Serial quantitative TSPO-targeted PET reveals peak microglial activation up to 2 weeks after an epileptogenic brain insult M Brackhan, P Bascuñana, JM Postema, TL Ross, FM Bengel, ... Journal of Nuclear Medicine 57 (8), 1302-1308, 2016 | 60 | 2016 |
Fingolimod as a treatment in neurologic disorders beyond multiple sclerosis P Bascuñana, L Möhle, M Brackhan, J Pahnke Drugs in R&D 20, 197-207, 2020 | 35 | 2020 |
French maritime pine bark treatment decelerates plaque development and improves spatial memory in Alzheimer's disease mice K Paarmann, SR Prakash, M Krohn, L Möhle, M Brackhan, T Brüning, ... Phytomedicine 57, 39-48, 2019 | 25 | 2019 |
Imaging P-Glycoprotein Induction at the Blood–Brain Barrier of a β-Amyloidosis Mouse Model with 11C-Metoclopramide PET V Zoufal, S Mairinger, M Brackhan, M Krohn, T Filip, M Sauberer, J Stanek, ... Journal of Nuclear Medicine 61 (7), 1050-1057, 2020 | 24 | 2020 |
[18F]GE180 positron emission tomographic imaging indicates a potential double‐hit insult in the intrahippocampal kainate mouse model of temporal lobe epilepsy M Brackhan, P Bascuñana, TL Ross, FM Bengel, JP Bankstahl, ... Epilepsia 59 (3), 617-626, 2018 | 24 | 2018 |
Strategies to gain novel Alzheimer’s disease diagnostics and therapeutics using modulators of ABCA transporters J Pahnke, P Bascuñana, M Brackhan, K Stefan, V Namasivayam, ... Free neuropathology 2, 2021 | 17 | 2021 |
Development of deep learning models for microglia analyses in brain tissue using DeePathology™ STUDIO L Möhle, P Bascunana, M Brackhan, J Pahnke Journal of neuroscience methods 364, 109371, 2021 | 15 | 2021 |
Divergent metabolic substrate utilization in brain during epileptogenesis precedes chronic hypometabolism P Bascuñana, M Brackhan, I Leiter, H Keller, I Jahreis, TL Ross, ... Journal of Cerebral Blood Flow & Metabolism 40 (1), 204-213, 2020 | 15 | 2020 |
Dimethyl fumarate does not mitigate cognitive decline and β-amyloidosis in female APPPS1 mice L Möhle, M Brackhan, P Bascunana, J Pahnke Brain Research 1768, 147579, 2021 | 14 | 2021 |
Machine learning-supported analyses improve quantitative histological assessments of amyloid-β deposits and activated microglia P Bascuñana, M Brackhan, J Pahnke Journal of Alzheimer's Disease 79 (2), 597-605, 2021 | 13 | 2021 |
TSPO PET identifies different anti-inflammatory minocycline treatment response in two rodent models of epileptogenesis BJ Wolf, M Brackhan, P Bascuñana, I Leiter, BLN Langer, TL Ross, ... Neurotherapeutics 17 (3), 1228-1238, 2020 | 13 | 2020 |
99mTc-HMPAO SPECT imaging reveals brain hypoperfusion during status epilepticus P Bascuñana, BJ Wolf, I Jahreis, M Brackhan, L García-García, TL Ross, ... Metabolic brain disease 36, 2597-2602, 2021 | 7 | 2021 |
Generation and characterization of an Abcc1 humanized mouse model (hABCC1flx/flx) with knockout capability M Krohn, V Zoufal, S Mairinger, T Wanek, K Paarmann, T Brüning, I Eiriz, ... Molecular pharmacology 96 (2), 138-147, 2019 | 7 | 2019 |
Isotope‐labeled amyloid‐β does not transmit to the brain in a prion‐like manner after peripheral administration M Brackhan, G Calza, K Lundgren, P Bascunana, T Brüning, R Soliymani, ... EMBO reports 23 (7), e54405, 2022 | 6 | 2022 |
Brain distribution of dual ABCB1/ABCG2 substrates is unaltered in a beta-amyloidosis mouse model T Wanek, V Zoufal, M Brackhan, M Krohn, S Mairinger, T Filip, M Sauberer, ... International Journal of Molecular Sciences 21 (21), 8245, 2020 | 6 | 2020 |
ABC transporter C1 prevents dimethyl fumarate from targeting Alzheimer’s disease L Möhle, K Stefan, P Bascuñana, M Brackhan, T Brüning, I Eiriz, ... Biology 12 (7), 932, 2023 | 5 | 2023 |
Time-and sex-dependent effects of fingolimod treatment in a mouse model of alzheimer’s disease P Bascuñana, M Brackhan, L Möhle, J Wu, T Brüning, I Eiriz, B Jansone, ... Biomolecules 13 (2), 331, 2023 | 5 | 2023 |
Aging, NRF2, and TAU: A Perfect Match for Neurodegeneration? M Brackhan, M Arribas-Blazquez, I Lastres-Becker Antioxidants 12 (8), 1564, 2023 | 4 | 2023 |
Detection and Prediction of Mild Cognitive Impairment in Alzheimer’s Disease Mice SP Rai, P Bascuñana, M Brackhan, M Krohn, L Möhle, K Paarmann, ... Journal of Alzheimer's Disease 77 (3), 1209-1221, 2020 | 4 | 2020 |
A New Tool for the Analysis of the Effect of Intracerebrally Injected Anti-Amyloid-β Compounds J Upīte, T Brüning, L Möhle, M Brackhan, P Bascuñana, B Jansone, ... Journal of Alzheimer's Disease 84 (4), 1677-1690, 2021 | 3 | 2021 |