Rintaro Hashizume
Rintaro Hashizume
Assistant Professor of Department of Pediatrics, Northwestern University, Ann & Robert H. Lurie
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Citata da
Citata da
Comprehensive characterization of cancer driver genes and mutations
MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ...
Cell 173 (2), 371-385. e18, 2018
The RING heterodimer BRCA1-BARD1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation
R Hashizume, M Fukuda, I Maeda, H Nishikawa, D Oyake, Y Yabuki, ...
Journal of Biological Chemistry 276 (18), 14537-14540, 2001
The histone H3. 3K27M mutation in pediatric glioma reprograms H3K27 methylation and gene expression
KM Chan, D Fang, H Gan, R Hashizume, C Yu, M Schroeder, N Gupta, ...
Genes & development 27 (9), 985-990, 2013
Pharmacologic inhibition of histone demethylation as a therapy for pediatric brainstem glioma
R Hashizume, N Andor, Y Ihara, R Lerner, H Gan, X Chen, D Fang, ...
Nature medicine 20 (12), 1394-1396, 2014
Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas
A Piunti, R Hashizume, MA Morgan, ET Bartom, CM Horbinski, ...
Nature medicine 23 (4), 493-500, 2017
Fascin, an actin-bundling protein associated with cell motility, is upregulated in hormone receptor negative breast cancer
A Grothey, R Hashizume, AA Sahin, PD McCrea
British journal of cancer 83 (7), 870-873, 2000
C-erbB-2/HER-2 upregulates fascin, an actin-bundling protein associated with cell motility, in human breast cancer cell lines
A Grothey, R Hashizume, H Ji, BE Tubb, CW Patrick, D Yu, EE Mooney, ...
Oncogene 19 (42), 4864-4875, 2000
New therapeutic approach for brain tumors: Intranasal delivery of telomerase inhibitor GRN163
R Hashizume, T Ozawa, SM Gryaznov, AW Bollen, KR Lamborn, WH Frey, ...
Neuro-oncology 10 (2), 112-120, 2008
Expression of epithelial cadherin and α‐and β‐catenins in nontumoral livers and hepatocellular carcinomas
A Ihara, H Koizumi, R Hashizume, T Uchikoshi
Hepatology 23 (6), 1441-1447, 1996
Targeted Therapy for BRAFV600E Malignant AstrocytomaTargeting BRAFV600E in Malignant Astrocytoma
TP Nicolaides, H Li, DA Solomon, S Hariono, R Hashizume, K Barkovich, ...
Clinical Cancer Research 17 (24), 7595-7604, 2011
DNA methylation profiling to predict recurrence risk in meningioma: development and validation of a nomogram to optimize clinical management
F Nassiri, Y Mamatjan, S Suppiah, JH Badhiwala, S Mansouri, S Karimi, ...
Neuro-oncology 21 (7), 901-910, 2019
Histone H3. 3K27M Represses p16 to Accelerate Gliomagenesis in a Murine Model of DIPGH3. 3K27M Cooperates with PDGF-B in Brainstem Gliomagenesis
FJ Cordero, Z Huang, C Grenier, X He, G Hu, RE McLendon, SK Murphy, ...
Molecular Cancer Research 15 (9), 1243-1254, 2017
Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy
L Wang, Z Zhao, PA Ozark, D Fantini, SA Marshall, EJ Rendleman, ...
Nature medicine 24 (6), 758-769, 2018
Expression of β‐catenin in normal breast tissue and breast carcinoma: a comparative study with epithelial cadherin and α‐catenin
R Hashizume, H Koizumi, A Ihara, T Ohta, T Uchikoshi
Histopathology 29 (2), 139-146, 1996
Targeting Wee1 for the treatment of pediatric high-grade gliomas
S Mueller, R Hashizume, X Yang, I Kolkowitz, AK Olow, J Phillips, ...
Neuro-oncology 16 (3), 352-360, 2014
Inhibition of DNA damage repair by the CDK4/6 inhibitor palbociclib delays irradiated intracranial atypical teratoid rhabdoid tumor and glioblastoma xenograft regrowth
R Hashizume, A Zhang, S Mueller, MD Prados, RR Lulla, S Goldman, ...
Neuro-oncology 18 (11), 1519-1528, 2016
Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy
E Huillard, R Hashizume, JJ Phillips, A Griveau, RA Ihrie, Y Aoki, ...
Proceedings of the National Academy of Sciences 109 (22), 8710-8715, 2012
Molecular and translational advances in meningiomas
S Suppiah, F Nassiri, WL Bi, IF Dunn, CO Hanemann, CM Horbinski, ...
Neuro-oncology 21 (Supplement_1), i4-i17, 2019
ACVR1 R206H cooperates with H3.1K27M in promoting diffuse intrinsic pontine glioma pathogenesis
CM Hoeman, FJ Cordero, G Hu, K Misuraca, MM Romero, HJ Cardona, ...
Nature communications 10 (1), 1023, 2019
Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics
X Huang, AM Dubuc, R Hashizume, J Berg, Y He, J Wang, C Chiang, ...
Genes & development 26 (16), 1780-1796, 2012
Il sistema al momento non pu eseguire l'operazione. Riprova pi tardi.
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