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Adriana Carino
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The bile acid receptor GPBAR1 regulates the M1/M2 phenotype of intestinal macrophages and activation of GPBAR1 rescues mice from murine colitis
M Biagioli, A Carino, S Cipriani, D Francisci, S Marchianò, P Scarpelli, ...
The Journal of Immunology 199 (2), 718-733, 2017
2162017
Bile acids and their receptors in metabolic disorders
S Fiorucci, E Distrutti, A Carino, A Zampella, M Biagioli
Progress in Lipid Research 82, 101094, 2021
1392021
Bile acid signaling in inflammatory bowel diseases
S Fiorucci, A Carino, M Baldoni, L Santucci, E Costanzi, L Graziosi, ...
Digestive Diseases and Sciences 66, 674-693, 2021
1332021
BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis
A Carino, S Cipriani, S Marchianò, M Biagioli, C Santorelli, A Donini, ...
Scientific Reports 7 (1), 42801, 2017
1162017
Hijacking SARS-CoV-2/ACE2 receptor interaction by natural and semi-synthetic steroidal agents acting on functional pockets on the receptor binding domain
A Carino, F Moraca, B Fiorillo, S Marchianò, V Sepe, M Biagioli, ...
Frontiers in Chemistry 8, 572885, 2020
1012020
The bile acid sensor FXR is required for immune-regulatory activities of TLR-9 in intestinal inflammation
B Renga, A Mencarelli, S Cipriani, C D'Amore, A Carino, A Bruno, ...
PLoS One 8 (1), e54472, 2013
972013
Exploitation of cholane scaffold for the discovery of potent and selective farnesoid X receptor (FXR) and G-protein coupled bile acid receptor 1 (GP-BAR1) ligands
C Festa, B Renga, C D’Amore, V Sepe, C Finamore, S De Marino, ...
Journal of medicinal chemistry 57 (20), 8477-8495, 2014
852014
Role of TGR5 (GPBAR1) in liver disease
V Keitel, D Häussinger
Seminars in liver disease 38 (04), 333-339, 2018
832018
Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and …
B Renga, S Cipriani, A Carino, M Simonetti, A Zampella, S Fiorucci
PloS one 10 (11), e0141082, 2015
642015
Bile acids activated receptors in inflammatory bowel disease
M Biagioli, S Marchianò, A Carino, C Di Giorgio, L Santucci, E Distrutti, ...
Cells 10 (6), 1281, 2021
562021
Cystathionine γ-lyase, a H2S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids
B Renga, M Bucci, S Cipriani, A Carino, MC Monti, A Zampella, ...
American Journal of Physiology-Heart and Circulatory Physiology 309 (1 …, 2015
542015
The bile acid receptor GPBAR1 (TGR5) is expressed in human gastric cancers and promotes epithelial-mesenchymal transition in gastric cancer cell lines
A Carino, L Graziosi, C D'Amore, S Cipriani, S Marchianò, E Marino, ...
Oncotarget 7 (38), 61021, 2016
522016
Metabolic variability of a multispecies probiotic preparation impacts on the anti-inflammatory activity
M Biagioli, L Laghi, A Carino, S Cipriani, E Distrutti, S Marchianò, ...
Frontiers in pharmacology 8, 505, 2017
512017
Impaired itching perception in murine models of cholestasis is supported by dysregulation of GPBAR1 signaling
S Cipriani, B Renga, C D’Amore, M Simonetti, AA De Tursi, A Carino, ...
PLoS One 10 (7), e0129866, 2015
502015
Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis
A Carino, S Marchiano, M Biagioli, M Bucci, V Vellecco, V Brancaleone, ...
The FASEB Journal 33 (2), 2809-2822, 2019
492019
Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists
V Sepe, C Festa, B Renga, A Carino, S Cipriani, C Finamore, D Masullo, ...
Scientific reports 6 (1), 19008, 2016
492016
Signaling from intestine to the host: how bile acids regulate intestinal and liver immunity
M Biagioli, A Carino
Bile Acids and Their Receptors, 95-108, 2019
472019
Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice
A Carino, S Cipriani, S Marchianò, M Biagioli, P Scarpelli, A Zampella, ...
Scientific reports 7 (1), 13689, 2017
452017
Ursodeoxycholic acid is a GPBAR1 agonist and resets liver/intestinal FXR signaling in a model of diet-induced dysbiosis and NASH
A Carino, M Biagioli, S Marchianò, C Fiorucci, A Zampella, MC Monti, ...
Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2019
432019
GPBAR1 functions as gatekeeper for liver NKT cells and provides counterregulatory signals in mouse models of immune-mediated hepatitis
M Biagioli, A Carino, C Fiorucci, S Marchianò, C Di Giorgio, R Roselli, ...
Cellular and Molecular Gastroenterology and Hepatology 8 (3), 447-473, 2019
432019
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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