gian gaetano tartaglia
gian gaetano tartaglia
Centre for Genomic Regulation & ICREA (University of Cambridge, University of Zurich, La Sapienza)
Verified email at crg.es - Homepage
TitleCited byYear
Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions
H Olzscha, SM Schermann, AC Woerner, S Pinkert, MH Hecht, ...
Cell 144 (1), 67-78, 2011
4632011
Prediction of aggregation-prone regions in structured proteins
GG Tartaglia, AP Pawar, S Campioni, CM Dobson, F Chiti, M Vendruscolo
Journal of molecular biology 380 (2), 425-436, 2008
3982008
Metastability of native proteins and the phenomenon of amyloid formation
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, ...
Journal of the American Chemical Society 133 (36), 14160-14163, 2011
2652011
The Zyggregator method for predicting protein aggregation propensities
GG Tartaglia, M Vendruscolo
Chemical Society Reviews 37 (7), 1395-1401, 2008
2312008
ALS/FTD mutation-induced phase transition of FUS liquid droplets and reversible hydrogels into irreversible hydrogels impairs RNP granule function
T Murakami, S Qamar, JQ Lin, GSK Schierle, E Rees, A Miyashita, ...
Neuron 88 (4), 678-690, 2015
2192015
Life on the edge: a link between gene expression levels and aggregation rates of human proteins
GG Tartaglia, S Pechmann, CM Dobson, M Vendruscolo
Trends in biochemical sciences 32 (5), 204-206, 2007
2162007
DnaK functions as a central hub in the E. coli chaperone network
G Calloni, T Chen, SM Schermann, H Chang, P Genevaux, F Agostini, ...
Cell reports 1 (3), 251-264, 2012
2012012
Predicting protein associations with long noncoding RNAs
M Bellucci, F Agostini, M Masin, GG Tartaglia
Nature methods 8 (6), 444, 2011
1922011
Systematic in vivo analysis of the intrinsic determinants of amyloid β pathogenicity
LM Luheshi, GG Tartaglia, AC Brorsson, AP Pawar, IE Watson, F Chiti, ...
PLoS biology 5 (11), e290, 2007
1842007
Prediction of aggregation rate and aggregation‐prone segments in polypeptide sequences
GG Tartaglia, A Cavalli, R Pellarin, A Caflisch
Protein Science 14 (10), 2723-2734, 2005
1772005
The role of aromaticity, exposed surface, and dipole moment in determining protein aggregation rates
GG Tartaglia, A Cavalli, R Pellarin, A Caflisch
Protein Science 13 (7), 1939-1941, 2004
1542004
Widespread aggregation and neurodegenerative diseases are associated with supersaturated proteins
P Ciryam, GG Tartaglia, RI Morimoto, CM Dobson, M Vendruscolo
Cell reports 5 (3), 781-790, 2013
1282013
Physicochemical principles that regulate the competition between functional and dysfunctional association of proteins
S Pechmann, ED Levy, GG Tartaglia, M Vendruscolo
Proceedings of the National Academy of Sciences 106 (25), 10159-10164, 2009
1262009
Amyloid formation by the pro-inflammatory S100A8/A9 proteins in the ageing prostate
K Yanamandra, O Alexeyev, V Zamotin, V Srivastava, A Shchukarev, ...
PloS one 4 (5), e5562, 2009
952009
catRAPID omics: a web server for large-scale prediction of protein–RNA interactions
F Agostini, A Zanzoni, P Klus, D Marchese, D Cirillo, GG Tartaglia
Bioinformatics 29 (22), 2928-2930, 2013
942013
Molecular determinants of the aggregation behavior of α‐and β‐synuclein
RC Rivers, JR Kumita, GG Tartaglia, MM Dedmon, A Pawar, ...
Protein Science 17 (5), 887-898, 2008
912008
Characterisation of amyloid fibril formation by small heat-shock chaperone proteins human αA-, αB-and R120G αB-crystallins
S Meehan, TPJ Knowles, AJ Baldwin, JF Smith, AM Squires, P Clements, ...
Journal of molecular biology 372 (2), 470-484, 2007
882007
Sequence-based prediction of protein solubility
F Agostini, M Vendruscolo, GG Tartaglia
Journal of molecular biology 421 (2-3), 237-241, 2012
792012
Competition between intramolecular and intermolecular interactions in an amyloid-forming protein
KE Routledge, GG Tartaglia, GW Platt, M Vendruscolo, SE Radford
Journal of molecular biology 389 (4), 776-786, 2009
742009
ALS mutations in FUS cause neuronal dysfunction and death in Caenorhabditis elegans by a dominant gain-of-function mechanism
T Murakami, SP Yang, L Xie, T Kawano, D Fu, A Mukai, C Bohm, F Chen, ...
Human molecular genetics 21 (1), 1-9, 2011
722011
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