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D'Orazi Gabriella
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
12775*2021
Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies
G Pistritto, D Trisciuoglio, C Ceci, A Garufi, G D'Orazi
Aging (albany NY) 8 (4), 603, 2016
13512016
Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis
G D'Orazi, B Cecchinelli, T Bruno, I Manni, Y Higashimoto, S Saito, ...
Nature cell biology 4 (1), 11-19, 2002
8472002
Type IV collagenase (s) and TIMPs modulate endothelial cell morphogenesis in vitro
HW Schnaper, DS Grant, WG Stetler‐Stevenson, R Fridman, G D'Orazi, ...
Journal of cellular physiology 156 (2), 235-246, 1993
3651993
Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways
M Granato, C Rizzello, MSG Montani, L Cuomo, M Vitillo, R Santarelli, ...
The Journal of nutritional biochemistry 41, 124-136, 2017
1942017
Regulation of p53 activity by HIPK2: molecular mechanisms and therapeutical implications in human cancer cells
R Puca, L Nardinocchi, D Givol, G D'orazi
Oncogene 29 (31), 4378-4387, 2010
1742010
Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs
R Puca, L Nardinocchi, M Porru, AJ Simon, G Rechavi, C Leonetti, D Givol, ...
Cell cycle 10 (10), 1679-1689, 2011
1272011
Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo
L Nardinocchi, V Pantisano, R Puca, M Porru, A Aiello, A Grasselli, ...
PloS one 5 (12), e15048, 2010
1212010
Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis
V Di Stefano, C Rinaldo, A Sacchi, S Soddu, G D'Orazi
Experimental cell research 293 (2), 311-320, 2004
1202004
Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis
L Nardinocchi, R Puca, A Sacchi, G D'Orazi
Molecular cancer 8, 1-9, 2009
1172009
HIPK2 modulates p53 activity towards pro-apoptotic transcription
R Puca, L Nardinocchi, A Sacchi, G Rechavi, D Givol, G D'Orazi
Molecular cancer 8 (1), 1-14, 2009
982009
HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function
VD Stefano, G Blandino, A Sacchi, S Soddu, G D'Orazi
Oncogene 23 (30), 5185-5192, 2004
942004
Updates on HIPK2: a resourceful oncosuppressor for clearing cancer
G D’Orazi, C Rinaldo, S Soddu
Journal of Experimental & Clinical Cancer Research 31 (1), 1-8, 2012
882012
HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage
V Di Stefano, S Soddu, A Sacchi, G D'Orazi
Oncogene 24 (35), 5431-5442, 2005
882005
Degradation of mutant p53H175 protein by Zn (II) through autophagy
A Garufi, D Pucci, V D’Orazi, M Cirone, G Bossi, ML Avantaggiati, ...
Cell death & disease 5 (5), e1271-e1271, 2014
862014
Localization of type IV and V collagens in the stroma of human amnion
A Modesti, S Scarpa, G D'Orazi, L Simonelli, FG Caramia
Progress in clinical and biological research 296, 459-463, 1989
851989
Histone deacetylase inhibitors VPA and TSA induce apoptosis and autophagy in pancreatic cancer cells
MS Gilardini Montani, M Granato, C Santoni, P Del Porto, N Merendino, ...
Cellular Oncology 40, 167-180, 2017
842017
A fluorescent curcumin-based Zn (II)-complex reactivates mutant (R175H and R273H) p53 in cancer cells
A Garufi, D Trisciuoglio, M Porru, C Leonetti, A Stoppacciaro, V D’Orazi, ...
Journal of Experimental & Clinical Cancer Research 32, 1-11, 2013
822013
HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma
M Granato, V Lacconi, M Peddis, LV Lotti, L Di Renzo, R Gonnella, ...
Cell death & disease 4 (7), e730-e730, 2013
822013
Reversible dysfunction of wild-type p53 following homeodomain-interacting protein kinase-2 knockdown
R Puca, L Nardinocchi, H Gal, G Rechavi, N Amariglio, E Domany, ...
Cancer research 68 (10), 3707-3714, 2008
822008
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