Tyler S. Harmon
Tyler S. Harmon
Junior Group Leader, Leibniz Institute for Polymer Research
Verified email at
Cited by
Cited by
Coexisting liquid phases underlie nucleolar subcompartments
M Feric, N Vaidya, TS Harmon, DM Mitrea, L Zhu, TM Richardson, ...
Cell 165 (7), 1686-1697, 2016
Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins
TS Harmon, AS Holehouse, MK Rosen, RV Pappu
elife 6, e30294, 2017
Quantitative analysis of multilayer organization of proteins and RNA in nuclear speckles at super resolution
J Fei, M Jadaliha, TS Harmon, ITS Li, B Hua, Q Hao, AS Holehouse, ...
Journal of cell science 130 (24), 4180-4192, 2017
Phase separation provides a mechanism to reduce noise in cells
A Klosin, F Oltsch, T Harmon, A Honigmann, F Jülicher, AA Hyman, ...
Science 367 (6476), 464-468, 2020
Injectable tissue integrating networks from recombinant polypeptides with tunable order
S Roberts, TS Harmon, JL Schaal, V Miao, K Li, A Hunt, Y Wen, TG Oas, ...
Nature Materials 17 (12), 1154-1163, 2018
Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers
AE Posey, KM Ruff, TS Harmon, SL Crick, A Li, MI Diamond, RV Pappu
Journal of Biological Chemistry 293 (10), 3734-3746, 2018
Differential solvation of intrinsically disordered linkers drives the formation of spatially organized droplets in ternary systems of linear multivalent proteins
TS Harmon, AS Holehouse, RV Pappu
New Journal of Physics 20 (4), 045002, 2018
CAMELOT: A machine learning approach for coarse-grained simulations of aggregation of block-copolymeric protein sequences
KM Ruff, TS Harmon, RV Pappu
The Journal of chemical physics 143 (24), 12B607_1, 2015
A multi-step nucleation process determines the kinetics of prion-like domain phase separation
EW Martin, TS Harmon, JB Hopkins, S Chakravarthy, JJ Incicco, P Schuck, ...
Nature communications 12 (1), 4513, 2021
Hamiltonian switch metropolis Monte Carlo simulations for improved conformational sampling of intrinsically disordered regions tethered to ordered domains of proteins
A Mittal, N Lyle, TS Harmon, RV Pappu
Journal of chemical theory and computation 10 (8), 3550-3562, 2014
Power-law population heterogeneity governs epidemic waves
J Neipel, J Bauermann, S Bo, T Harmon, F Jülicher
PloS one 15 (10), e0239678, 2020
GADIS: Algorithm for designing sequences to achieve target secondary structure profiles of intrinsically disordered proteins
TS Harmon, MD Crabtree, SL Shammas, AE Posey, J Clarke, RV Pappu
Protein Engineering, Design and Selection 29 (9), 339-346, 2016
To mix, or to demix, that is the question
TS Harmon, AS Holehouse, RV Pappu
Biophysical Journal 112 (4), 565, 2017
Molecular assembly lines in active droplets
TS Harmon, F Jülicher
Physical review letters 128 (10), 108102, 2022
A model for hysteresis observed in phase transitions of thermally responsive intrinsically disordered protein polymers
TS Harmon, S Roberts, A Chilkoti, RV Pappu
Biophysical Journal 112 (3), 207a, 2017
Charge Patterned Sequences form Helical Structures through Charge Neutralization
TS Harmon, RV Pappu
Biophysical Journal 110 (3), 358a, 2016
An evolutionary algorithm for the design of different degrees of secondary structure in intrinsically disordered proteins (IDPs)
TS Harmon, RV Pappu
Biophysical Journal 108 (2), 228a, 2015
Increasing the Accuracy in All-Atom Simulations of Intrinsically Disordered Proteins based on the Absinth Model
MJ Fossat, TS Harmon, AE Posey, JM Choi, RV Pappu
Biophysical Journal 114 (3), 432a, 2018
Molecular assembly lines regulate the size of active droplets
T Harmon
Bulletin of the American Physical Society, 2023
Kinetic and Equilibrium Measurement of Nucleation of Prion-Like Domain Phase Separation
EW Martin, TS Harmon, JB Hopkins, S Chakravarthy, J Incicco, P Schuck, ...
Biophysical Journal 120 (3), 108a, 2021
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