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Loka Raghu Kumar Penke
Loka Raghu Kumar Penke
Assistant Research Scientist
Verified email at umich.edu - Homepage
Title
Cited by
Cited by
Year
Transcellular delivery of vesicular SOCS proteins from macrophages to epithelial cells blunts inflammatory signaling
E Bourdonnay, Z Zasłona, LRK Penke, JM Speth, DJ Schneider, ...
Journal of Experimental Medicine 212 (5), 729-742, 2015
2202015
Reversal of Myofibroblast Differentiation by Prostaglandin E2
G Garrison, SK Huang, K Okunishi, JP Scott, LR Kumar Penke, ...
American journal of respiratory cell and molecular biology 48 (5), 550-558, 2013
1442013
FOXM1 is a critical driver of lung fibroblast activation and fibrogenesis
LR Penke, JM Speth, VL Dommeti, ES White, IL Bergin, M Peters-Golden
The Journal of Clinical Investigation 128 (6), 2389-2405, 2018
992018
Prostaglandin E2 inhibits α-smooth muscle actin transcription during myofibroblast differentiation via distinct mechanisms of modulation of serum response factor and myocardin …
LRK Penke, SK Huang, ES White, M Peters-Golden
Journal of Biological Chemistry 289 (24), 17151-17162, 2014
892014
Mechanisms and modulation of microvesicle uptake in a model of alveolar cell communication
DJ Schneider, JM Speth, LR Penke, SH Wettlaufer, JA Swanson, ...
Journal of Biological Chemistry 292 (51), 20897-20910, 2017
762017
Distinctive Effects of GM-CSF and M-CSF on Proliferation and Polarization of Two Major Pulmonary Macrophage Populations
C Draijer, LRK Penke, M Peters-Golden
Journal of Immunology 202 (9), 2700-2709, 2019
552019
Myofibroblast de-differentiation proceeds via distinct transcriptomic and phenotypic transitions.
S Fortier, LRK Penke, D King, T Pham, G Ligresti, M Peters-Golden
JCI Insight, https://insight.jci.org/articles/view/14, 2021
542021
Alveolar epithelial cell–derived prostaglandin E2 serves as a request signal for macrophage secretion of suppressor of cytokine signaling 3 during innate inflammation
JM Speth, E Bourdonnay, LRK Penke, P Mancuso, BB Moore, ...
The Journal of Immunology 196 (12), 5112-5120, 2016
472016
Inhibition of IL-2 induced IL-10 production as a principle of phase-specific immunotherapy
M Bodas, N Jain, A Awasthi, S Martin, RK Penke Loka, D Dandekar, ...
The Journal of Immunology 177 (7), 4636-4643, 2006
462006
Resident Alveolar Macrophage-Derived Vesicular SOCS3 Dampens, but is Deficient in, Allergic Airway Inflammation.
C Draijer, JM Speth, LRK Penke, Z Zaslona, JD Bazzill, N Lugogo, ...
FASEB J., 2020
34*2020
Megakaryocytes compensate for Kit insufficiency in murine arthritis
P Cunin, LR Penke, JN Thon, PA Monach, T Jones, MH Chang, MM Chen, ...
The Journal of clinical investigation 127 (5), 1714-1724, 2017
332017
Molecular determinants of mesenchymal cell activation in fibroproliferative diseases
LR Penke, M Peters-Golden
Cell Mol Life Sci. 76 (21), 4179-4201, 2019
302019
Alveolar macrophage secretion of vesicular SOCS3 represents a platform for lung cancer therapeutics
JM Speth, LR Penke, JD Bazzill, KS Park, RG de Rubio, DJ Schneider, ...
JCI Insight. 2019 Oct 17;4(20). pii: 131340., 2019
282019
Antifibrotic factor KLF4 is repressed by the miR-10/TFAP2A/TBX5 axis in dermal fibroblasts: insights from twins discordant for systemic sclerosis
M Malaab, L Renaud, N Takamura, KD Zimmerman, WA da Silveira, ...
Annals of the rheumatic diseases 81 (2), 268-277, 2022
272022
Bortezomib Inhibits Lung Fibrosis and Fibroblast Activation Without Proteasome Inhibition
LRK Penke, J Speth, W Scott, D Christina, M Peters-Golden
The American Journal of Respiratory Cell and Molecular Biology 66 (1), 23-37., 2021
132021
Prostaglandin E2 receptors have differential effects on Leishmania major infection
LR Penke, R Sudan, S Sathishkumar, B Saha
Parasite immunology 35 (1), 51-54, 2013
132013
PGE2 accounts for bidirectional changes in alveolar macrophage self-renewal with aging and smoking
LR Penke, JM Speth, C Draijer, Z Zaslona, J Chen, P Mancuso, ...
Life Science Alliance 3 (11), 2020
122020
Alveolar Macrophage-Derived Extracellular Vesicles Inhibit Endosomal Fusion of Influenza Virus
DJ Schneider, KA Smith, CE Latuszek, CA Wilke, DM Lyons, LR Penke, ...
EMBO, 2020
112020
KLF4 is a therapeutically tractable brake on fibroblast activation that promotes resolution of pulmonary fibrosis
LR Penke, JM Speth, SK Huang, SM Fortier, J Baas, M Peters-Golden
JCI insight 7 (16), 2022
102022
Distinct PKA regulatory subunits mediate PGE2 inhibition of TGFβ-1-stimulated collagen I translation and myofibroblast differentiation.
SH Wettlaufer, LR Penke, K Okunishi, M Peters-Golden
Am J Physiol Lung Cell Mol Physiol. 313 (4), L722-L731., 2017
102017
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