Interpreting the language of histone and DNA modifications SB Rothbart, BD Strahl Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839 (8), 627-643, 2014 | 545 | 2014 |
Association of UHRF1 with methylated H3K9 directs the maintenance of DNA methylation SB Rothbart, K Krajewski, N Nady, W Tempel, S Xue, AI Badeaux, ... Nature structural & molecular biology 19 (11), 1155, 2012 | 269 | 2012 |
An H3K36 methylation-engaging Tudor motif of polycomb-like proteins mediates PRC2 complex targeting L Cai, SB Rothbart, R Lu, B Xu, WY Chen, A Tripathy, S Rockowitz, ... Molecular cell 49 (3), 571-582, 2013 | 175 | 2013 |
Therapeutics by cytotoxic metabolite accumulation: pemetrexed causes ZMP accumulation, AMPK activation, and mammalian target of rapamycin inhibition AC Racanelli, SB Rothbart, CL Heyer, RG Moran Cancer research 69 (13), 5467-5474, 2009 | 150 | 2009 |
Multivalent histone engagement by the linked tandem Tudor and PHD domains of UHRF1 is required for the epigenetic inheritance of DNA methylation SB Rothbart, BM Dickson, MS Ong, K Krajewski, S Houliston, DB Kireev, ... Genes & development 27 (11), 1288-1298, 2013 | 137 | 2013 |
A histone methylation network regulates transgenerational epigenetic memory in C. elegans EL Greer, SE Beese-Sims, E Brookes, R Spadafora, Y Zhu, SB Rothbart, ... Cell reports 7 (1), 113-126, 2014 | 125 | 2014 |
The histone-H3K4-specific demethylase KDM5B binds to its substrate and product through distinct PHD fingers BJ Klein, L Piao, Y Xi, H Rincon-Arano, SB Rothbart, D Peng, H Wen, ... Cell reports 6 (2), 325-335, 2014 | 114 | 2014 |
An interactive database for the assessment of histone antibody specificity SB Rothbart, BM Dickson, JR Raab, AT Grzybowski, K Krajewski, AH Guo, ... Molecular cell 59 (3), 502-511, 2015 | 108 | 2015 |
Pemetrexed indirectly activates the metabolic kinase AMPK in human carcinomas SB Rothbart, AC Racanelli, RG Moran Cancer research 70 (24), 10299-10309, 2010 | 92 | 2010 |
Neuronal stress pathway mediating a histone methyl/phospho switch is required for herpes simplex virus reactivation AR Cliffe, JH Arbuckle, JL Vogel, MJ Geden, SB Rothbart, CL Cusack, ... Cell host & microbe 18 (6), 649-658, 2015 | 89 | 2015 |
Structural basis for DNMT3A-mediated de novo DNA methylation ZM Zhang, R Lu, P Wang, Y Yu, D Chen, L Gao, S Liu, D Ji, SB Rothbart, ... Nature 554 (7692), 387-391, 2018 | 82 | 2018 |
Hemi-methylated DNA regulates DNA methylation inheritance through allosteric activation of H3 ubiquitylation by UHRF1 JS Harrison, EM Cornett, D Goldfarb, PA DaRosa, ZM Li, F Yan, ... elife 5, e17101, 2016 | 72 | 2016 |
Tandem PHD fingers of MORF/MOZ acetyltransferases display selectivity for acetylated histone H3 and are required for the association with chromatin M Ali, K Yan, ME Lalonde, C Degerny, SB Rothbart, BD Strahl, J Côté, ... Journal of molecular biology 424 (5), 328-338, 2012 | 72 | 2012 |
A DNA methylation reader complex that enhances gene transcription CJ Harris, M Scheibe, SP Wongpalee, W Liu, EM Cornett, RM Vaughan, ... Science 362 (6419), 1182-1186, 2018 | 67 | 2018 |
An allosteric interaction links USP7 to deubiquitination and chromatin targeting of UHRF1 ZM Zhang, SB Rothbart, DF Allison, Q Cai, JS Harrison, L Li, Y Wang, ... Cell reports 12 (9), 1400-1406, 2015 | 67 | 2015 |
Molecular basis for chromatin binding and regulation of MLL5 M Ali, H Rincón-Arano, W Zhao, SB Rothbart, Q Tong, SM Parkhurst, ... Proceedings of the National Academy of Sciences 110 (28), 11296-11301, 2013 | 66 | 2013 |
Peptide microarrays to interrogate the “histone code” SB Rothbart, K Krajewski, BD Strahl, SM Fuchs Methods in enzymology 512, 107-135, 2012 | 64 | 2012 |
AMP-activated protein kinase (AMPK) control of mTORC1 is p53-and TSC2-independent in pemetrexed-treated carcinoma cells S Agarwal, CM Bell, SB Rothbart, RG Moran Journal of Biological Chemistry 290 (46), 27473-27486, 2015 | 44 | 2015 |
A D53 repression motif induces oligomerization of TOPLESS corepressors and promotes assembly of a corepressor-nucleosome complex H Ma, J Duan, J Ke, Y He, X Gu, TH Xu, H Yu, Y Wang, JS Brunzelle, ... Science advances 3 (6), e1601217, 2017 | 40 | 2017 |
Dido3 PHD modulates cell differentiation and division J Gatchalian, A Fütterer, SB Rothbart, Q Tong, H Rincon-Arano, ... Cell reports 4 (1), 148-158, 2013 | 40 | 2013 |