Epigenetic reprogramming of cancer cells via targeted DNA methylation AG Rivenbark, S Stolzenburg, AS Beltran, X Yuan, MG Rots, BD Strahl, ... Epigenetics 7 (4), 350-360, 2012 | 236 | 2012 |
Inhibition of lapatinib-induced kinome reprogramming in ERBB2-positive breast cancer by targeting BET family bromodomains TJ Stuhlmiller, SM Miller, JS Zawistowski, K Nakamura, AS Beltran, ... Cell reports 11 (3), 390-404, 2015 | 232 | 2015 |
Breastmilk is a novel source of stem cells with multilineage differentiation potential F Hassiotou, A Beltran, E Chetwynd, AM Stuebe, AJ Twigger, P Metzger, ... Stem cells 30 (10), 2164-2174, 2012 | 223 | 2012 |
Targeted silencing of the oncogenic transcription factor SOX2 in breast cancer S Stolzenburg, MG Rots, AS Beltran, AG Rivenbark, X Yuan, H Qian, ... Nucleic acids research 40 (14), 6725-6740, 2012 | 149 | 2012 |
Generation of tumor-initiating cells by exogenous delivery of OCT4 transcription factor AS Beltran, AG Rivenbark, BT Richardson, X Yuan, H Quian, JP Hunt, ... Breast cancer research 13 (5), 1-21, 2011 | 99 | 2011 |
Re-activation of a dormant tumor suppressor gene maspin by designed transcription factors A Beltran, S Parikh, Y Liu, BD Cuevas, GL Johnson, BW Futscher, ... Oncogene 26 (19), 2791-2798, 2007 | 99 | 2007 |
Tumor-infiltrating regulatory T cells inhibit endogenous cytotoxic T cell responses to lung adenocarcinoma AP Ganesan, M Johansson, B Ruffell, A Beltran, J Lau, DM Jablons, ... The Journal of Immunology 191 (4), 2009-2017, 2013 | 98 | 2013 |
Enhancer remodeling during adaptive bypass to MEK inhibition is attenuated by pharmacologic targeting of the P-TEFb complex JS Zawistowski, SM Bevill, DR Goulet, TJ Stuhlmiller, AS Beltran, ... Cancer discovery 7 (3), 302-321, 2017 | 73 | 2017 |
Reprogramming epigenetic silencing: artificial transcription factors synergize with chromatin remodeling drugs to reactivate the tumor suppressor mammary serine protease inhibitor AS Beltran, X Sun, PM Lizardi, P Blancafort Molecular cancer therapeutics 7 (5), 1080-1090, 2008 | 62 | 2008 |
Stable oncogenic silencing in vivo by programmable and targeted de novo DNA methylation in breast cancer S Stolzenburg, AS Beltran, T Swift-Scanlan, AG Rivenbark, R Rashwan, ... Oncogene 34 (43), 5427-5435, 2015 | 60 | 2015 |
Novel role of Engrailed 1 as a prosurvival transcription factor in basal-like breast cancer and engineering of interference peptides block its oncogenic function AS Beltran, LM Graves, P Blancafort Oncogene 33 (39), 4767-4777, 2014 | 57 | 2014 |
Suppression of breast tumor growth and metastasis by an engineered transcription factor AS Beltran, A Russo, H Lara, C Fan, PM Lizardi, P Blancafort PloS one 6 (9), e24595, 2011 | 51 | 2011 |
EMX2 is epigenetically silenced and suppresses growth in human lung cancer J Okamoto, T Hirata, Z Chen, HM Zhou, I Mikami, H Li, A Beltran, ... Oncogene 29 (44), 5969-5975, 2010 | 46 | 2010 |
Targeting serous epithelial ovarian cancer with designer zinc finger transcription factors H Lara, Y Wang, AS Beltran, K Juárez-Moreno, X Yuan, S Kato, ... Journal of Biological Chemistry 287 (35), 29873-29886, 2012 | 43 | 2012 |
Reactivation of MASPIN in non-small cell lung carcinoma (NSCLC) cells by artificial transcription factors (ATFs) AS Beltran, P Blancafort Epigenetics 6 (2), 224-235, 2011 | 43 | 2011 |
Expression of the pluripotency transcription factor OCT4 in the normal and aberrant mammary gland F Hassiotou, A Hepworth, A Beltran, M Mathews, A Stuebe, P Hartmann, ... Frontiers in oncology 3, 79, 2013 | 38 | 2013 |
Interrogating genomes with combinatorial artificial transcription factor libraries: asking zinc finger questions A Beltran, Y Liu, S Parikh, B Temple, P Blancafort Assay and drug development technologies 4 (3), 317-331, 2006 | 33 | 2006 |
Understanding the X chromosome inactivation cycle in mice: a comprehensive view provided by nuclear transfer M Oikawa, K Inoue, H Shiura, S Matoba, S Kamimura, M Hirose, ... Epigenetics 9 (2), 204-211, 2014 | 27 | 2014 |
Breaking through an epigenetic wall: re-activation of Oct4 by KRAB-containing designer zinc finger transcription factors K Juárez-Moreno, R Erices, AS Beltran, S Stolzenburg, M Cuello-Fredes, ... Epigenetics 8 (2), 164-176, 2013 | 23 | 2013 |
Inheritance of OCT 4 predetermines fate choice in human embryonic stem cells SC Wolff, KM Kedziora, R Dumitru, CD Dungee, TM Zikry, AS Beltran, ... Molecular systems biology 14 (9), e8140, 2018 | 19 | 2018 |