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Prakasha Kempaiah, PhD
Prakasha Kempaiah, PhD
Associate Consultant, Mayo Clinic, Jacksonville, Florida
Email verificata su mayo.edu - Home page
Titolo
Citata da
Citata da
Anno
Severe malarial anemia: innate immunity and pathogenesis
DJ Perkins, T Were, GC Davenport, P Kempaiah, JB Hittner, JM Ong'echa
International journal of biological sciences 7 (9), 1427, 2011
4082011
Natural infection of Plasmodium brasilianum in humans: man and monkey share quartan malaria parasites in the Venezuelan Amazon
A Lalremruata, M Magris, S Vivas-Martínez, M Koehler, M Esen, ...
EBioMedicine 2 (9), 1186-1192, 2015
1642015
Discovery of New Hydroxyethylamine Analogs against 3CLpro Protein Target of SARS-CoV-2: Molecular Docking, Molecular Dynamics Simulation, and Structure–Activity Relationship …
S Kumar, PP Sharma, U Shankar, D Kumar, SK Joshi, L Pena, ...
J. Chem. Inf. Model, 2020
1172020
Mycobacterium abscessus glycopeptidolipid prevents respiratory epithelial TLR2 signaling as measured by HβD2 gene expression and IL-8 release
LB Davidson, R Nessar, P Kempaiah, DJ Perkins, TF Byrd
PloS one 6 (12), e29148, 2011
702011
Mechanisms of erythropoiesis inhibition by malarial pigment and malaria‐induced proinflammatory mediators in an in vitro model
GA Awandare, P Kempaiah, DO Ochiel, P Piazza, CC Keller, DJ Perkins
American journal of hematology 86 (2), 155-162, 2011
662011
A review of the preclinical and clinical efficacy of remdesivir, hydroxychloroquine, and lopinavir-ritonavir treatments against COVID-19
D Maciorowski, SZE Idrissi, Y Gupta, BJ Medernach, MB Burns, ...
SLAS DISCOVERY: Advancing the Science of Drug Discovery 25 (10), 1108-1122, 2020
402020
Human tissue factor pathway inhibitor-2 induces caspase-mediated apoptosis in a human fibrosarcoma cell line
P Kempaiah, W Kisiel
Apoptosis 13, 702-715, 2008
382008
Identification of a human TFPI-2 splice variant that is upregulated in human tumor tissues
P Kempaiah, HS Chand, W Kisiel
Molecular cancer 6, 1-11, 2007
362007
Functional haplotypes of Fc gamma (Fcγ) receptor (FcγRIIA and FcγRIIIB) predict risk to repeated episodes of severe malarial anemia and mortality in Kenyan children
C Ouma, GC Davenport, S Garcia, P Kempaiah, A Chaudhary, T Were, ...
Human genetics 131, 289-299, 2012
352012
Bisindolylmaleimide IX: A novel anti-SARS-CoV2 agent targeting viral main protease 3CLpro demonstrated by virtual screening pipeline and in-vitro validation assays
Y Gupta, D Maciorowski, SE Zak, KA Jones, RS Kathayat, SA Azizi, ...
Methods 195, 57-71, 2021
332021
Fluorinated scaffolds for antimalarial drug discovery
C Upadhyay, M Chaudhary, RN De Oliveira, A Borbas, P Kempaiah, P S, ...
Expert Opinion on Drug Discovery 15 (6), 705-718, 2020
322020
Heparin: A simplistic repurposing to prevent SARS-CoV-2 transmission in light of its in-vitro nanomolar efficacy
Y Gupta, D Maciorowski, SE Zak, CV Kulkarni, AS Herbert, R Durvasula, ...
International Journal of Biological Macromolecules 183, 203-212, 2021
292021
Antiplasmodial activity of hydroxyethylamine analogs: synthesis, biological activity and structure activity relationship of plasmepsin inhibitors
AK Singh, V Rajendran, S Singh, P Kumar, Y Kumar, A Singh, W Miller, ...
Bioorganic & medicinal chemistry 26 (13), 3837-3844, 2018
272018
Iron dysregulation in COVID‐19 and reciprocal evolution of SARS‐CoV‐2: Natura nihil frustra facit
Y Gupta, D Maciorowski, B Medernach, DP Becker, R Durvasula, ...
Journal of Cellular Biochemistry, 2022
242022
A novel compound active against SARS-CoV-2 targeting uridylate-specific endoribonuclease (NendoU/NSP15): in silico and in vitro investigations
S Kumar, Y Gupta, SE Zak, C Upadhyay, N Sharma, AS Herbert, ...
RSC Medicinal Chemistry 12 (10), 1757-1764, 2021
242021
Protein structure-based in-silico approaches to drug discovery: Guide to COVID-19 therapeutics
Y Gupta, OV Savytskyi, M Coban, A Venugopal, V Pleqi, CA Weber, ...
Molecular Aspects of Medicine 91, 101151, 2023
232023
Reduced parasite burden in children with falciparum malaria and bacteremia coinfections: role of mediators of inflammation
GC Davenport, JB Hittner, V Otieno, Z Karim, H Mukundan, PW Fenimore, ...
Mediators of inflammation 2016, 2016
222016
Functional promoter haplotypes of interleukin-18 condition susceptibility to severe malarial anemia and childhood mortality
SB Anyona, P Kempaiah, E Raballah, C Ouma, T Were, GC Davenport, ...
Infection and immunity 79 (12), 4923-4932, 2011
222011
Polymorphic variability in the 3'untranslated region (UTR) of IL12B is associated with susceptibility to severe anaemia in Kenyan children with acute Plasmodium falciparum malaria
JM Ong'echa, EO Raballah, PM Kempaiah, SB Anyona, T Were, ...
BMC genetics 12, 1-9, 2011
212011
Fast-acting small molecules targeting malarial aspartyl proteases, plasmepsins, inhibit malaria infection at multiple life stages
S Singh, V Rajendran, J He, AK Singh, AO Achieng, Vandana, A Pant, ...
ACS Infectious Diseases 5 (2), 184-198, 2018
202018
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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