IRE1α inhibition decreased TXNIP/NLRP3 inflammasome activation through miR-17-5p after neonatal hypoxic–ischemic brain injury in rats DI Chen, BJ Dixon, DM Doycheva, B Li, Y Zhang, Q Hu, Y He, Z Guo, ... Journal of neuroinflammation 15, 1-18, 2018 | 160 | 2018 |
Delayed hyperbaric oxygen therapy promotes neurogenesis through reactive oxygen species/hypoxia-inducible factor-1α/β-catenin pathway in middle cerebral artery occlusion rats Q Hu, X Liang, D Chen, Y Chen, D Doycheva, J Tang, J Tang, JH Zhang Stroke 45 (6), 1807-1814, 2014 | 96 | 2014 |
G-CSF attenuates neuroinflammation and stabilizes the blood–brain barrier via the PI3K/Akt/GSK-3β signaling pathway following neonatal hypoxia-ischemia in rats L Li, DW McBride, D Doycheva, BJ Dixon, PR Krafft, JH Zhang, J Tang Experimental neurology 272, 135-144, 2015 | 95 | 2015 |
Ghrelin attenuates oxidative stress and neuronal apoptosis via GHSR-1α/AMPK/Sirt1/PGC-1α/UCP2 pathway in a rat model of neonatal HIE J Huang, W Liu, DM Doycheva, M Gamdzyk, W Lu, J Tang, JH Zhang Free Radical Biology and Medicine 141, 322-337, 2019 | 91 | 2019 |
Chemerin suppresses neuroinflammation and improves neurological recovery via CaMKK2/AMPK/Nrf2 pathway after germinal matrix hemorrhage in neonatal rats Y Zhang, N Xu, Y Ding, Y Zhang, Q Li, J Flores, M Haghighiabyaneh, ... Brain, behavior, and immunity 70, 179-193, 2018 | 75 | 2018 |
Long noncoding RNA AC003092. 1 promotes temozolomide chemosensitivity through miR-195/TFPI-2 signaling modulation in glioblastoma N Xu, B Liu, C Lian, DM Doycheva, Z Fu, Y Liu, J Zhou, Z He, Z Yang, ... Cell death & disease 9 (12), 1139, 2018 | 71 | 2018 |
Sestrin2, as a negative feedback regulator of mTOR, provides neuroprotection by activation AMPK phosphorylation in neonatal hypoxic-ischemic encephalopathy in rat pups X Shi, L Xu, DM Doycheva, J Tang, M Yan, JH Zhang Journal of Cerebral Blood Flow & Metabolism 37 (4), 1447-1460, 2017 | 71 | 2017 |
Adiponectin attenuates neuronal apoptosis induced by hypoxia-ischemia via the activation of AdipoR1/APPL1/LKB1/AMPK pathway in neonatal rats N Xu, Y Zhang, DM Doycheva, Y Ding, Y Zhang, J Tang, H Guo, JH Zhang Neuropharmacology 133, 415-428, 2018 | 69 | 2018 |
cGAS/STING pathway activation contributes to delayed neurodegeneration in neonatal hypoxia-ischemia rat model: possible involvement of LINE-1 M Gamdzyk, DM Doycheva, C Araujo, U Ocak, Y Luo, J Tang, JH Zhang Molecular neurobiology 57, 2600-2619, 2020 | 68 | 2020 |
Sestrin2 induced by hypoxia inducible factor1 alpha protects the blood-brain barrier via inhibiting VEGF after severe hypoxic-ischemic injury in neonatal rats X Shi, DM Doycheva, L Xu, J Tang, M Yan, JH Zhang Neurobiology of disease 95, 111-121, 2016 | 65 | 2016 |
Granulocyte-colony stimulating factor in combination with stem cell factor confers greater neuroprotection after hypoxic–ischemic brain damage in the neonatal rats than a … D Doycheva, G Shih, H Chen, R Applegate, JH Zhang, J Tang Translational stroke research 4, 171-178, 2013 | 65 | 2013 |
The MC4 receptor agonist RO27‐3225 inhibits NLRP1‐dependent neuronal pyroptosis via the ASK1/JNK/p38 MAPK pathway in a mouse model of intracerebral … S Chen, Y Zuo, L Huang, P Sherchan, J Zhang, Z Yu, J Peng, J Zhang, ... British Journal of Pharmacology 176 (9), 1341-1356, 2019 | 56 | 2019 |
Role of PPAR-β/δ/miR-17/TXNIP pathway in neuronal apoptosis after neonatal hypoxic-ischemic injury in rats M Gamdzyk, DM Doycheva, J Malaguit, B Enkhjargal, J Tang, JH Zhang Neuropharmacology 140, 150-161, 2018 | 54 | 2018 |
Chemerin reverses neurological impairments and ameliorates neuronal apoptosis through ChemR23/CAMKK2/AMPK pathway in neonatal hypoxic–ischemic encephalopathy Y Zhang, N Xu, Y Ding, DM Doycheva, Y Zhang, Q Li, J Flores, ... Cell death & disease 10 (2), 97, 2019 | 52 | 2019 |
Cannabinoid receptor type 2 agonist attenuates apoptosis by activation of phosphorylated CREB–Bcl-2 pathway after subarachnoid hemorrhage in rats M Fujii, P Sherchan, Y Soejima, Y Hasegawa, J Flores, D Doycheva, ... Experimental neurology 261, 396-403, 2014 | 51 | 2014 |
G-CSF ameliorates neuronal apoptosis through GSK-3β inhibition in neonatal hypoxia–ischemia in rats L Li, D Klebe, D Doycheva, DW McBride, PR Krafft, J Flores, C Zhou, ... Experimental neurology 263, 141-149, 2015 | 48 | 2015 |
Erythropoietin in stroke therapy: friend or foe R Souvenir, D Doycheva, J H Zhang, J Tang Current medicinal chemistry 22 (10), 1205-1213, 2015 | 44 | 2015 |
IRE1α inhibition attenuates neuronal pyroptosis via miR-125/NLRP1 pathway in a neonatal hypoxic-ischemic encephalopathy rat model J Huang, W Lu, DM Doycheva, M Gamdzyk, X Hu, R Liu, JH Zhang, ... Journal of Neuroinflammation 17, 1-15, 2020 | 40 | 2020 |
Delayed remote ischemic postconditioning improves long term sensory motor deficits in a neonatal hypoxic ischemic rat model PN Drunalini Perera, Q Hu, J Tang, L Li, M Barnhart, DM Doycheva, ... PloS one 9 (2), e90258, 2014 | 38 | 2014 |
CpG-ODN exerts a neuroprotective effect via the TLR9/pAMPK signaling pathway by activation of autophagy in a neonatal HIE rat model L Ye, Z Feng, D Doycheva, J Malaguit, B Dixon, N Xu, JH Zhang, J Tang Experimental neurology 301, 70-80, 2018 | 29 | 2018 |