| Extending healthy life span—from yeast to humans L Fontana, L Partridge, VD Longo science 328 (5976), 321-326, 2010 | 2512 | 2010 |
| Diet drives convergence in gut microbiome functions across mammalian phylogeny and within humans BD Muegge, J Kuczynski, D Knights, JC Clemente, A González, ... Science 332 (6032), 970-974, 2011 | 1459 | 2011 |
| Visceral fat adipokine secretion is associated with systemic inflammation in obese humans L Fontana, JC Eagon, ME Trujillo, PE Scherer, S Klein Diabetes 56 (4), 1010-1013, 2007 | 1299 | 2007 |
| Absence of an effect of liposuction on insulin action and risk factors for coronary heart disease S Klein, L Fontana, VL Young, AR Coggan, C Kilo, BW Patterson, ... New England Journal of Medicine 350 (25), 2549-2557, 2004 | 1010 | 2004 |
| Long-term calorie restriction is highly effective in reducing the risk for atherosclerosis in humans L Fontana, TE Meyer, S Klein, JO Holloszy Proceedings of the national Academy of Sciences 101 (17), 6659-6663, 2004 | 975 | 2004 |
| Promoting Health and Longevity through Diet: from Model Organisms to Humans L Partridge, L Fontana Cell, 2015 | 795* | 2015 |
| Low protein intake is associated with a major reduction in IGF-1, cancer, and overall mortality in the 65 and younger but not older population ME Levine, JA Suarez, S Brandhorst, P Balasubramanian, CW Cheng, ... Cell metabolism 19 (3), 407-417, 2014 | 668 | 2014 |
| Aging, adiposity, and calorie restriction L Fontana, S Klein Jama 297 (9), 986-994, 2007 | 592 | 2007 |
| Interventions to slow aging in humans: are we ready? VD Longo, A Antebi, A Bartke, N Barzilai, HM Brown‐Borg, C Caruso, ... Aging cell 14 (4), 497-510, 2015 | 431 | 2015 |
| Caloric restriction in humans JO Holloszy, L Fontana Experimental gerontology 42 (8), 709-712, 2007 | 417 | 2007 |
| Long‐term effects of calorie or protein restriction on serum IGF‐1 and IGFBP‐3 concentration in humans L Fontana, EP Weiss, DT Villareal, S Klein, JO Holloszy Aging cell 7 (5), 681-687, 2008 | 408 | 2008 |
| Meal frequency and timing in health and disease MP Mattson, DB Allison, L Fontana, M Harvie, VD Longo, WJ Malaisse, ... Proceedings of the National Academy of Sciences 111 (47), 16647-16653, 2014 | 400 | 2014 |
| Long-term caloric restriction ameliorates the decline in diastolic function in humans TE Meyer, SJ Kovács, AA Ehsani, S Klein, JO Holloszy, L Fontana Journal of the American College of Cardiology 47 (2), 398-402, 2006 | 400 | 2006 |
| Improvements in glucose tolerance and insulin action induced by increasing energy expenditure or decreasing energy intake: a randomized controlled trial Washington University School of Medicine CALERIE Group Weiss Edward P ... The American journal of clinical nutrition 84 (5), 1033-1042, 2006 | 389 | 2006 |
| Fasting and cancer treatment in humans: A case series report FM Safdie, T Dorff, D Quinn, L Fontana, M Wei, C Lee, P Cohen, ... Aging (Albany NY) 1 (12), 988, 2009 | 372 | 2009 |
| Calorie restriction and cancer prevention: metabolic and molecular mechanisms VD Longo, L Fontana Trends in pharmacological sciences 31 (2), 89-98, 2010 | 363 | 2010 |
| Resveratrol supplementation does not improve metabolic function in nonobese women with normal glucose tolerance J Yoshino, C Conte, L Fontana, B Mittendorfer, S Imai, KB Schechtman, ... Cell metabolism 16 (5), 658-664, 2012 | 359 | 2012 |
| Bone mineral density response to caloric restriction–induced weight loss or exercise-induced weight loss: a randomized controlled trial DT Villareal, L Fontana, EP Weiss, SB Racette, K Steger-May, ... Archives of internal medicine 166 (22), 2502-2510, 2006 | 336 | 2006 |
| Effect of lifestyle intervention on metabolic coronary heart disease risk factors in obese older adults DT Villareal, BV Miller III, M Banks, L Fontana, DR Sinacore, S Klein The American journal of clinical nutrition 84 (6), 1317-1323, 2006 | 306 | 2006 |
| A 2-year randomized controlled trial of human caloric restriction: feasibility and effects on predictors of health span and longevity E Ravussin, LM Redman, J Rochon, SK Das, L Fontana, WE Kraus, ... The Journals of Gerontology: Series A 70 (9), 1097-1104, 2015 | 305 | 2015 |
Klein SamuelVerified email at dom.wustl.edu
