|TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity|
A Caputo, E Caci, L Ferrera, N Pedemonte, C Barsanti, E Sondo, U Pfeffer, ...
Science 322 (5901), 590-594, 2008
|Thiazolidinone CFTR inhibitor identified by high-throughput screening blocks cholera toxin–induced intestinal fluid secretion|
T Ma, JR Thiagarajah, H Yang, ND Sonawane, C Folli, LJV Galietta, ...
The Journal of clinical investigation 110 (11), 1651-1658, 2002
|Small-molecule correctors of defective ΔF508-CFTR cellular processing identified by high-throughput screening|
N Pedemonte, GL Lukacs, K Du, E Caci, O Zegarra-Moran, LJV Galietta, ...
The Journal of clinical investigation 115 (9), 2564-2571, 2005
|Chloride channels as drug targets|
AS Verkman, LJV Galietta
Nature reviews Drug discovery 8 (2), 153-171, 2009
|Green fluorescent protein-based halide indicators with improved chloride and iodide affinities|
LJV Galietta, PM Haggie, AS Verkman
FEBS letters 499 (3), 220-224, 2001
|Structure and function of TMEM16 proteins (anoctamins)|
N Pedemonte, LJV Galietta
Physiological reviews, 2014
|Discovery of glycine hydrazide pore-occluding CFTR inhibitors: mechanism, structure–activity analysis, and in vivo efficacy|
C Muanprasat, ND Sonawane, D Salinas, A Taddei, LJV Galietta, ...
The Journal of general physiology 124 (2), 125-137, 2004
|Nanomolar affinity small molecule correctors of defective ΔF508-CFTR chloride channel gating|
H Yang, AA Shelat, RK Guy, VS Gopinath, T Ma, K Du, GL Lukacs, ...
Journal of Biological Chemistry 278 (37), 35079-35085, 2003
|Cell-based assay for high-throughput quantitative screening of CFTR chloride transport agonists|
LVJ Galietta, S Jayaraman, AS Verkman
American Journal of Physiology-Cell Physiology 281 (5), C1734-C1742, 2001
|High-affinity activators of cystic fibrosis transmembrane conductance regulator (CFTR) chloride conductance identified by high-throughput screening|
T Ma, L Vetrivel, H Yang, N Pedemonte, O Zegarra-Moran, LJV Galietta, ...
Journal of Biological Chemistry 277 (40), 37235-37241, 2002
|Novel CFTR chloride channel activators identified by screening of combinatorial libraries based on flavone and benzoquinolizinium lead compounds|
LJV Galietta, MF Springsteel, M Eda, EJ Niedzinski, K By, MJ Haddadin, ...
Journal of Biological Chemistry 276 (23), 19723-19728, 2001
|Regulation of TMEM16A chloride channel properties by alternative splicing|
L Ferrera, A Caputo, I Ubby, E Bussani, O Zegarra-Moran, R Ravazzolo, ...
Journal of Biological Chemistry 284 (48), 33360-33368, 2009
|Phenylglycine and sulfonamide correctors of defective ΔF508 and G551D cystic fibrosis transmembrane conductance regulator chloride-channel gating|
N Pedemonte, ND Sonawane, A Taddei, J Hu, O Zegarra-Moran, YF Suen, ...
Molecular pharmacology 67 (5), 1797-1807, 2005
|Contribution of CFTR to apical-basolateral fluid transport in cultured human alveolar epithelial type II cells|
X Fang, Y Song, J Hirsch, LJV Galietta, N Pedemonte, RL Zemans, ...
American Journal of Physiology-Lung Cellular and Molecular Physiology 290 (2 …, 2006
|IL-4 is a potent modulator of ion transport in the human bronchial epithelium in vitro|
LJV Galietta, P Pagesy, C Folli, E Caci, L Romio, B Costes, E Nicolis, ...
The Journal of Immunology 168 (2), 839-845, 2002
|Correction of delF508-CFTR activity with benzo (c) quinolizinium compounds through facilitation of its processing in cystic fibrosis airway cells|
RL Dormer, R Dérand, CM McNeilly, Y Mettey, L Bulteau-Pignoux, ...
Journal of cell science 114 (22), 4073-4081, 2001
|Thiocyanate transport in resting and IL-4-stimulated human bronchial epithelial cells: role of pendrin and anion channels|
N Pedemonte, E Caci, E Sondo, A Caputo, K Rhoden, U Pfeffer, ...
The Journal of Immunology 178 (8), 5144-5153, 2007
|Altered channel gating mechanism for CFTR inhibition by a high‐affinity thiazolidinone blocker|
A Taddei, C Folli, O Zegarra-Moran, P Fanen, AS Verkman, LJV Galietta
FEBS letters 558 (1-3), 52-56, 2004
|Evidence against the rescue of defective ΔF508-CFTR cellular processing by curcumin in cell culture and mouse models|
Y Song, ND Sonawane, D Salinas, L Qian, N Pedemonte, LJV Galietta, ...
Journal of Biological Chemistry 279 (39), 40629-40633, 2004
|Development of substituted benzo [c] quinolizinium compounds as novel activators of the cystic fibrosis chloride channel|
F Becq, Y Mettey, MA Gray, LJV Galietta, RL Dormer, M Merten, T Métayé, ...
Journal of Biological Chemistry 274 (39), 27415-27425, 1999