CRISPR-Cas12a-assisted nucleic acid detection SY Li, QX Cheng, JM Wang, XY Li, ZL Zhang, S Gao, RB Cao, GP Zhao, ... Cell discovery 4 (1), 20, 2018 | 973 | 2018 |
CRISPR-Cas12a has both cis- and trans-cleavage activities on single-stranded DNA SY Li, QX Cheng, JK Liu, XQ Nie, GP Zhao, J Wang Cell research 28 (4), 491-493, 2018 | 693 | 2018 |
CRISPR/Cas systems towards next-generation biosensing Y Li, S Li, J Wang, G Liu Trends in biotechnology 37 (7), 730-743, 2019 | 681 | 2019 |
HOLMESv2: a CRISPR-Cas12b-assisted platform for nucleic acid detection and DNA methylation quantitation L Li, S Li, N Wu, J Wu, G Wang, G Zhao, J Wang ACS synthetic biology 8 (10), 2228-2237, 2019 | 472 | 2019 |
Multiplex gene regulation by CRISPR-ddCpf1 X Zhang, J Wang, Q Cheng, X Zheng, G Zhao, J Wang Cell discovery 3 (1), 1-9, 2017 | 199 | 2017 |
Characterization of a New GlnR Binding Box in the Promoter of amtB in Streptomyces coelicolor Inferred a PhoP/GlnR Competitive Binding Mechanism for Transcriptional … Y Wang, XF Cen, GP Zhao, J Wang Journal of bacteriology 194 (19), 5237-5244, 2012 | 167 | 2012 |
Complete genome sequence of the rifamycin SV-producing Amycolatopsis mediterranei U32 revealed its genetic characteristics in phylogeny and metabolism W Zhao, Y Zhong, H Yuan, J Wang, H Zheng, Y Wang, X Cen, F Xu, J Bai, ... Cell research 20 (10), 1096-1108, 2010 | 130 | 2010 |
The CCTL (Cpf1-assisted Cutting and Taq DNA ligase-assisted Ligation) method for efficient editing of large DNA constructs in vitro C Lei, SY Li, JK Liu, X Zheng, GP Zhao, J Wang Nucleic acids research 45 (9), e74-e74, 2017 | 86 | 2017 |
The MASTER (methylation-assisted tailorable ends rational) ligation method for seamless DNA assembly WH Chen, ZJ Qin, J Wang, GP Zhao Nucleic Acids Research 41 (8), e93-e93, 2013 | 82 | 2013 |
CRISPR-Cas12a-Mediated Gene Deletion and Regulation in Clostridium ljungdahlii and Its Application in Carbon Flux Redirection in Synthesis Gas Fermentation R Zhao, Y Liu, H Zhang, C Chai, J Wang, W Jiang, Y Gu ACS Synthetic Biology 8 (10), 2270-2279, 2019 | 66 | 2019 |
C-Brick: a new standard for assembly of biological parts using Cpf1 SY Li, GP Zhao, J Wang ACS synthetic biology 5 (12), 1383-1388, 2016 | 63 | 2016 |
GlnR positively regulates nasA transcription in Streptomyces coelicolor J Wang, GP Zhao Biochemical and Biophysical Research Communications 386 (1), 77-81, 2009 | 58 | 2009 |
A novel and efficient method for bacteria genome editing employing both CRISPR/Cas9 and an antibiotic resistance cassette H Zhang, QX Cheng, AM Liu, GP Zhao, J Wang Frontiers in Microbiology 8, 812, 2017 | 52 | 2017 |
An efficient system for deletion of large DNA fragments in Escherichia coli via introduction of both Cas9 and the non-homologous end joining system from Mycobacterium smegmatis X Zheng, SY Li, GP Zhao, J Wang Biochemical and biophysical research communications 485 (4), 768-774, 2017 | 51 | 2017 |
TB-QUICK: CRISPR-Cas12b-assisted rapid and sensitive detection of Mycobacterium tuberculosis IK Sam, YY Chen, J Ma, SY Li, RY Ying, LX Li, P Ji, S Wang, J Xu, Y Bao, ... Journal of Infection 83 (1), 54-60, 2021 | 43 | 2021 |
Atypical OmpR/PhoB subfamily response regulator GlnR of actinomycetes functions as a homodimer, stabilized by the unphosphorylated conserved Asp-focused charge interactions W Lin, Y Wang, X Han, Z Zhang, C Wang, J Wang, H Yang, Y Lu, W Jiang, ... Journal of Biological Chemistry 289 (22), 15413-15425, 2014 | 38 | 2014 |
Reprogrammable CRISPR/dCas9-based recruitment of DNMT1 for site-specific DNA demethylation and gene regulation A Lu, J Wang, W Sun, W Huang, Z Cai, G Zhao, J Wang Cell Discovery 5 (1), 22, 2019 | 37 | 2019 |
A CRISPR-Cas12a-based specific enhancer for more sensitive detection of SARS-CoV-2 infection W Huang, L Yu, D Wen, D Wei, Y Sun, H Zhao, Y Ye, W Chen, Y Zhu, ... EBioMedicine 61, 2020 | 36 | 2020 |
iBrick: a new standard for iterative assembly of biological parts with homing endonucleases JK Liu, WH Chen, SX Ren, GP Zhao, J Wang PloS one 9 (10), e110852, 2014 | 35 | 2014 |
DNA Cleavage is Independent of Synapsis during Streptomyces Phage φBT1 Integrase-Mediated Site-Specific Recombination L Zhang, L Wang, J Wang, X Ou, G Zhao, X Ding Journal of molecular cell biology 2 (5), 264-275, 2010 | 31 | 2010 |