The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups C Curtis, SP Shah, SF Chin, G Turashvili, OM Rueda, MJ Dunning, ... Nature 486 (7403), 346-352, 2012 | 6172 | 2012 |
The clonal and mutational evolution spectrum of primary triple-negative breast cancers SP Shah, A Roth, R Goya, A Oloumi, G Ha, Y Zhao, G Turashvili, J Ding, ... Nature 486 (7403), 395-399, 2012 | 2317 | 2012 |
Somatic mutations altering EZH2 (Tyr641) in follicular and diffuse large B-cell lymphomas of germinal-center origin RD Morin, NA Johnson, TM Severson, AJ Mungall, J An, R Goya, JE Paul, ... Nature genetics 42 (2), 181-185, 2010 | 1998 | 2010 |
ARID1A mutations in endometriosis-associated ovarian carcinomas KC Wiegand, SP Shah, OM Al-Agha, Y Zhao, K Tse, T Zeng, J Senz, ... New England Journal of Medicine 363 (16), 1532-1543, 2010 | 1956 | 2010 |
The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes B Pereira, SF Chin, OM Rueda, HKM Vollan, E Provenzano, HA Bardwell, ... Nature communications 7 (1), 1-16, 2016 | 1651 | 2016 |
Tumor-associated macrophages and survival in classic Hodgkin's lymphoma C Steidl, T Lee, SP Shah, P Farinha, G Han, T Nayar, A Delaney, ... New England Journal of Medicine 362 (10), 875-885, 2010 | 1489 | 2010 |
Mutational evolution in a lobular breast tumour profiled at single nucleotide resolution SP Shah, RD Morin, J Khattra, L Prentice, T Pugh, A Burleigh, A Delaney, ... Nature 461 (7265), 809-813, 2009 | 1342 | 2009 |
Eleven grand challenges in single-cell data science D Lähnemann, J Köster, E Szczurek, DJ McCarthy, SC Hicks, ... Genome biology 21, 1-35, 2020 | 1054 | 2020 |
PyClone: statistical inference of clonal population structure in cancer A Roth, J Khattra, D Yap, A Wan, E Laks, J Biele, G Ha, S Aparicio, ... Nature methods 11 (4), 396-398, 2014 | 1000 | 2014 |
Mutation of FOXL2 in granulosa-cell tumors of the ovary SP Shah, M Köbel, J Senz, RD Morin, BA Clarke, KC Wiegand, G Leung, ... New England Journal of Medicine 360 (26), 2719-2729, 2009 | 873 | 2009 |
Hereditary diffuse gastric cancer syndrome: CDH1 mutations and beyond S Hansford, P Kaurah, H Li-Chang, M Woo, J Senz, H Pinheiro, ... JAMA oncology 1 (1), 23-32, 2015 | 757 | 2015 |
MHC class II transactivator CIITA is a recurrent gene fusion partner in lymphoid cancers C Steidl, SP Shah, BW Woolcock, L Rui, M Kawahara, P Farinha, ... Nature 471 (7338), 377-381, 2011 | 702 | 2011 |
Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution P Eirew, A Steif, J Khattra, G Ha, D Yap, H Farahani, K Gelmon, S Chia, ... Nature 518 (7539), 422-426, 2015 | 666 | 2015 |
deFuse: an algorithm for gene fusion discovery in tumor RNA-Seq data A McPherson, F Hormozdiari, A Zayed, R Giuliany, G Ha, MGF Sun, ... PLoS computational biology 7 (5), e1001138, 2011 | 618 | 2011 |
Spatial genomic heterogeneity within localized, multifocal prostate cancer PC Boutros, M Fraser, NJ Harding, R De Borja, D Trudel, E Lalonde, ... Nature genetics 47 (7), 736-745, 2015 | 539 | 2015 |
CX-5461 is a DNA G-quadruplex stabilizer with selective lethality in BRCA1/2 deficient tumours H Xu, M Di Antonio, S McKinney, V Mathew, B Ho, NJ O’Neil, ND Santos, ... Nature communications 8 (1), 14432, 2017 | 528 | 2017 |
Multifocal clonal evolution characterized using circulating tumour DNA in a case of metastatic breast cancer M Murtaza, SJ Dawson, K Pogrebniak, OM Rueda, E Provenzano, J Grant, ... Nature communications 6 (1), 8760, 2015 | 527 | 2015 |
Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers A Heravi-Moussavi, MS Anglesio, SWG Cheng, J Senz, W Yang, ... New England Journal of Medicine 366 (3), 234-242, 2012 | 523 | 2012 |
Distinct evolutionary trajectories of primary high‐grade serous ovarian cancers revealed through spatial mutational profiling A Bashashati, G Ha, A Tone, J Ding, LM Prentice, A Roth, J Rosner, ... The Journal of pathology 231 (1), 21-34, 2013 | 503 | 2013 |
Mutational and structural analysis of diffuse large B-cell lymphoma using whole-genome sequencing RD Morin, K Mungall, E Pleasance, AJ Mungall, R Goya, RD Huff, ... Blood, The Journal of the American Society of Hematology 122 (7), 1256-1265, 2013 | 469 | 2013 |