gian gaetano tartaglia
gian gaetano tartaglia
CRG / ICREA / Sapienza (IIT, University of Cambridge / University of Zurich)
Verified email at tartaglialab.com - Homepage
TitleCited byYear
Amyloid-like aggregates sequester numerous metastable proteins with essential cellular functions
H Olzscha, SM Schermann, AC Woerner, S Pinkert, MH Hecht, ...
Cell 144 (1), 67-78, 2011
5062011
Prediction of aggregation-prone regions in structured proteins
GG Tartaglia, AP Pawar, S Campioni, CM Dobson, F Chiti, M Vendruscolo
Journal of molecular biology 380 (2), 425-436, 2008
4122008
Metastability of native proteins and the phenomenon of amyloid formation
AJ Baldwin, TPJ Knowles, GG Tartaglia, AW Fitzpatrick, GL Devlin, ...
Journal of the American Chemical Society 133 (36), 14160-14163, 2011
3022011
ALS/FTD mutation-induced phase transition of FUS liquid droplets and reversible hydrogels into irreversible hydrogels impairs RNP granule function
T Murakami, S Qamar, JQ Lin, GSK Schierle, E Rees, A Miyashita, ...
Neuron 88 (4), 678-690, 2015
2832015
The Zyggregator method for predicting protein aggregation propensities
GG Tartaglia, M Vendruscolo
Chemical Society Reviews 37 (7), 1395-1401, 2008
2512008
Life on the edge: a link between gene expression levels and aggregation rates of human proteins
GG Tartaglia, S Pechmann, CM Dobson, M Vendruscolo
Trends in biochemical sciences 32 (5), 204-206, 2007
2292007
DnaK functions as a central hub in the E. coli chaperone network
G Calloni, T Chen, SM Schermann, H Chang, P Genevaux, F Agostini, ...
Cell reports 1 (3), 251-264, 2012
2232012
Predicting protein associations with long noncoding RNAs
M Bellucci, F Agostini, M Masin, GG Tartaglia
Nature methods 8 (6), 444, 2011
2212011
Systematic in vivo analysis of the intrinsic determinants of amyloid β pathogenicity
LM Luheshi, GG Tartaglia, AC Brorsson, AP Pawar, IE Watson, F Chiti, ...
PLoS biology 5 (11), e290, 2007
1912007
Prediction of aggregation rate and aggregation‐prone segments in polypeptide sequences
GG Tartaglia, A Cavalli, R Pellarin, A Caflisch
Protein Science 14 (10), 2723-2734, 2005
1852005
The role of aromaticity, exposed surface, and dipole moment in determining protein aggregation rates
GG Tartaglia, A Cavalli, R Pellarin, A Caflisch
Protein Science 13 (7), 1939-1941, 2004
1592004
Widespread aggregation and neurodegenerative diseases are associated with supersaturated proteins
P Ciryam, GG Tartaglia, RI Morimoto, CM Dobson, M Vendruscolo
Cell reports 5 (3), 781-790, 2013
1452013
Physicochemical principles that regulate the competition between functional and dysfunctional association of proteins
S Pechmann, ED Levy, GG Tartaglia, M Vendruscolo
Proceedings of the National Academy of Sciences 106 (25), 10159-10164, 2009
1342009
catRAPID omics: a web server for large-scale prediction of protein–RNA interactions
F Agostini, A Zanzoni, P Klus, D Marchese, D Cirillo, GG Tartaglia
Bioinformatics 29 (22), 2928-2930, 2013
1132013
FUS phase separation is modulated by a molecular chaperone and methylation of arginine cation-π interactions
S Qamar, GZ Wang, SJ Randle, FS Ruggeri, JA Varela, JQ Lin, ...
Cell 173 (3), 720-734. e15, 2018
1042018
Amyloid formation by the pro-inflammatory S100A8/A9 proteins in the ageing prostate
K Yanamandra, O Alexeyev, V Zamotin, V Srivastava, A Shchukarev, ...
PloS one 4 (5), e5562, 2009
1042009
Molecular determinants of the aggregation behavior of α‐and β‐synuclein
RC Rivers, JR Kumita, GG Tartaglia, MM Dedmon, A Pawar, ...
Protein Science 17 (5), 887-898, 2008
942008
Characterisation of amyloid fibril formation by small heat-shock chaperone proteins human αA-, αB-and R120G αB-crystallins
S Meehan, TPJ Knowles, AJ Baldwin, JF Smith, AM Squires, P Clements, ...
Journal of molecular biology 372 (2), 470-484, 2007
892007
Sequence-based prediction of protein solubility
F Agostini, M Vendruscolo, GG Tartaglia
Journal of molecular biology 421 (2-3), 237-241, 2012
872012
Competition between intramolecular and intermolecular interactions in an amyloid-forming protein
KE Routledge, GG Tartaglia, GW Platt, M Vendruscolo, SE Radford
Journal of molecular biology 389 (4), 776-786, 2009
772009
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