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Tooraj Mirshahi
Tooraj Mirshahi
Weis Center for Research, Geisinger Clinic
Email verificata su geisinger.edu
Titolo
Citata da
Citata da
Anno
Mapping the human genetic architecture of COVID-19
Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ...
Nature 600 (7889), 472-477, 2021
7162021
A Protein-Truncating HSD17B13 Variant and Protection from Chronic Liver Disease
NS Abul-Husn, X Cheng, AH Li, Y Xin, C Schurmann, P Stevis, Y Liu, ...
New England Journal of Medicine 378 (12), 1096-1106, 2018
6782018
PIP2 activates KCNQ channels, and its hydrolysis underlies receptor-mediated inhibition of M currents
H Zhang, LC Craciun, T Mirshahi, T Rohács, CMB Lopes, T Jin, ...
Neuron 37 (6), 963-975, 2003
5962003
Activation of inwardly rectifying K+ channels by distinct PtdIns (4, 5) P2 interactions
H Zhang, C He, X Yan, T Mirshahi, DE Logothetis
Nature cell biology 1 (3), 183-188, 1999
3921999
Receptor-mediated hydrolysis of plasma membrane messenger PIP2 leads to K+-current desensitization
E Kobrinsky, T Mirshahi, H Zhang, T Jin, DE Logothetis
Nature cell biology 2 (8), 507-514, 2000
2622000
Characteristic interactions with phosphatidylinositol 4, 5-bisphosphate determine regulation of kir channels by diverse modulators
X Du, H Zhang, C Lopes, T Mirshahi, T Rohacs, DE Logothetis
Journal of Biological Chemistry 279 (36), 37271-37281, 2004
2282004
Whole-genome sequencing reveals host factors underlying critical COVID-19
A Kousathanas, E Pairo-Castineira, K Rawlik, A Stuckey, CA Odhams, ...
Nature 607 (7917), 97-103, 2022
2202022
Effects of the Abused Solvent Toluene on Recombinant N-Methyl-d-Aspartate and non-N-Methyl-d-Aspartate Receptors Expressed inXenopus Oocytes
SL Cruz, T Mirshahi, B Thomas, RL Balster, JJ Woodward
Journal of Pharmacology and Experimental Therapeutics 286 (1), 334-340, 1998
2101998
Ethanol sensitivity of heteromeric NMDA receptors: effects of subunit assembly, glycine and NMDAR1 Mg2+-insensitive mutants
T Mirshahi, JJ Woodward
Neuropharmacology 34 (3), 347-355, 1995
1771995
Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity
P Akbari, A Gilani, O Sosina, JA Kosmicki, L Khrimian, YY Fang, ...
Science 373 (6550), eabf8683, 2021
1602021
Clinical factors associated with weight loss outcomes after Roux‐en‐Y gastric bypass surgery
CD Still, GC Wood, X Chu, C Manney, W Strodel, A Petrick, J Gabrielsen, ...
Obesity 22 (3), 888-894, 2014
1532014
The βγ subunits of G proteins gate a K+ channel by pivoted bending of a transmembrane segment
T Jin, L Peng, T Mirshahi, T Rohacs, KW Chan, R Sanchez, DE Logothetis
Molecular cell 10 (3), 469-481, 2002
1492002
Identification of a potassium channel site that interacts with G protein βγ subunits to mediate agonist-induced signaling
C He, H Zhang, T Mirshahi, DE Logothetis
Journal of Biological Chemistry 274 (18), 12517-12524, 1999
1461999
Ethanol inhibition ofN-methyl-d-aspartate receptors is reduced by site-directed mutagenesis of a transmembrane domain phenylalanine residue
KM Ronald, T Mirshahi, JJ Woodward
Journal of Biological Chemistry 276 (48), 44729-44735, 2001
1432001
Gastric bypass surgery produces a durable reduction in cardiovascular disease risk factors and reduces the long‐term risks of congestive heart failure
PN Benotti, GC Wood, DJ Carey, VC Mehra, T Mirshahi, MR Lent, ...
Journal of the American Heart Association 6 (5), e005126, 2017
1302017
ALG9 mutation carriers develop kidney and liver cysts
W Besse, AR Chang, JZ Luo, WJ Triffo, BS Moore, A Gulati, DN Hartzel, ...
Journal of the American Society of Nephrology 30 (11), 2091-2102, 2019
1252019
Genetic inactivation of ANGPTL4 improves glucose homeostasis and is associated with reduced risk of diabetes
V Gusarova, C O’Dushlaine, TM Teslovich, PN Benotti, T Mirshahi, ...
Nature communications 9 (1), 2252, 2018
1252018
High allelic burden of four obesity SNPs is associated with poorer weight loss outcomes following gastric bypass surgery
CD Still, GC Wood, X Chu, R Erdman, CH Manney, PN Benotti, AT Petrick, ...
Obesity 19 (8), 1676-1683, 2011
1192011
Cilia have high cAMP levels that are inhibited by Sonic Hedgehog-regulated calcium dynamics
BS Moore, AN Stepanchick, PH Tewson, CM Hartle, J Zhang, AM Quinn, ...
Proceedings of the National Academy of Sciences 113 (46), 13069-13074, 2016
1132016
Identification of critical residues controlling G protein-gated inwardly rectifying K+ channel activity through interactions with the βγ subunits of G proteins
C He, X Yan, H Zhang, T Mirshahi, T Jin, A Huang, DE Logothetis
Journal of Biological Chemistry 277 (8), 6088-6096, 2002
1122002
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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