Defective suppressor function in CD4+ CD25+ T-cells from patients with type 1 diabetes S Lindley, CM Dayan, A Bishop, BO Roep, M Peakman, TIM Tree Diabetes 54 (1), 92-99, 2005 | 1142 | 2005 |
Autoreactive T cell responses show proinflammatory polarization in diabetes but a regulatory phenotype in health S Arif, TI Tree, TP Astill, JM Tremble, AJ Bishop, CM Dayan, BO Roep, ... The Journal of clinical investigation 113 (3), 451-463, 2004 | 584 | 2004 |
A single autoimmune T cell receptor recognizes more than a million different peptides L Wooldridge, J Ekeruche-Makinde, H Van Den Berg, A Skowera, ... Journal of Biological Chemistry 287 (2), 1168-1177, 2012 | 498 | 2012 |
CTLs are targeted to kill β cells in patients with type 1 diabetes through recognition of a glucose-regulated preproinsulin epitope A Skowera, RJ Ellis, R Varela-Calviño, S Arif, GC Huang, C Van-Krinks, ... The Journal of clinical investigation 118 (10), 3390-3402, 2008 | 455 | 2008 |
Translational mini-review series on type 1 diabetes: systematic analysis of T cell epitopes in autoimmune diabetes TP Di Lorenzo, M Peakman, BO Roep Clinical & Experimental Immunology 148 (1), 1-16, 2007 | 312 | 2007 |
Antigen targets of type 1 diabetes autoimmunity BO Roep, M Peakman Cold Spring Harbor perspectives in medicine 2 (4), a007781, 2012 | 304 | 2012 |
Elevated serum levels of macrophage-derived cytokines precede and accompany the onset of IDDM MJ Hussain, M Peakman, H Gallati, SSS Lo, M Hawa, GC Viberti, ... Diabetologia 39, 60-69, 1996 | 299 | 1996 |
Resident CD141 (BDCA3)+ dendritic cells in human skin produce IL-10 and induce regulatory T cells that suppress skin inflammation CC Chu, N Ali, P Karagiannis, P Di Meglio, A Skowera, L Napolitano, ... Journal of Experimental Medicine 209 (5), 935-945, 2012 | 298 | 2012 |
Peripheral and islet interleukin-17 pathway activation characterizes human autoimmune diabetes and promotes cytokine-mediated β-cell death S Arif, F Moore, K Marks, T Bouckenooghe, CM Dayan, R Planas, ... Diabetes 60 (8), 2112-2119, 2011 | 262 | 2011 |
Blood and islet phenotypes indicate immunological heterogeneity in type 1 diabetes S Arif, P Leete, V Nguyen, K Marks, NM Nor, M Estorninho, ... Diabetes 63 (11), 3835-3845, 2014 | 233 | 2014 |
Simultaneous detection of circulating autoreactive CD8+ T-cells specific for different islet cell–associated epitopes using combinatorial MHC multimers JH Velthuis, WW Unger, JRF Abreu, G Duinkerken, K Franken, ... Diabetes 59 (7), 1721-1730, 2010 | 225 | 2010 |
Increased resistance to CD4+CD25hi regulatory T cell-mediated suppression in patients with type 1 diabetes JM Lawson, J Tremble, C Dayan, H Beyan, RDG Leslie, M Peakman, ... Clinical & Experimental Immunology 154 (3), 353-359, 2008 | 220 | 2008 |
Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes AM Bulek, DK Cole, A Skowera, G Dolton, S Gras, F Madura, A Fuller, ... Nature immunology 13 (3), 283-289, 2012 | 213 | 2012 |
Prevalence of anti-N-methyl-d-aspartate (NMDA) receptor antibodies in patients with schizophrenia and related psychoses: a systematic review and meta-analysis TA Pollak, R McCormack, M Peakman, TR Nicholson, AS David Psychological medicine 44 (12), 2475-2487, 2014 | 199 | 2014 |
Costimulation modulation with abatacept in patients with recent-onset type 1 diabetes: follow-up 1 year after cessation of treatment T Orban, B Bundy, DJ Becker, LA DiMeglio, SE Gitelman, R Goland, ... Diabetes care 37 (4), 1069-1075, 2014 | 199 | 2014 |
Posttranslational modification of HLA-DQ binding islet autoantigens in type 1 diabetes M Van Lummel, G Duinkerken, PA Van Veelen, A De Ru, R Cordfunke, ... Diabetes 63 (1), 237-247, 2014 | 187 | 2014 |
Translational mini-review series on type 1 diabetes: immune-based therapeutic approaches for type 1 diabetes T Staeva-Vieira, M Peakman, M Von Herrath Clinical & Experimental Immunology 148 (1), 17-31, 2007 | 183 | 2007 |
Protein kinase inhibitors substantially improve the physical detection of T-cells with peptide-MHC tetramers A Lissina, K Ladell, A Skowera, M Clement, E Edwards, R Seggewiss, ... Journal of immunological methods 340 (1), 11-24, 2009 | 181 | 2009 |
Proinsulin peptide immunotherapy in type 1 diabetes: report of a first-in-man Phase I safety study SL Thrower, L James, W Hall, KM Green, S Arif, JS Allen, C Van-Krinks, ... Clinical & Experimental Immunology 155 (2), 156-165, 2009 | 179 | 2009 |
A systematic review and critical evaluation of the immunology of chronic fatigue syndrome M Lyall, M Peakman, S Wessely Journal of psychosomatic research 55 (2), 79-90, 2003 | 172 | 2003 |