Telomeric DNA damage is irreparable and causes persistent DNA-damage-response activation M Fumagalli, F Rossiello, M Clerici, S Barozzi, D Cittaro, JM Kaplunov, ... Nature cell biology 14 (4), 355-365, 2012 | 888 | 2012 |
The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast V Paciotti, M Clerici, G Lucchini, MP Longhese Genes & development 14 (16), 2046-2059, 2000 | 344 | 2000 |
The Saccharomyces cerevisiae Sae2 protein promotes resection and bridging of double strand break ends M Clerici, D Mantiero, G Lucchini, MP Longhese Journal of Biological Chemistry 280 (46), 38631-38638, 2005 | 255 | 2005 |
The Yku70–Yku80 complex contributes to regulate double‐strand break processing and checkpoint activation during the cell cycle M Clerici, D Mantiero, I Guerini, G Lucchini, MP Longhese EMBO reports 9 (8), 810-818, 2008 | 203 | 2008 |
The Saccharomyces cerevisiae Sae2 protein negatively regulates DNA damage checkpoint signalling M Clerici, D Mantiero, G Lucchini, MP Longhese EMBO reports 7 (2), 212-218, 2006 | 175 | 2006 |
Multiple pathways regulate 3′ overhang generation at S. cerevisiae telomeres D Bonetti, M Martina, M Clerici, G Lucchini, MP Longhese Molecular cell 35 (1), 70-81, 2009 | 167 | 2009 |
Mechanisms and regulation of DNA end resection MP Longhese, D Bonetti, N Manfrini, M Clerici The EMBO journal 29 (17), 2864-2874, 2010 | 150 | 2010 |
Dual role for Saccharomyces cerevisiae Tel1 in the checkpoint response to double‐strand breaks D Mantiero, M Clerici, G Lucchini, MP Longhese EMBO reports 8 (4), 380-387, 2007 | 149 | 2007 |
Characterization of mec1 kinase-deficient mutants and of new hypomorphic mec1 alleles impairing subsets of the DNA damage response pathway V Paciotti, M Clerici, M Scotti, G Lucchini, MP Longhese Molecular and cellular biology, 2001 | 143 | 2001 |
Shelterin-like proteins and Yku inhibit nucleolytic processing of Saccharomyces cerevisiae telomeres D Bonetti, M Clerici, S Anbalagan, M Martina, G Lucchini, MP Longhese PLoS genetics 6 (5), e1000966, 2010 | 130 | 2010 |
DNA double-strand breaks in meiosis: checking their formation, processing and repair MP Longhese, D Bonetti, I Guerini, N Manfrini, M Clerici DNA repair 8 (9), 1127-1138, 2009 | 121 | 2009 |
The S-phase checkpoint and its regulation in Saccharomyces cerevisiae MP Longhese, M Clerici, G Lucchini Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 532 (1 …, 2003 | 117 | 2003 |
M ec1/ATR regulates the generation of single‐stranded DNA that attenuates T el1/ATM signaling at DNA ends M Clerici, C Trovesi, A Galbiati, G Lucchini, MP Longhese The EMBO journal 33 (3), 198-216, 2014 | 81 | 2014 |
A Tel1/MRX-dependent checkpoint inhibits the metaphase-to-anaphase transition after UV irradiation in the absence of Mec1 M Clerici, V Baldo, D Mantiero, F Lottersberger, G Lucchini, MP Longhese Molecular and cellular biology 24 (23), 10126-10144, 2004 | 69 | 2004 |
Tel1 and Rif2 regulate MRX functions in end-tethering and repair of DNA double-strand breaks C Cassani, E Gobbini, W Wang, H Niu, M Clerici, P Sung, MP Longhese PLoS biology 14 (2), e1002387, 2016 | 67 | 2016 |
The MRX complex plays multiple functions in resection of Yku-and Rif2-protected DNA ends D Bonetti, M Clerici, N Manfrini, G Lucchini, MP Longhese PloS one 5 (11), e14142, 2010 | 66 | 2010 |
The cellular response to chromosome breakage MP Longhese, D Mantiero, M Clerici Molecular microbiology 60 (5), 1099-1108, 2006 | 63 | 2006 |
Sae2 function at DNA double-strand breaks is bypassed by dampening Tel1 or Rad53 activity E Gobbini, M Villa, M Gnugnoli, L Menin, M Clerici, MP Longhese PLoS genetics 11 (11), e1005685, 2015 | 58 | 2015 |
Elevated levels of the polo kinase Cdc5 override the Mec1/ATR checkpoint in budding yeast by acting at different steps of the signaling pathway RA Donnianni, M Ferrari, F Lazzaro, M Clerici, B Tamilselvan Nachimuthu, ... PLoS genetics 6 (1), e1000763, 2010 | 55 | 2010 |
Hyperactivation of the yeast DNA damage checkpoint by TEL1 and DDC2 overexpression M Clerici, V Paciotti, V Baldo, M Romano, G Lucchini, MP Longhese The EMBO journal 20 (22), 6485-6498, 2001 | 50 | 2001 |