| Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions H Olzscha, SM Schermann, AC Woerner, S Pinkert, MH Hecht, ... Cell 144 (1), 67-78, 2011 | 702 | 2011 |
| ALS/FTD mutation-induced phase transition of FUS liquid droplets and reversible hydrogels into irreversible hydrogels impairs RNP granule function T Murakami, S Qamar, JQ Lin, GSK Schierle, E Rees, A Miyashita, ... Neuron 88 (4), 678-690, 2015 | 675 | 2015 |
| FUS phase separation is modulated by a molecular chaperone and methylation of arginine cation-π interactions S Qamar, GZ Wang, SJ Randle, FS Ruggeri, JA Varela, JQ Lin, ... Cell 173 (3), 720-734. e15, 2018 | 571 | 2018 |
| Prediction of aggregation-prone regions in structured proteins GG Tartaglia, AP Pawar, S Campioni, CM Dobson, F Chiti, M Vendruscolo Journal of molecular biology 380 (2), 425-436, 2008 | 484 | 2008 |
| Metastability of native proteins and the phenomenon of amyloid formation AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, ... Journal of the American Chemical Society 133 (36), 14160-14163, 2011 | 451 | 2011 |
| DnaK functions as a central hub in the E. coli chaperone network G Calloni, T Chen, SM Schermann, H Chang, P Genevaux, F Agostini, ... Cell reports 1 (3), 251-264, 2012 | 366 | 2012 |
| The Zyggregator method for predicting protein aggregation propensities GG Tartaglia, M Vendruscolo Chemical Society Reviews 37 (7), 1395-1401, 2008 | 333 | 2008 |
| Predicting protein associations with long noncoding RNAs M Bellucci, F Agostini, M Masin, GG Tartaglia Nature methods 8 (6), 444-445, 2011 | 330 | 2011 |
| Life on the edge: a link between gene expression levels and aggregation rates of human proteins GG Tartaglia, S Pechmann, CM Dobson, M Vendruscolo Trends in biochemical sciences 32 (5), 204-206, 2007 | 304 | 2007 |
| Widespread aggregation and neurodegenerative diseases are associated with supersaturated proteins P Ciryam, GG Tartaglia, RI Morimoto, CM Dobson, M Vendruscolo Cell reports 5 (3), 781-790, 2013 | 238 | 2013 |
| catRAPID omics: a web server for large-scale prediction of protein–RNA interactions F Agostini, A Zanzoni, P Klus, D Marchese, D Cirillo, GG Tartaglia Bioinformatics 29 (22), 2928-2930, 2013 | 229 | 2013 |
| Prediction of aggregation rate and aggregation‐prone segments in polypeptide sequences GG Tartaglia, A Cavalli, R Pellarin, A Caflisch Protein science 14 (10), 2723-2734, 2005 | 219 | 2005 |
| Systematic in vivo analysis of the intrinsic determinants of amyloid β pathogenicity LM Luheshi, GG Tartaglia, AC Brorsson, AP Pawar, IE Watson, F Chiti, ... PLoS biology 5 (11), e290, 2007 | 216 | 2007 |
| The role of aromaticity, exposed surface, and dipole moment in determining protein aggregation rates GG Tartaglia, A Cavalli, R Pellarin, A Caflisch Protein Science 13 (7), 1939-1941, 2004 | 188 | 2004 |
| A concentration-dependent liquid phase separation can cause toxicity upon increased protein expression B Bolognesi, NL Gotor, R Dhar, D Cirillo, M Baldrighi, GG Tartaglia, ... Cell reports 16 (1), 222-231, 2016 | 183 | 2016 |
| Physicochemical principles that regulate the competition between functional and dysfunctional association of proteins S Pechmann, ED Levy, GG Tartaglia, M Vendruscolo Proceedings of the National Academy of Sciences 106 (25), 10159-10164, 2009 | 167 | 2009 |
| Amyloid formation by the pro-inflammatory S100A8/A9 proteins in the ageing prostate K Yanamandra, O Alexeyev, V Zamotin, V Srivastava, A Shchukarev, ... PloS one 4 (5), e5562, 2009 | 131 | 2009 |
| Sequence-based prediction of protein solubility F Agostini, M Vendruscolo, GG Tartaglia Journal of molecular biology 421 (2-3), 237-241, 2012 | 115 | 2012 |
| Molecular determinants of the aggregation behavior of α‐and β‐synuclein RC Rivers, JR Kumita, GG Tartaglia, MM Dedmon, A Pawar, ... Protein Science 17 (5), 887-898, 2008 | 115 | 2008 |
| ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism T Murakami, SP Yang, L Xie, T Kawano, D Fu, A Mukai, C Bohm, F Chen, ... Human molecular genetics 21 (1), 1-9, 2012 | 111 | 2012 |
Michele VendruscoloProfessor of Biophysics, University of CambridgeVerified email at cam.ac.uk
