in HESX1 is associated with evolving hypopituitarism due to impaired repressor-corepressor interaction LR Carvalho, KS Woods, BB Mendonca, N Marcal, AL Zamparini, S Stifani, ... The Journal of clinical investigation 112 (8), 1192-1201, 2003 | 158 | 2003 |
| Molecular effects of novel mutations in Hesx1/HESX1 associated with human pituitary disorders JM Brickman, M Clements, R Tyrell, D McNay, K Woods, J Warner, ... Oxford University Press for The Company of Biologists Limited 128 (24), 5189 …, 2001 | 156 | 2001 |
| Anterior definitive endoderm from ESCs reveals a role for FGF signaling GM Morrison, I Oikonomopoulou, RP Migueles, S Soneji, A Livigni, ... Cell Stem Cell 3 (4), 402-415, 2008 | 147 | 2008 |
| Naïve human pluripotent stem cells respond to Wnt, Nodal and LIF signalling to produce expandable naïve extra-embryonic endoderm M Linneberg-Agerholm, YF Wong, JA Romero Herrera, RS Monteiro, ... Development 146 (24), dev180620, 2019 | 136 | 2019 |
| Properties of embryoid bodies JM Brickman, P Serup Wiley Interdisciplinary Reviews: Developmental Biology 6 (2), e259, 2017 | 127 | 2017 |
| Hex is a transcriptional repressor that contributes to anterior identity and suppresses Spemann organiser function JM Brickman, CM Jones, M Clements, JC Smith, RSP Beddington Development 127 (11), 2303-2315, 2000 | 123 | 2000 |
| Gene expression heterogeneities in embryonic stem cell populations: origin and function AM Arias, JM Brickman Current opinion in cell biology 23 (6), 650-656, 2011 | 117 | 2011 |
| Erk signaling suppresses embryonic stem cell self-renewal to specify endoderm WB Hamilton, JM Brickman Cell reports 9 (6), 2056-2070, 2014 | 111 | 2014 |
| New eukaryotic transcriptional repressers S Saha, JM Brickman, N Lehming, M Ptashne Nature 363 (6430), 648-652, 1993 | 103 | 1993 |
| Enhancers are activated by p300/CBP activity-dependent PIC assembly, RNAPII recruitment, and pause release T Narita, S Ito, Y Higashijima, WK Chu, K Neumann, J Walter, S Satpathy, ... Molecular cell 81 (10), 2166-2182. e6, 2021 | 101 | 2021 |
| Interactions between an HMG-1 protein and members of the Rel family JM Brickman, M Adam, M Ptashne Proceedings of the National Academy of Sciences 96 (19), 10679-10683, 1999 | 92 | 1999 |
| Transcriptional activation by Oct4 is sufficient for the maintenance and induction of pluripotency F Hammachi, GM Morrison, AA Sharov, A Livigni, S Narayan, ... Cell reports 1 (2), 99-109, 2012 | 87 | 2012 |
