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lu-yun lian
lu-yun lian
Professor of Structural Biology, University of Liverpool
Email verificata su liverpool.ac.uk
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A simple method for improving protein solubility and long-term stability
AP Golovanov, GM Hautbergue, SA Wilson, LY Lian
Journal of the American Chemical Society 126 (29), 8933-8939, 2004
5772004
Cytochrome P450 6M2 from the malaria vector Anopheles gambiae metabolizes pyrethroids: Sequential metabolism of deltamethrin revealed
BJ Stevenson, J Bibby, P Pignatelli, S Muangnoicharoen, PM O’Neill, ...
Insect biochemistry and molecular biology 41 (7), 492-502, 2011
2702011
A Model for Human Cytochrome P450 2D6 Based on Homology Modeling and NMR Studies of Substrate Binding
S Modi, MJ Paine, MJ Sutcliffe, LY Lian, WU Primrose, CR Wolf, ...
Biochemistry 35 (14), 4540-4550, 1996
2211996
Mutually exclusive interactions drive handover of mRNA from export adaptors to TAP
GM Hautbergue, ML Hung, AP Golovanov, LY Lian, SA Wilson
Proceedings of the National Academy of Sciences 105 (13), 5154-5159, 2008
2132008
A single mutation in cytochrome P450 BM3 changes substrate orientation in a catalytic intermediate and the regiospecificity of hydroxylation
CF Oliver, S Modi, MJ Sutcliffe, WU Primrose, LY Lian, GCK Roberts
Biochemistry 36 (7), 1567-1572, 1997
2041997
Molecular basis of RNA recognition and TAP binding by the SR proteins SRp20 and 9G8
Y Hargous, GM Hautbergue, AM Tintaru, L Skrisovska, AP Golovanov, ...
The EMBO journal 25 (21), 5126-5137, 2006
1942006
The catalytic mechanism of cytochrome P450 BM3 involves a 6 Å movement of the bound substrate on reduction
S Modi, MJ Sutcliffe, WU Primrose, LY Lian, GCK Roberts
Nature structural biology 3 (5), 414-417, 1996
1691996
The catalytic mechanism of beta-lactamases: NMR titration of an active-site lysine residue of the TEM-1 enzyme.
C Damblon, X Raquet, LY Lian, J Lamotte-Brasseur, E Fonze, P Charlier, ...
Proceedings of the National Academy of Sciences 93 (5), 1747-1752, 1996
1611996
A modulator of rho family G proteins, rhoGDI, binds these G proteins via an immunoglobulin-like domain and a flexible N-terminal arm
NH Keep, M Barnes, I Barsukov, R Badii, LY Lian, AW Segal, PCE Moody, ...
Structure 5 (5), 623-633, 1997
1601997
Labelling approaches for protein structural studies by solution-state and solid-state NMR
LY Lian, DA Middleton
Progress in Nuclear Magnetic Resonance Spectroscopy 39 (3), 171-190, 2001
1562001
NMR studies of substrate binding to cytochrome P450 BM3: comparisons to cytochrome P450 cam
S Modi, WU Primrose, JMB Boyle, CF Gibson, LY Lian, GCK Roberts
Biochemistry 34 (28), 8982-8988, 1995
1501995
Isolation and characterisation of two degradation products derived from the peptide antibiotic nisin
WC Chan, BW Bycroft, LY Lian, GCK Roberts
FEBS letters 252 (1-2), 29-36, 1989
1491989
Structure‐activity relationships in the peptide antibiotic nisin: antibacterial activity of fragments of nisin
WC Chan, M Leyland, J Clark, HM Dodd, LY Lian, MJ Gasson, BW Bycroft, ...
FEBS letters 390 (2), 129-132, 1996
1451996
[23] Protein-ligand interactions: Exchange processes and determination of ligand conformation and protein-ligand contacts
LY Lian, IL Barsukov, MJ Sutcliffe, KH Sze, GCK Roberts
Methods in enzymology 239, 657-700, 1994
1371994
Crystal structure of the FMN-binding domain of human cytochrome P450 reductase at 1.93 Å resolution
Q Zhao, S Modi, G Smith, M Paine, PD McDONAGH, CR Wolf, D Tew, ...
Protein science 8 (2), 298-306, 1999
1231999
Structure-activity relationships in the peptide antibiotic nisin: role of dehydroalanine 5
WC Chan, HM Dodd, N Horn, K Maclean, LY Lian, BW Bycroft, MJ Gasson, ...
Applied and environmental microbiology 62 (8), 2966-2969, 1996
1211996
1-Methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine as a Substrate of Cytochrome P450 2D6: Allosteric Effects of NADPH− Cytochrome P450 Reductase
S Modi, DE Gilham, MJ Sutcliffe, LY Lian, WU Primrose, CR Wolf, ...
Biochemistry 36 (15), 4461-4470, 1997
1171997
Engineering the substrate specificity of Bacillus megaterium cytochrome P-450 BM3: hydroxylation of alkyl trimethylammonium compounds
FC OLIVER, S Modi, UW PRIMROSE, LY Lian, CKG ROBERTS
Biochemical Journal 327 (2), 537-544, 1997
1121997
Model for the complex between protein G and an antibody Fc fragment in solution
K Kato, LY Lian, IL Barsukov, JP Derrick, HH Kim, R Tanaka, A Yoshino, ...
Structure 3 (1), 79-85, 1995
1111995
Localization of dynein light chains 1 and 2 and their pro-apoptotic ligands
CL Day, H Puthalakath, G Skea, A Strasser, I Barsukov, LY Lian, ...
Biochemical Journal 377 (3), 597-605, 2004
1042004
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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