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Prof David Selwood
Prof David Selwood
Professor of Medicinal Chemistry, UCL
Verified email at ucl.ac.uk
Title
Cited by
Cited by
Year
HIV-1 evades innate immune recognition through specific cofactor recruitment
J Rasaiyaah, CP Tan, AJ Fletcher, AJ Price, C Blondeau, L Hilditch, ...
Nature 503 (7476), 402-405, 2013
5142013
Disruption of methylarginine metabolism impairs vascular homeostasis
J Leiper, M Nandi, B Torondel, J Murray-Rust, M Malaki, B O'Hara, ...
Nature medicine 13 (2), 198-203, 2007
4782007
Two‐and three‐dimensional rings in drugs
M Aldeghi, S Malhotra, DL Selwood, AWE Chan
Chemical biology & drug design 83 (4), 450-461, 2014
2852014
Small molecule inhibitors of the neuropilin-1 vascular endothelial growth factor A (VEGF-A) interaction
A Jarvis, CK Allerston, H Jia, B Herzog, A Garza-Garcia, N Winfield, ...
Journal of medicinal chemistry 53 (5), 2215-2226, 2010
2012010
Synthesis and biological evaluation of novel pyrazoles and indazoles as activators of the nitric oxide receptor, soluble guanylate cyclase
DL Selwood, DG Brummell, J Budworth, GE Burtin, RO Campbell, ...
Journal of medicinal chemistry 44 (1), 78-93, 2001
1682001
Characterization of a bicyclic peptide neuropilin-1 (NP-1) antagonist (EG3287) reveals importance of vascular endothelial growth factor exon 8 for NP-1 binding and role of NP-1 …
H Jia, A Bagherzadeh, B Hartzoulakis, A Jarvis, M Lohr, S Shaikh, R Aqil, ...
Journal of Biological Chemistry 281 (19), 13493-13502, 2006
1672006
Structure-activity relationships of antifilarial antimycin analogs: a multivariate pattern recognition study
DL Selwood, DJ Livingstone, JCW Comley, AB O'Dowd, AT Hudson, ...
Journal of medicinal chemistry 33 (1), 136-142, 1990
1671990
Mitochondrial permeability transition: a molecular lesion with multiple drug targets
T Briston, DL Selwood, G Szabadkai, MR Duchen
Trends in pharmacological sciences 40 (1), 50-70, 2019
1642019
Endothelial C-type natriuretic peptide maintains vascular homeostasis
AJ Moyes, RS Khambata, I Villar, KJ Bubb, RS Baliga, NG Lumsden, ...
The Journal of clinical investigation 124 (9), 4039-4051, 2014
1582014
Is multiple sclerosis a length-dependent central axonopathy? The case for therapeutic lag and the asynchronous progressive MS hypotheses
G Giovannoni, G Cutter, MP Sormani, S Belachew, R Hyde, H Koendgen, ...
Multiple sclerosis and related disorders 12, 70-78, 2017
1182017
Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity
H Jia, L Cheng, M Tickner, A Bagherzadeh, D Selwood, I Zachary
British journal of cancer 102 (3), 541-552, 2010
1162010
Small-molecule mimics of an α-helix for efficient transport of proteins into cells
M Okuyama, H Laman, SR Kingsbury, C Visintin, E Leo, KL Eward, ...
Nature Methods 4 (2), 153-159, 2007
1052007
siRNA delivery: from lipids to cell‐penetrating peptides and their mimics
M Gooding, LP Browne, FM Quinteiro, DL Selwood
Chemical biology & drug design 80 (6), 787-809, 2012
1012012
Motionless volumetric photoacoustic microscopy with spatially invariant resolution
J Yang, L Gong, X Xu, P Hai, Y Shen, Y Suzuki, LV Wang
Nature communications 8 (1), 780, 2017
982017
Selective inhibition of the mitochondrial permeability transition pore protects against neurodegeneration in experimental multiple sclerosis
J Warne, G Pryce, JM Hill, X Shi, F Lennerås, F Puentes, M Kip, L Hilditch, ...
Journal of Biological Chemistry 291 (9), 4356-4373, 2016
952016
Gyrase B inhibitor impairs HIV-1 replication by targeting Hsp90 and the capsid protein
L Vozzolo, B Loh, PJ Gane, M Tribak, L Zhou, I Anderson, E Nyakatura, ...
Journal of biological chemistry 285 (50), 39314-39328, 2010
942010
Aurora A and B kinases as targets for cancer: will they be selective for tumors?
N Matthews, C Visintin, B Hartzoulakis, A Jarvis, DL Selwood
Expert review of anticancer therapy 6 (1), 109-120, 2006
912006
Imatinib binding and cKIT inhibition is abrogated by the cKIT kinase domain I missense mutation Val654Ala
SR McLean, M Gana-Weisz, B Hartzoulakis, R Frow, J Whelan, ...
Molecular cancer therapeutics 4 (12), 2008-2015, 2005
902005
Peptides encoded by exon 6 of VEGF inhibit endothelial cell biological responses and angiogenesis induced by VEGF
H Jia, S Jezequel, M Löhr, S Shaikh, D Davis, S Soker, D Selwood, ...
Biochemical and biophysical research communications 283 (1), 164-173, 2001
872001
Cysteine-rich and basic domain HIV-1 Tat peptides inhibit angiogenesis and induce endothelial cell apoptosis
H Jia, M Lohr, S Jezequel, D Davis, S Shaikh, D Selwood, I Zachary
Biochemical and biophysical research communications 283 (2), 469-479, 2001
852001
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