|Relaxin family peptides and their receptors|
RAD Bathgate, ML Halls, ET van der Westhuizen, GE Callander, M Kocan, ...
Physiological reviews 93 (1), 405-480, 2013
|Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4|
P Zhao, TM Lieu, N Barlow, M Metcalf, NA Veldhuis, DD Jensen, M Kocan, ...
Journal of Biological Chemistry 289 (39), 27215-27234, 2014
|Demonstration of improvements to the bioluminescence resonance energy transfer (BRET) technology for the monitoring of G protein–coupled receptors in live cells|
M Kocan, HB See, RM Seeber, KA Eidne, KDG Pfleger
Journal of biomolecular screening 13 (9), 888-898, 2008
|Two-Component Systems of Corynebacterium glutamicum: Deletion Analysis and Involvement of the PhoS-PhoR System in the Phosphate Starvation Response|
M Kocan, S Schaffer, T Ishige, U Sorger-Herrmann, VF Wendisch, M Bott
Journal of bacteriology 188 (2), 724-732, 2006
|Relaxin requires the angiotensin II type 2 receptor to abrogate renal interstitial fibrosis|
BSM Chow, M Kocan, S Bosnyak, M Sarwar, B Wigg, ES Jones, ...
Kidney international 86 (1), 75-85, 2014
|Minimization of human relaxin-3 leading to high-affinity analogues with increased selectivity for relaxin-family peptide 3 receptor (RXFP3) over RXFP1|
F Shabanpoor, M Akhter Hossain, PJ Ryan, A Belgi, S Layfield, M Kocan, ...
Journal of medicinal chemistry 55 (4), 1671-1681, 2012
|The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts|
DD Jensen, CB Godfrey, C Niklas, M Canals, M Kocan, DP Poole, ...
Journal of Biological Chemistry 288 (32), 22942-22960, 2013
|A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1|
MA Hossain, M Kocan, ST Yao, SG Royce, VB Nair, C Siwek, NA Patil, ...
Chemical science 7 (6), 3805-3819, 2016
|Application of G Protein-Coupled Receptor-Heteromer Identification Technology to Monitor β-Arrestin Recruitment to G Protein-Coupled Receptor Heteromers|
HB See, RM Seeber, M Kocan, KA Eidne, KDG Pfleger
Assay and drug development technologies 9 (1), 21-30, 2011
|Agonist-independent interactions between β-arrestins and mutant vasopressin type II receptors associated with nephrogenic syndrome of inappropriate antidiuresis|
M Kocan, HB See, NG Sampaio, KA Eidne, BJ Feldman, KDG Pfleger
Molecular endocrinology 23 (4), 559-571, 2009
|Enhanced BRET technology for the monitoring of agonist-induced and agonist-independent interactions between GPCRs and β-arrestins|
M Kocan, M Dalrymple, R Seeber, B Feldman, K Pfleger
Frontiers in Endocrinology 1, 12, 2011
|Study of GPCR–protein interactions by BRET|
M Kocan, KDG Pfleger
Receptor Signal Transduction Protocols, 357-371, 2011
|The anti-fibrotic actions of relaxin are mediated through a NO-sGC-cGMP-dependent pathway in renal myofibroblasts in vitro and enhanced by the NO donor, diethylamine NONOate|
C Wang, BK Kemp-Harper, M Kocan, SY Ang, TD Hewitson, CS Samuel
Frontiers in pharmacology 7, 91, 2016
|Biocompatibility of semiconducting AlGaN/GaN material with living cells|
A Podolska, S Tham, RD Hart, RM Seeber, M Kocan, M Kocan, UK Mishra, ...
Sensors and Actuators B: Chemical 169, 401-406, 2012
|β2‐Adrenoceptors increase translocation of GLUT4 via GPCR kinase sites in the receptor C‐terminal tail|
N Dehvari, DS Hutchinson, J Nevzorova, OS Dallner, M Sato, M Kocan, ...
British journal of pharmacology 165 (5), 1442-1456, 2012
|ML290 is a biased allosteric agonist at the relaxin receptor RXFP1|
M Kocan, M Sarwar, SY Ang, J Xiao, JJ Marugan, MA Hossain, C Wang, ...
Scientific reports 7 (1), 1-14, 2017
|Minimum active structure of insulin-like peptide 5|
A Belgi, RAD Bathgate, M Kocan, N Patil, S Zhang, GW Tregear, JD Wade, ...
Journal of medicinal chemistry 56 (23), 9509-9516, 2013
|The relaxin receptor as a therapeutic target–perspectives from evolution and drug targeting|
RAD Bathgate, M Kocan, DJ Scott, MA Hossain, SV Good, S Yegorov, ...
Pharmacology & therapeutics 187, 114-132, 2018
|Detection of GPCR/β-arrestin interactions in live cells using bioluminescence resonance energy transfer technology|
M Kocan, KDG Pfleger
G Protein-Coupled Receptors in Drug Discovery, 305-317, 2009
|Signalling profiles of H 3 relaxin, H 2 relaxin and R 3 (BΔ 23–27) R/I 5 acting at the relaxin family peptide receptor 3 (RXFP 3)|
M Kocan, M Sarwar, MA Hossain, JD Wade, RJ Summers
British journal of pharmacology 171 (11), 2827-2841, 2014