Coexisting liquid phases underlie nucleolar subcompartments M Feric, N Vaidya, TS Harmon, DM Mitrea, L Zhu, TM Richardson, ... Cell 165 (7), 1686-1697, 2016 | 1319 | 2016 |
Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins TS Harmon, AS Holehouse, MK Rosen, RV Pappu elife 6, e30294, 2017 | 421 | 2017 |
Quantitative analysis of multilayer organization of proteins and RNA in nuclear speckles at super resolution J Fei, M Jadaliha, TS Harmon, ITS Li, B Hua, Q Hao, AS Holehouse, ... Journal of cell science 130 (24), 4180-4192, 2017 | 187 | 2017 |
Phase separation provides a mechanism to reduce noise in cells A Klosin, F Oltsch, T Harmon, A Honigmann, F Jülicher, AA Hyman, ... Science 367 (6476), 464-468, 2020 | 182 | 2020 |
Injectable tissue integrating networks from recombinant polypeptides with tunable order S Roberts, TS Harmon, JL Schaal, V Miao, K Li, A Hunt, Y Wen, TG Oas, ... Nature Materials 17 (12), 1154-1163, 2018 | 112 | 2018 |
Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers AE Posey, KM Ruff, TS Harmon, SL Crick, A Li, MI Diamond, RV Pappu Journal of Biological Chemistry 293 (10), 3734-3746, 2018 | 91 | 2018 |
Differential solvation of intrinsically disordered linkers drives the formation of spatially organized droplets in ternary systems of linear multivalent proteins TS Harmon, AS Holehouse, RV Pappu New Journal of Physics 20 (4), 045002, 2018 | 86 | 2018 |
CAMELOT: A machine learning approach for coarse-grained simulations of aggregation of block-copolymeric protein sequences KM Ruff, TS Harmon, RV Pappu The Journal of chemical physics 143 (24), 12B607_1, 2015 | 67 | 2015 |
A multi-step nucleation process determines the kinetics of prion-like domain phase separation EW Martin, TS Harmon, JB Hopkins, S Chakravarthy, JJ Incicco, P Schuck, ... Nature communications 12 (1), 4513, 2021 | 39 | 2021 |
Hamiltonian switch metropolis Monte Carlo simulations for improved conformational sampling of intrinsically disordered regions tethered to ordered domains of proteins A Mittal, N Lyle, TS Harmon, RV Pappu Journal of chemical theory and computation 10 (8), 3550-3562, 2014 | 33 | 2014 |
Power-law population heterogeneity governs epidemic waves J Neipel, J Bauermann, S Bo, T Harmon, F Jülicher PloS one 15 (10), e0239678, 2020 | 32 | 2020 |
GADIS: Algorithm for designing sequences to achieve target secondary structure profiles of intrinsically disordered proteins TS Harmon, MD Crabtree, SL Shammas, AE Posey, J Clarke, RV Pappu Protein Engineering, Design and Selection 29 (9), 339-346, 2016 | 19 | 2016 |
To mix, or to demix, that is the question TS Harmon, AS Holehouse, RV Pappu Biophysical Journal 112 (4), 565, 2017 | 14 | 2017 |
Molecular assembly lines in active droplets TS Harmon, F Jülicher Physical review letters 128 (10), 108102, 2022 | 3 | 2022 |
A model for hysteresis observed in phase transitions of thermally responsive intrinsically disordered protein polymers TS Harmon, S Roberts, A Chilkoti, RV Pappu Biophysical Journal 112 (3), 207a, 2017 | 2 | 2017 |
Charge Patterned Sequences form Helical Structures through Charge Neutralization TS Harmon, RV Pappu Biophysical Journal 110 (3), 358a, 2016 | 2 | 2016 |
An evolutionary algorithm for the design of different degrees of secondary structure in intrinsically disordered proteins (IDPs) TS Harmon, RV Pappu Biophysical Journal 108 (2), 228a, 2015 | 2 | 2015 |
Increasing the Accuracy in All-Atom Simulations of Intrinsically Disordered Proteins based on the Absinth Model MJ Fossat, TS Harmon, AE Posey, JM Choi, RV Pappu Biophysical Journal 114 (3), 432a, 2018 | 1 | 2018 |
Molecular assembly lines regulate the size of active droplets T Harmon Bulletin of the American Physical Society, 2023 | | 2023 |
Kinetic and Equilibrium Measurement of Nucleation of Prion-Like Domain Phase Separation EW Martin, TS Harmon, JB Hopkins, S Chakravarthy, J Incicco, P Schuck, ... Biophysical Journal 120 (3), 108a, 2021 | | 2021 |