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Joshua Gould
Joshua Gould
Broad Institute
Email verificata su broadinstitute.org
Titolo
Citata da
Citata da
Anno
A next generation connectivity map: L1000 platform and the first 1,000,000 profiles
A Subramanian, R Narayan, SM Corsello, DD Peck, TE Natoli, X Lu, ...
Cell 171 (6), 1437-1452. e17, 2017
25342017
GenePattern 2.0
M Reich, T Liefeld, J Gould, J Lerner, P Tamayo, JP Mesirov
Nature genetics 38 (5), 500-501, 2006
22422006
Tumour micro-environment elicits innate resistance to RAF inhibitors through HGF secretion
R Straussman, T Morikawa, K Shee, M Barzily-Rokni, ZR Qian, J Du, ...
Nature 487 (7408), 500-504, 2012
19472012
GSEA-P: a desktop application for Gene Set Enrichment Analysis
A Subramanian, H Kuehn, J Gould, P Tamayo, JP Mesirov
Bioinformatics 23 (23), 3251-3253, 2007
13752007
Discovery and prioritization of somatic mutations in diffuse large B-cell lymphoma (DLBCL) by whole-exome sequencing
JG Lohr, P Stojanov, MS Lawrence, D Auclair, B Chapuy, C Sougnez, ...
Proceedings of the National Academy of Sciences 109 (10), 3879-3884, 2012
11292012
Widespread genetic heterogeneity in multiple myeloma: implications for targeted therapy
JG Lohr, P Stojanov, SL Carter, P Cruz-Gordillo, MS Lawrence, D Auclair, ...
Cancer cell 25 (1), 91-101, 2014
10952014
High-definition spatial transcriptomics for in situ tissue profiling
S Vickovic, G Eraslan, F Salmén, J Klughammer, L Stenbeck, D Schapiro, ...
Nature methods 16 (10), 987-990, 2019
8172019
The Drug Repurposing Hub: a next-generation drug library and information resource
SM Corsello, JA Bittker, Z Liu, J Gould, P McCarren, JE Hirschman, ...
Nature medicine 23 (4), 405-408, 2017
7992017
Optimal-transport analysis of single-cell gene expression identifies developmental trajectories in reprogramming
G Schiebinger, J Shu, M Tabaka, B Cleary, V Subramanian, A Solomon, ...
Cell 176 (4), 928-943. e22, 2019
6792019
Harnessing connectivity in a large-scale small-molecule sensitivity dataset
B Seashore-Ludlow, MG Rees, JH Cheah, M Cokol, EV Price, ME Coletti, ...
Cancer discovery 5 (11), 1210-1223, 2015
6502015
COVID-19 tissue atlases reveal SARS-CoV-2 pathology and cellular targets
TM Delorey, CGK Ziegler, G Heimberg, R Normand, Y Yang, ...
Nature 595 (7865), 107-113, 2021
5952021
Systematic investigation of genetic vulnerabilities across cancer cell lines reveals lineage-specific dependencies in ovarian cancer
HW Cheung, GS Cowley, BA Weir, JS Boehm, S Rusin, JA Scott, A East, ...
Proceedings of the National Academy of Sciences 108 (30), 12372-12377, 2011
5002011
A single-cell and single-nucleus RNA-Seq toolbox for fresh and frozen human tumors
M Slyper, CBM Porter, O Ashenberg, J Waldman, E Drokhlyansky, ...
Nature medicine 26 (5), 792-802, 2020
4342020
Single-cell meta-analysis of SARS-CoV-2 entry genes across tissues and demographics
C Muus, MD Luecken, G Eraslan, L Sikkema, A Waghray, G Heimberg, ...
Nature medicine 27 (3), 546-559, 2021
2962021
High-throughput identification of genotype-specific cancer vulnerabilities in mixtures of barcoded tumor cell lines
C Yu, AM Mannan, GM Yvone, KN Ross, YL Zhang, MA Marton, BR Taylor, ...
Nature biotechnology 34 (4), 419-423, 2016
2942016
Integrated analyses of single-cell atlases reveal age, gender, and smoking status associations with cell type-specific expression of mediators of SARS-CoV-2 viral entry and …
C Muus, MD Luecken, G Eraslan, A Waghray, G Heimberg, L Sikkema, ...
BioRxiv, 2020.04. 19.049254, 2020
2552020
Prognostic gene expression signature for patients with hepatitis C–related early-stage cirrhosis
Y Hoshida, A Villanueva, A Sangiovanni, M Sole, C Hur, KL Andersson, ...
Gastroenterology 144 (5), 1024-1030, 2013
2362013
Comparative gene marker selection suite
J Gould, G Getz, S Monti, M Reich, JP Mesirov
Bioinformatics 22 (15), 1924-1925, 2006
1442006
Genetic interrogation of circulating multiple myeloma cells at single-cell resolution
JG Lohr, S Kim, J Gould, B Knoechel, Y Drier, MJ Cotton, D Gray, N Birrer, ...
Science translational medicine 8 (363), 363ra147-363ra147, 2016
1422016
Targeting MTHFD2 in acute myeloid leukemia
Y Pikman, A Puissant, G Alexe, A Furman, LM Chen, SM Frumm, L Ross, ...
Journal of Experimental Medicine 213 (7), 1285-1306, 2016
1332016
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