| Next generation of fluorine-containing pharmaceuticals, compounds currently in phase II–III clinical trials of major pharmaceutical companies: new structural trends and … Y Zhou, J Wang, Z Gu, S Wang, W Zhu, JL Aceña, VA Soloshonok, ... Chemical reviews 116 (2), 422-518, 2016 | 2376 | 2016 |
| Recent advances in the trifluoromethylation methodology and new CF3-containing drugs W Zhu, J Wang, S Wang, Z Gu, JL Aceña, K Izawa, H Liu, VA Soloshonok Journal of Fluorine Chemistry 167, 37-54, 2014 | 453 | 2014 |
| AlphaFold accelerates artificial intelligence powered drug discovery: efficient discovery of a novel CDK20 small molecule inhibitor F Ren, X Ding, M Zheng, M Korzinkin, X Cai, W Zhu, A Mantsyzov, ... Chemical Science 14 (6), 1443-1452, 2023 | 105 | 2023 |
| Nickel-Catalyzed ortho-C-H Thiolation of N-Benzoyl α-Amino Acid Derivatives F Gao, W Zhu, D Zhang, S Li, J Wang, H Liu The Journal of Organic Chemistry 81 (19), 9122-9130, 2016 | 57 | 2016 |
| Copper-mediated C–H (sp 2)/C–H (sp 3) coupling of benzoic acid derivatives with ethyl cyanoacetate: an expedient route to an isoquinolinone scaffold W Zhu, D Zhang, N Yang, H Liu Chemical communications 50 (73), 10634-10636, 2014 | 57 | 2014 |
| Visible-light-induced trifluoromethylation of highly functionalized arenes and heteroarenes in continuous flow I Abdiaj, C Bottecchia, J Alcazar, T Noёl Synthesis 49 (22), 4978-4985, 2017 | 55 | 2017 |
| Cu (II)-catalyzed C6-selective C–H thiolation of 2-pyridones using air as the oxidant P Peng, J Wang, C Li, W Zhu, H Jiang, H Liu RSC advances 6 (62), 57441-57445, 2016 | 51 | 2016 |
| Highly Enantioselective Michael Addition of 2‐Oxindole‐ 3‐carboxylate Esters to Nitroolefins Promoted by Cinchona Alkaloid‐Thiourea‐Brønsted Acid Cocatalysts X Chen, W Zhu, W Qian, E Feng, Y Zhou, J Wang, H Jiang, ZJ Yao, H Liu Advanced Synthesis & Catalysis 354 (11‐12), 2151-2156, 2012 | 44 | 2012 |
| Palladium-Catalyzed Ortho-Alkoxylation of N-Benzoyl α-Amino Acid Derivatives at Room Temperature S Li, W Zhu, F Gao, C Li, J Wang, H Liu The Journal of Organic Chemistry 82 (1), 126-134, 2017 | 28 | 2017 |
| Design, Synthesis, and Biological Evaluation of Novel Imidazo[1,2-a]pyridine Derivatives as Potent c-Met Inhibitors C Li, J Ai, D Zhang, X Peng, X Chen, Z Gao, Y Su, W Zhu, Y Ji, X Chen, ... ACS medicinal chemistry letters 6 (5), 507-512, 2015 | 28 | 2015 |
| Design, synthesis, and pharmacological evaluation of novel multisubstituted pyridin-3-amine derivatives as multitargeted protein kinase inhibitors for the treatment of non … W Zhu, H Chen, Y Wang, J Wang, X Peng, X Chen, Y Gao, C Li, Y He, J Ai, ... Journal of medicinal chemistry 60 (14), 6018-6035, 2017 | 27 | 2017 |
| Metal-Free Iodoperfluoroalkylation: Photocatalysis versus Frustrated Lewis Pair Catalysis L Helmecke, M Spittler, BM Schmidt, C Czekelius Synthesis 53 (01), 123-134, 2021 | 21 | 2021 |
| A remarkable difference that one fluorine atom confers on the mechanisms of inactivation of human ornithine aminotransferase by two cyclohexene analogues of γ-aminobutyric acid W Zhu, PF Doubleday, DS Catlin, PM Weerawarna, A Butrin, S Shen, ... Journal of the American Chemical Society 142 (10), 4892-4903, 2020 | 21 | 2020 |
| Pd (II)-catalyzed direct functionalization of C–H bonds of benzamides for synthesis of 1, 1-difluoro-1-alkenes C Li, D Zhang, W Zhu, P Wan, H Liu Organic Chemistry Frontiers 3 (9), 1080-1083, 2016 | 19 | 2016 |
| Direct catalytic asymmetric mannich-type reaction of an α-cf3 amide to isatin imines JS Yu, H Noda, N Kumagai, M Shibasaki Synlett 30 (04), 488-492, 2019 | 18 | 2019 |
| The facile construction of the phthalazin-1 (2H)-one scaffold via copper-mediated C–H (sp2)/C–H (sp) coupling under mild conditions W Zhu, B Wang, S Zhou, H Liu Beilstein Journal of Organic Chemistry 11 (1), 1624-1631, 2015 | 16 | 2015 |
| Palladium‐Catalyzed C2‐Acylation of Indoles with α‐Diketones Assisted by the Removable N‐(2‐Pyrimidyl) Group C Li, W Zhu, S Shu, X Wu, H Liu European Journal of Organic Chemistry 2015 (17), 3743-3750, 2015 | 16 | 2015 |
| Rational design and development of novel CDK9 inhibitors for the treatment of acute myeloid leukemia X Han, N Song, A Saidahmatov, P Wang, Y Wang, X Hu, W Kan, W Zhu, ... Journal of Medicinal Chemistry 64 (19), 14647-14663, 2021 | 15 | 2021 |
| [3+ 2] Cycloaddition of Trifluoromethylated N-Acylhydrazones with Maleates: Synthesis of Trifluoromethylated Pyrazolidines L Wen, D Huang, KH Wang, Y Wang, L Liu, Z Yang, Y Su, Y Hu Synthesis 50 (10), 1979-1990, 2018 | 15 | 2018 |
| Structure–activity relationship study of indolin-5-yl-cyclopropanamine derivatives as selective lysine specific demethylase 1 (LSD1) inhibitors C Li, M Su, W Zhu, W Kan, T Ge, G Xu, S Wang, L Sheng, F Gao, Y Ye, ... Journal of Medicinal Chemistry 65 (5), 4335-4349, 2022 | 13 | 2022 |
