Tooraj Mirshahi
Tooraj Mirshahi
Weis Center for Research, Geisinger Clinic
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PIP2 activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents
H Zhang, LC Craciun, T Mirshahi, T Rohcs, CMB Lopes, T Jin, ...
Neuron 37 (6), 963-975, 2003
Preassociation of calmodulin with voltage-gated Ca2+ channels revealed by FRET in single living cells
MG Erickson, BA Alseikhan, BZ Peterson, DT Yue
Neuron 31 (6), 973-985, 2001
Activation of inwardly rectifying K+ channels by distinct PtdIns (4, 5) P 2 interactions
H Zhang, C He, X Yan, T Mirshahi, DE Logothetis
Nature cell biology 1 (3), 183-188, 1999
Receptor-mediated hydrolysis of plasma membrane messenger PIP 2 leads to K+-current desensitization
E Kobrinsky, T Mirshahi, H Zhang, T Jin, DE Logothetis
Nature cell biology 2 (8), 507-514, 2000
Characteristic interactions with phosphatidylinositol 4, 5-bisphosphate determine regulation of kir channels by diverse modulators
X Du, H Zhang, C Lopes, T Mirshahi, T Rohacs, DE Logothetis
Journal of Biological Chemistry 279 (36), 37271-37281, 2004
Effects of the Abused Solvent Toluene on Recombinant N-Methyl-d-Aspartate and non-N-Methyl-d-Aspartate Receptors Expressed inXenopus Oocytes
SL Cruz, T Mirshahi, B Thomas, RL Balster, JJ Woodward
Journal of Pharmacology and Experimental Therapeutics 286 (1), 334-340, 1998
A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease
NS Abul-Husn, X Cheng, AH Li, Y Xin, C Schurmann, P Stevis, Y Liu, ...
New England Journal of Medicine 378 (12), 1096-1106, 2018
Ethanol sensitivity of heteromeric NMDA receptors: effects of subunit assembly, glycine and NMDAR1 Mg2+-insensitive mutants
T Mirshahi, JJ Woodward
Neuropharmacology 34 (3), 347-355, 1995
Ethanol inhibition ofN-methyl-d-aspartate receptors is reduced by site-directed mutagenesis of a transmembrane domain phenylalanine residue
KM Ronald, T Mirshahi, JJ Woodward
Journal of Biological Chemistry 276 (48), 44729-44735, 2001
The βγ subunits of G proteins gate a K+ channel by pivoted bending of a transmembrane segment
T Jin, L Peng, T Mirshahi, T Rohacs, KW Chan, R Sanchez, DE Logothetis
Molecular cell 10 (3), 469-481, 2002
Identification of a potassium channel site that interacts with G protein βγ subunits to mediate agonist-induced signaling
C He, H Zhang, T Mirshahi, DE Logothetis
Journal of Biological Chemistry 274 (18), 12517-12524, 1999
Clinical factors associated with weight loss outcomes after Roux‐en‐Y gastric bypass surgery
CD Still, GC Wood, X Chu, C Manney, W Strodel, A Petrick, J Gabrielsen, ...
Obesity 22 (3), 888-894, 2014
Identification of critical residues controlling G protein-gated inwardly rectifying K+ channel activity through interactions with the βγ subunits of G proteins
C He, X Yan, H Zhang, T Mirshahi, T Jin, A Huang, DE Logothetis
Journal of Biological Chemistry 277 (8), 6088-6096, 2002
High allelic burden of four obesity SNPs is associated with poorer weight loss outcomes following gastric bypass surgery
CD Still, GC Wood, X Chu, R Erdman, CH Manney, PN Benotti, AT Petrick, ...
Obesity 19 (8), 1676-1683, 2011
Effects of Acute and Chronic Ethanol Exposure on Heteromeric N‐Methyl‐d‐Aspartate Receptors Expressed in HEK 293 Cells
T Blevins, T Mirshahi, LJ Chandler, JJ Woodward
Journal of neurochemistry 69 (6), 2345-2354, 1997
Distinct sites on G protein βγ subunits regulate different effector functions
T Mirshahi, V Mittal, H Zhang, ME Linder, DE Logothetis
Journal of Biological Chemistry 277 (39), 36345-36350, 2002
Increased agonist and antagonist sensitivity of N-methyl-D-aspartate stimulated calcium flux in cultured neurons following chronic ethanol exposure
T Blevins, T Mirshahi, JJ Woodward
Neuroscience letters 200 (3), 214-218, 1995
Weight-independent effects of roux-en-Y gastric bypass on glucose homeostasis via melanocortin-4 receptors in mice and humans
JF Zechner, UL Mirshahi, S Satapati, ED Berglund, J Rossi, MM Scott, ...
Gastroenterology 144 (3), 580-590. e7, 2013
The MC4R(I251L) Allele Is Associated with Better Metabolic Status and More Weight Loss after Gastric Bypass Surgery
UL Mirshahi, CD Still, KK Masker, GS Gerhard, DJ Carey, T Mirshahi
The Journal of Clinical Endocrinology & Metabolism 96 (12), E2088-E2096, 2011
Phosphatidylinositol-4, 5-bisphosphate regulates NMDA receptor activity through α-actinin
IE Michailidis, TD Helton, VI Petrou, T Mirshahi, MD Ehlers, DE Logothetis
Journal of Neuroscience 27 (20), 5523-5532, 2007
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