FXR activation reverses insulin resistance and lipid abnormalities and protects against liver steatosis in Zucker (fa/fa) obese rats [S] S Cipriani, A Mencarelli, G Palladino, S Fiorucci Journal of lipid research 51 (4), 771-784, 2010 | 447 | 2010 |
Bile-acid-activated receptors: targeting TGR5 and farnesoid-X-receptor in lipid and glucose disorders S Fiorucci, A Mencarelli, G Palladino, S Cipriani Trends in pharmacological sciences 30 (11), 570-580, 2009 | 362 | 2009 |
Inhibition of NF-κB by a PXR-dependent pathway mediates counter-regulatory activities of rifaximin on innate immunity in intestinal epithelial cells A Mencarelli, B Renga, G Palladino, P Ricci, E Distrutti, M Barbanti, ... European journal of pharmacology 668 (1-2), 317-324, 2011 | 130 | 2011 |
Serum resistin, cardiovascular disease and all-cause mortality in patients with type 2 diabetes C Menzaghi, S Bacci, L Salvemini, C Mendonca, G Palladino, A Fontana, ... PLoS One 8 (6), e64729, 2013 | 125 | 2013 |
Applications and analysis of targeted genomic sequencing in cancer studies F Bewicke-Copley, EA Kumar, G Palladino, K Korfi, J Wang Computational and structural biotechnology journal 17, 1348-1359, 2019 | 116 | 2019 |
Pregnane-X-receptor mediates the anti-inflammatory activities of rifaximin on detoxification pathways in intestinal epithelial cells A Mencarelli, M Migliorati, M Barbanti, S Cipriani, G Palladino, E Distrutti, ... Biochemical pharmacology 80 (11), 1700-1707, 2010 | 115 | 2010 |
Probiotics modulate intestinal expression of nuclear receptor and provide counter-regulatory signals to inflammation-driven adipose tissue activation A Mencarelli, E Distrutti, B Renga, C D'Amore, S Cipriani, G Palladino, ... PLoS One 6 (7), e22978, 2011 | 104 | 2011 |
The plant sterol guggulsterone attenuates inflammation and immune dysfunction in murine models of inflammatory bowel disease A Mencarelli, B Renga, G Palladino, E Distrutti, S Fiorucci Biochemical pharmacology 78 (9), 1214-1223, 2009 | 103 | 2009 |
Development of non-antibiotic macrolide that corrects inflammation-driven immune dysfunction in models of inflammatory bowel diseases and arthritis A Mencarelli, E Distrutti, B Renga, S Cipriani, G Palladino, C Booth, ... European journal of pharmacology 665 (1-3), 29-39, 2011 | 77 | 2011 |
Targeting farnesoid-X-receptor: from medicinal chemistry to disease treatment S Fiorucci, A Mencarelli, E Distrutti, G Palladino, S Cipriani Current medicinal chemistry 17 (2), 139-159, 2010 | 74 | 2010 |
Specific covalent inhibition of MALT1 paracaspase suppresses B cell lymphoma growth L Fontán, Q Qiao, JM Hatcher, G Casalena, I Us, M Teater, M Durant, ... The Journal of clinical investigation 128 (10), 4397-4412, 2018 | 58 | 2018 |
Circulating adiponectin and cardiovascular mortality in patients with type 2 diabetes mellitus: evidence of sexual dimorphism C Menzaghi, M Xu, L Salvemini, C De Bonis, G Palladino, T Huang, ... Cardiovascular diabetology 13 (1), 1-8, 2014 | 48 | 2014 |
TRAP1 is involved in BRAF regulation and downstream attenuation of ERK phosphorylation and cell-cycle progression: a novel target for BRAF-mutated colorectal tumors V Condelli, A Piscazzi, L Sisinni, DS Matassa, F Maddalena, G Lettini, ... Cancer research 74 (22), 6693-6704, 2014 | 42 | 2014 |
Activation of the farnesoid‐X receptor protects against gastrointestinal injury caused by non‐steroidal anti‐inflammatory drugs in mice S Fiorucci, A Mencarelli, S Cipriani, B Renga, G Palladino, L Santucci, ... British journal of pharmacology 164 (8), 1929-1938, 2011 | 40 | 2011 |
The bile acid sensor FXR protects against dyslipidemia and aortic plaques development induced by the HIV protease inhibitor ritonavir in mice A Mencarelli, S Cipriani, B Renga, D Francisci, G Palladino, E Distrutti, ... PLoS One 5 (10), e13238, 2010 | 38 | 2010 |
Mechanistic role of p38 MAPK in gastric cancer dissemination in a rodent model peritoneal metastasis L Graziosi, A Mencarelli, C Santorelli, B Renga, S Cipriani, E Cavazzoni, ... European journal of pharmacology 674 (2-3), 143-152, 2012 | 36 | 2012 |
TRAP1 regulates cell cycle and apoptosis in thyroid carcinoma cells G Palladino, T Notarangelo, G Pannone, A Piscazzi, O Lamacchia, ... Endocrine-related cancer 23 (9), 699-709, 2016 | 34 | 2016 |
Targeting TRAP1 as a downstream effector of BRAF cytoprotective pathway: a novel strategy for human BRAF-driven colorectal carcinoma V Condelli, F Maddalena, L Sisinni, G Lettini, DS Matassa, A Piscazzi, ... Oncotarget 6 (26), 22298, 2015 | 34 | 2015 |
FXR activation improves myocardial fatty acid metabolism in a rodent model of obesity-driven cardiotoxicity A Mencarelli, S Cipriani, B Renga, C D’amore, G Palladino, E Distrutti, ... Nutrition, Metabolism and Cardiovascular Diseases 23 (2), 94-101, 2013 | 34 | 2013 |
Follicular lymphoma genomics L Pickard, G Palladino, J Okosun Leukemia & Lymphoma 61 (10), 2313-2323, 2020 | 13 | 2020 |