Relaxin family peptides and their receptors RAD Bathgate, ML Halls, ET van der Westhuizen, GE Callander, M Kocan, ... Physiological reviews 93 (1), 405-480, 2013 | 540 | 2013 |
Cathepsin S causes inflammatory pain via biased agonism of PAR2 and TRPV4 P Zhao, TM Lieu, N Barlow, M Metcalf, NA Veldhuis, DD Jensen, M Kocan, ... Journal of Biological Chemistry 289 (39), 27215-27234, 2014 | 183 | 2014 |
Relaxin requires the angiotensin II type 2 receptor to abrogate renal interstitial fibrosis BSM Chow, M Kocan, S Bosnyak, M Sarwar, B Wigg, ES Jones, ... Kidney international 86 (1), 75-85, 2014 | 123 | 2014 |
Demonstration of improvements to the bioluminescence resonance energy transfer (BRET) technology for the monitoring of G protein–coupled receptors in live cells M Kocan, HB See, RM Seeber, KA Eidne, KDG Pfleger SLAS Discovery 13 (9), 888-898, 2008 | 114 | 2008 |
Two-Component Systems of Corynebacterium glutamicum: Deletion Analysis and Involvement of the PhoS-PhoR System in the Phosphate Starvation Response M Kocan, S Schaffer, T Ishige, U Sorger-Herrmann, VF Wendisch, M Bott Journal of bacteriology 188 (2), 724-732, 2006 | 110 | 2006 |
Minimization of human relaxin-3 leading to high-affinity analogues with increased selectivity for relaxin-family peptide 3 receptor (RXFP3) over RXFP1 F Shabanpoor, M Akhter Hossain, PJ Ryan, A Belgi, S Layfield, M Kocan, ... Journal of medicinal chemistry 55 (4), 1671-1681, 2012 | 93 | 2012 |
A single-chain derivative of the relaxin hormone is a functionally selective agonist of the G protein-coupled receptor, RXFP1 MA Hossain, M Kocan, ST Yao, SG Royce, VB Nair, C Siwek, NA Patil, ... Chemical science 7 (6), 3805-3819, 2016 | 91 | 2016 |
The bile acid receptor TGR5 does not interact with β-arrestins or traffic to endosomes but transmits sustained signals from plasma membrane rafts DD Jensen, CB Godfrey, C Niklas, M Canals, M Kocan, DP Poole, ... Journal of Biological Chemistry 288 (32), 22942-22960, 2013 | 87 | 2013 |
ML290 is a biased allosteric agonist at the relaxin receptor RXFP1 M Kocan, M Sarwar, SY Ang, J Xiao, JJ Marugan, MA Hossain, C Wang, ... Scientific reports 7 (1), 2968, 2017 | 56 | 2017 |
Application of G Protein-Coupled Receptor-Heteromer Identification Technology to Monitor β-Arrestin Recruitment to G Protein-Coupled Receptor Heteromers HB See, RM Seeber, M Kocan, KA Eidne, KDG Pfleger Assay and drug development technologies 9 (1), 21-30, 2011 | 53 | 2011 |
Agonist-independent interactions between β-arrestins and mutant vasopressin type II receptors associated with nephrogenic syndrome of inappropriate antidiuresis M Kocan, HB See, NG Sampaio, KA Eidne, BJ Feldman, KDG Pfleger Molecular endocrinology 23 (4), 559-571, 2009 | 49 | 2009 |
The Anti-fibrotic Actions of Relaxin Are Mediated Through a NO-sGC-cGMP-Dependent Pathway in Renal Myofibroblasts In Vitro and Enhanced by the NO Donor … C Wang, BK Kemp-Harper, M Kocan, SY Ang, TD Hewitson, CS Samuel Frontiers in pharmacology 7, 91, 2016 | 46 | 2016 |
Biocompatibility of semiconducting AlGaN/GaN material with living cells A Podolska, S Tham, RD Hart, RM Seeber, M Kocan, M Kocan, UK Mishra, ... Sensors and Actuators B: Chemical 169, 401-406, 2012 | 41 | 2012 |
Enhanced BRET technology for the monitoring of agonist-induced and agonist-independent interactions between GPCRs and β-arrestins M Kocan, MB Dalrymple, RM Seeber, BJ Feldman, KDG Pfleger Frontiers in Endocrinology 1, 12, 2011 | 41 | 2011 |
AT1R-AT2R-RXFP1 functional crosstalk in myofibroblasts: impact on the therapeutic targeting of renal and cardiac fibrosis BSM Chow, M Kocan, M Shen, Y Wang, L Han, JY Chew, C Wang, ... Journal of the American Society of Nephrology 30 (11), 2191-2207, 2019 | 40 | 2019 |
Understanding relaxin signalling at the cellular level AL Valkovic, RAD Bathgate, CS Samuel, M Kocan Molecular and cellular endocrinology 487, 24-33, 2019 | 39 | 2019 |
β2‐Adrenoceptors increase translocation of GLUT4 via GPCR kinase sites in the receptor C‐terminal tail N Dehvari, DS Hutchinson, J Nevzorova, OS Dallner, M Sato, M Kocan, ... British journal of pharmacology 165 (5), 1442-1456, 2012 | 38 | 2012 |
An apically located hybrid guanylate cyclase–ATPase is critical for the initiation of Ca2+ signaling and motility in Toxoplasma gondii L Yang, AD Uboldi, S Seizova, ML Wilde, MJ Coffey, NJ Katris, ... Journal of Biological Chemistry 294 (22), 8959-8972, 2019 | 37 | 2019 |
Study of GPCR–protein interactions by BRET M Kocan, KDG Pfleger Receptor Signal Transduction Protocols: Third Edition, 357-371, 2011 | 37 | 2011 |
The relaxin receptor as a therapeutic target–perspectives from evolution and drug targeting RAD Bathgate, M Kocan, DJ Scott, MA Hossain, SV Good, S Yegorov, ... Pharmacology & therapeutics 187, 114-132, 2018 | 34 | 2018 |