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Hayk Davtyan
Hayk Davtyan
Associate Research Professor
Verified email at uci.edu
Title
Cited by
Cited by
Year
A transgenic Alzheimer rat with plaques, tau pathology, behavioral impairment, oligomeric aβ, and frank neuronal loss
RM Cohen, K Rezai-Zadeh, TM Weitz, A Rentsendorj, D Gate, I Spivak, ...
Journal of Neuroscience 33 (15), 6245-6256, 2013
5272013
The adaptive immune system restrains Alzheimer’s disease pathogenesis by modulating microglial function
SE Marsh, EM Abud, A Lakatos, A Karimzadeh, ST Yeung, H Davtyan, ...
Proceedings of the National Academy of Sciences 113 (9), E1316-E1325, 2016
3652016
Development and validation of a simplified method to generate human microglia from pluripotent stem cells
A McQuade, M Coburn, CH Tu, J Hasselmann, H Davtyan, ...
Molecular neurodegeneration 13, 1-13, 2018
2812018
Development of a chimeric model to study and manipulate human microglia in vivo
J Hasselmann, MA Coburn, W England, DXF Velez, SK Shabestari, ...
Neuron 103 (6), 1016-1033. e10, 2019
2462019
Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations
R Rojo, A Raper, DD Ozdemir, L Lefevre, K Grabert, ...
Nature communications 10 (1), 3215, 2019
2242019
Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer’s disease
A McQuade, YJ Kang, J Hasselmann, A Jairaman, A Sotelo, M Coburn, ...
Nature communications 11 (1), 5370, 2020
1972020
Immunogenicity, efficacy, safety, and mechanism of action of epitope vaccine (Lu AF20513) for Alzheimer's disease: prelude to a clinical trial
H Davtyan, A Ghochikyan, I Petrushina, A Hovakimyan, A Davtyan, ...
Journal of Neuroscience 33 (11), 4923-4934, 2013
1822013
The binding of ethidium bromide with DNA: interaction with single-and double-stranded structures
PO Vardevanyan, AP Antonyan, MA Parsadanyan, HG Davtyan, ...
Experimental & Molecular Medicine 35 (6), 527-533, 2003
1662003
Reducing AD-like pathology in 3xTg-AD mouse model by DNA epitope vaccine—a novel immunotherapeutic strategy
N Movsesyan, A Ghochikyan, M Mkrtichyan, I Petrushina, H Davtyan, ...
PloS one 3 (5), e2124, 2008
1392008
Alzheimer's disease peptide epitope vaccine reduces insoluble but not soluble/oligomeric Aβ species in amyloid precursor protein transgenic mice
I Petrushina, A Ghochikyan, M Mktrichyan, G Mamikonyan, N Movsesyan, ...
Journal of Neuroscience 27 (46), 12721-12731, 2007
1282007
Modeling sporadic Alzheimer's disease in human brain organoids under serum exposure
X Chen, G Sun, E Tian, M Zhang, H Davtyan, TG Beach, EM Reiman, ...
Advanced Science 8 (18), 2101462, 2021
892021
Induction of mesoderm and neural crest-derived pericytes from human pluripotent stem cells to study blood-brain barrier interactions
T Faal, DTT Phan, H Davtyan, VM Scarfone, E Varady, M Blurton-Jones, ...
Stem Cell Reports 12 (3), 451-460, 2019
882019
C9orf72 deficiency promotes microglial-mediated synaptic loss in aging and amyloid accumulation
D Lall, I Lorenzini, TA Mota, S Bell, TE Mahan, JD Ulrich, H Davtyan, ...
Neuron 109 (14), 2275-2291. e8, 2021
862021
Plaque-associated human microglia accumulate lipid droplets in a chimeric model of Alzheimer’s disease
C Claes, EP Danhash, J Hasselmann, JP Chadarevian, SK Shabestari, ...
Molecular neurodegeneration 16, 1-11, 2021
732021
DNA prime–protein boost increased the titer, avidity and persistence of anti-Aβ antibodies in wild-type mice
H Davtyan, M Mkrtichyan, N Movsesyan, I Petrushina, G Mamikonyan, ...
Gene therapy 17 (2), 261-271, 2010
612010
Differential pulse voltammetric studies of ethidium bromide binding to DNA
SH Minasyan, LA Tavadyan, AP Antonyan, HG Davtyan, MA Parsadanyan, ...
Bioelectrochemistry 68 (1), 48-55, 2006
612006
Absence of microglia promotes diverse pathologies and early lethality in Alzheimer’s disease mice
SK Shabestari, S Morabito, EP Danhash, A McQuade, JR Sanchez, ...
Cell reports 39 (11), 2022
582022
Humanized monoclonal antibody armanezumab specific to N-terminus of pathological tau: characterization and therapeutic potency
MG Agadjanyan, K Zagorski, I Petrushina, H Davtyan, K Kazarian, ...
Molecular neurodegeneration 12, 1-18, 2017
562017
Targeting TLR-4 with a novel pharmaceutical grade plant derived agonist, Immunomax®, as a therapeutic strategy for metastatic breast cancer
A Ghochikyan, A Pichugin, A Bagaev, A Davtyan, A Hovakimyan, ...
Journal of Translational Medicine 12, 1-12, 2014
552014
Immunogenicity of epitope vaccines targeting different B cell antigenic determinants of human α-synuclein: Feasibility study
A Ghochikyan, I Petrushina, H Davtyan, A Hovakimyan, T Saing, ...
Neuroscience letters 560, 86-91, 2014
552014
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