| Altered insulin signaling in Alzheimer’s disease brain–special emphasis on PI3K-Akt pathway S Gabbouj, S Ryhänen, M Marttinen, R Wittrahm, M Takalo, ... Frontiers in neuroscience 13, 629, 2019 | 303 | 2019 |
| Synaptic dysfunction and septin protein family members in neurodegenerative diseases M Marttinen, KMA Kurkinen, H Soininen, A Haapasalo, M Hiltunen Molecular neurodegeneration 10, 1-12, 2015 | 122 | 2015 |
| Molecular mechanisms of synaptotoxicity and neuroinflammation in Alzheimer's disease M Marttinen, M Takalo, T Natunen, R Wittram, S Gabbouj, S Kemppainen, ... Frontiers in neuroscience 12, 963, 2018 | 78 | 2018 |
| The Alzheimer’s disease-associated protective Plcγ2-P522R variant promotes immune functions M Takalo, R Wittrahm, B Wefers, S Parhizkar, K Jokivarsi, T Kuulasmaa, ... Molecular Neurodegeneration 15, 1-14, 2020 | 67 | 2020 |
| BIN1 recovers tauopathy-induced long-term memory deficits in mice and interacts with Tau through Thr348 phosphorylation M Sartori, T Mendes, S Desai, A Lasorsa, A Herledan, N Malmanche, ... Acta neuropathologica 138, 631-652, 2019 | 60 | 2019 |
| A multiomic approach to characterize the temporal sequence in Alzheimer's disease-related pathology M Marttinen, J Paananen, A Neme, V Mitra, M Takalo, T Natunen, ... Neurobiology of disease 124, 454-468, 2019 | 44 | 2019 |
| DHCR24 exerts neuroprotection upon inflammation-induced neuronal death H Martiskainen, KMA Paldanius, T Natunen, M Takalo, M Marttinen, ... Journal of neuroinflammation 14, 1-16, 2017 | 42 | 2017 |
| Astrocytes and microglia as potential contributors to the pathogenesis of C9orf72 repeat expansion-associated FTLD and ALS H Rostalski, S Leskelä, N Huber, K Katisko, A Cajanus, E Solje, ... Frontiers in neuroscience 13, 457185, 2019 | 41 | 2019 |
| Relationship between ubiquilin-1 and BACE1 in human Alzheimer's disease and APdE9 transgenic mouse brain and cell-based models T Natunen, M Takalo, S Kemppainen, S Leskelä, M Marttinen, ... Neurobiology of disease 85, 187-205, 2016 | 36 | 2016 |
| Alzheimer’s genetic risk factor FERMT2 (Kindlin-2) controls axonal growth and synaptic plasticity in an APP-dependent manner F Eysert, A Coulon, E Boscher, AC Vreulx, A Flaig, T Mendes, S Hughes, ... Molecular psychiatry 26 (10), 5592-5607, 2021 | 32 | 2021 |
| Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice S Gabbouj, T Natunen, H Koivisto, K Jokivarsi, M Takalo, M Marttinen, ... Neurobiology of Aging 75, 98-108, 2019 | 32 | 2019 |
| Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques T Natunen, H Martiskainen, M Marttinen, S Gabbouj, H Koivisto, ... Molecular neurodegeneration 15, 1-30, 2020 | 23 | 2020 |
| SEPT8 modulates β-amyloidogenic processing of APP by affecting the sorting and accumulation of BACE1 KMA Kurkinen, M Marttinen, L Turner, T Natunen, P Mäkinen, ... Journal of Cell Science 129 (11), 2224-2238, 2016 | 22 | 2016 |
| Decreased plasma C‐reactive protein levels in APOE ε4 allele carriers H Martiskainen, M Takalo, A Solomon, A Stančáková, M Marttinen, ... Annals of Clinical and Translational Neurology 5 (10), 1229-1240, 2018 | 19 | 2018 |
| Genetic variation in δ-opioid receptor associates with increased β-and γ-secretase activity in the late stages of Alzheimer’s disease T Sarajärvi, M Marttinen, T Natunen, T Kauppinen, P Mäkinen, S Helisalmi, ... Journal of Alzheimer's Disease 48 (2), 507-516, 2015 | 16 | 2015 |
| Behavioral testing of mice exposed to intermediate frequency magnetic fields indicates mild memory impairment K Kumari, H Koivisto, M Viluksela, KMA Paldanius, M Marttinen, ... PloS one 12 (12), e0188880, 2017 | 11 | 2017 |
| MECP2 Increases the pro-inflammatory response of microglial cells and phosphorylation at serine 423 regulates neuronal gene expression upon neuroinflammation R Wittrahm, M Takalo, M Marttinen, T Kuulasmaa, P Mäkinen, ... Cells 10 (4), 860, 2021 | 9 | 2021 |
| Presynaptic vesicle protein SEPTIN5 regulates the degradation of APP C-terminal fragments and the levels of aβ M Marttinen, CB Ferreira, KMA Paldanius, M Takalo, T Natunen, ... Cells 9 (11), 2482, 2020 | 7 | 2020 |
| Supervised pathway analysis of blood gene expression profiles in Alzheimer's disease E Moradi, M Marttinen, T Häkkinen, M Hiltunen, M Nykter Neurobiology of aging 84, 98-108, 2019 | 7 | 2019 |
| S327 phosphorylation of the presynaptic protein SEPTIN5 increases in the early stages of neurofibrillary pathology and alters the functionality of SEPTIN5 CB Ferreira, M Marttinen, JE Coelho, KMA Paldanius, M Takalo, ... Neurobiology of Disease 163, 105603, 2022 | 4 | 2022 |
