| Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1-382, 2021 | 9381 | 2021 |
| Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategies G Pistritto, D Trisciuoglio, C Ceci, A Garufi, G D'Orazi Aging (Albany NY) 8 (4), 603, 2016 | 1060 | 2016 |
| Homeodomain-interacting protein kinase-2 phosphorylates p53 at Ser 46 and mediates apoptosis G D'Orazi, B Cecchinelli, T Bruno, I Manni, Y Higashimoto, S Saito, ... Nature cell biology 4 (1), 11-19, 2002 | 823 | 2002 |
| Type IV collagenase (s) and TIMPs modulate endothelial cell morphogenesis in vitro HW Schnaper, DS Grant, WG Stetler‐Stevenson, R Fridman, G D'Orazi, ... Journal of cellular physiology 156 (2), 235-246, 1993 | 359 | 1993 |
| Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways M Granato, C Rizzello, MSG Montani, L Cuomo, M Vitillo, R Santarelli, ... The Journal of nutritional biochemistry 41, 124-136, 2017 | 162 | 2017 |
| Regulation of p53 activity by HIPK2: molecular mechanisms and therapeutical implications in human cancer cells R Puca, L Nardinocchi, D Givol, G D'orazi Oncogene 29 (31), 4378-4387, 2010 | 160 | 2010 |
| Inhibition of HIF-1alpha activity by homeodomain-interacting protein kinase-2 correlates with sensitization of chemoresistant cells to undergo apoptosis L Nardinocchi, R Puca, A Sacchi, G D'Orazi Molecular cancer 8, 1-9, 2009 | 120 | 2009 |
| Homeodomain-interacting protein kinase-2 activity and p53 phosphorylation are critical events for cisplatin-mediated apoptosis V Di Stefano, C Rinaldo, A Sacchi, S Soddu, G D'Orazi Experimental cell research 293 (2), 311-320, 2004 | 118 | 2004 |
| Restoring p53 active conformation by zinc increases the response of mutant p53 tumor cells to anticancer drugs R Puca, L Nardinocchi, M Porru, AJ Simon, G Rechavi, C Leonetti, D Givol, ... Cell cycle 10 (10), 1679-1689, 2011 | 115 | 2011 |
| Zinc downregulates HIF-1α and inhibits its activity in tumor cells in vitro and in vivo L Nardinocchi, V Pantisano, R Puca, M Porru, A Aiello, A Grasselli, ... PloS one 5 (12), e15048, 2010 | 105 | 2010 |
| HIPK2 neutralizes MDM2 inhibition rescuing p53 transcriptional activity and apoptotic function VD Stefano, G Blandino, A Sacchi, S Soddu, G D'Orazi Oncogene 23 (30), 5185-5192, 2004 | 92 | 2004 |
| HIPK2 modulates p53 activity towards pro-apoptotic transcription R Puca, L Nardinocchi, A Sacchi, G Rechavi, D Givol, G D'Orazi Molecular cancer 8 (1), 1-14, 2009 | 90 | 2009 |
| HIPK2 contributes to PCAF-mediated p53 acetylation and selective transactivation of p21Waf1 after nonapoptotic DNA damage V Di Stefano, S Soddu, A Sacchi, G D'Orazi Oncogene 24 (35), 5431-5442, 2005 | 87 | 2005 |
| Localization of type IV and V collagens in the stroma of human amnion A Modesti, S Scarpa, G D'Orazi, L Simonelli, FG Caramia Progress in clinical and biological research 296, 459-463, 1989 | 82 | 1989 |
| HSP70 inhibition by 2-phenylethynesulfonamide induces lysosomal cathepsin D release and immunogenic cell death in primary effusion lymphoma M Granato, V Lacconi, M Peddis, LV Lotti, L Di Renzo, R Gonnella, ... Cell death & disease 4 (7), e730-e730, 2013 | 79 | 2013 |
| Updates on HIPK2: a resourceful oncosuppressor for clearing cancer G D’Orazi, C Rinaldo, S Soddu Journal of Experimental & Clinical Cancer Research 31 (1), 1-8, 2012 | 79 | 2012 |
| Reversible dysfunction of wild-type p53 following homeodomain-interacting protein kinase-2 knockdown R Puca, L Nardinocchi, H Gal, G Rechavi, N Amariglio, E Domany, ... Cancer research 68 (10), 3707-3714, 2008 | 78 | 2008 |
| Degradation of mutant p53H175 protein by Zn (II) through autophagy A Garufi, D Pucci, V D’Orazi, M Cirone, G Bossi, ML Avantaggiati, ... Cell death & disease 5 (5), e1271-e1271, 2014 | 76 | 2014 |
| SLC25A1, or CIC, is a novel transcriptional target of mutant p53 and a negative tumor prognostic marker VK Kolukula, G Sahu, A Wellstein, OC Rodriguez, A Preet, V Iacobazzi, ... Oncotarget 5 (5), 1212, 2014 | 74 | 2014 |
| Nox1 is involved in p53 deacetylation and suppression of its transcriptional activity and apoptosis R Puca, L Nardinocchi, G Starace, G Rechavi, A Sacchi, D Givol, ... Free Radical Biology and Medicine 48 (10), 1338-1346, 2010 | 72 | 2010 |
Silvia SodduRegina Elena Cancer InstituteVerified email at ifo.gov.it
