| A noncovalent class of papain-like protease/deubiquitinase inhibitors blocks SARS virus replication K Ratia, S Pegan, J Takayama, K Sleeman, M Coughlin, S Baliji, ... Proceedings of the National Academy of Sciences 105 (42), 16119-16124, 2008 | 486 | 2008 |
| Cytoplasmic domain structures of Kir2. 1 and Kir3. 1 show sites for modulating gating and rectification S Pegan, C Arrabit, W Zhou, W Kwiatkowski, A Collins, PA Slesinger, ... Nature neuroscience 8 (3), 279-287, 2005 | 334 | 2005 |
| Characterization and noncovalent inhibition of the deubiquitinase and deISGylase activity of SARS-CoV-2 papain-like protease BT Freitas, IA Durie, J Murray, JE Longo, HC Miller, D Crich, RJ Hogan, ... ACS infectious diseases 6 (8), 2099-2109, 2020 | 260 | 2020 |
| ISG15: it's complicated JV Dzimianski, FEM Scholte, É Bergeron, SD Pegan Journal of molecular biology 431 (21), 4203-4216, 2019 | 126 | 2019 |
| Structural insights into the interaction of coronavirus papain-like proteases and interferon-stimulated gene product 15 from different species CM Daczkowski, JV Dzimianski, JR Clasman, O Goodwin, AD Mesecar, ... Journal of molecular biology 429 (11), 1661-1683, 2017 | 116 | 2017 |
| Synthesis of casimiroin and optimization of its quinone reductase 2 and aromatase inhibitory activities A Maiti, PVN Reddy, M Sturdy, L Marler, SD Pegan, AD Mesecar, ... Journal of medicinal chemistry 52 (7), 1873-1884, 2009 | 98 | 2009 |
| Andersen's Syndrome Mutation Effects on the Structure and Assembly of the Cytoplasmic Domains of Kir2.1, S Pegan, C Arrabit, PA Slesinger, S Choe Biochemistry 45 (28), 8599-8606, 2006 | 97 | 2006 |
| Kir channel modulators SD Pegan, PA Slesinger, S Choe, P Aryal US Patent 8,097,422, 2012 | 84 | 2012 |
| Crimean-Congo hemorrhagic fever virus suppresses innate immune responses via a ubiquitin and ISG15 specific protease FEM Scholte, M Zivcec, JV Dzimianski, MK Deaton, JR Spengler, ... Cell reports 20 (10), 2396-2407, 2017 | 81 | 2017 |
| Blocking myristoylation of Src inhibits its kinase activity and suppresses prostate cancer progression S Kim, OA Alsaidan, O Goodwin, Q Li, E Sulejmani, Z Han, A Bai, T Albers, ... Cancer research 77 (24), 6950-6962, 2017 | 77 | 2017 |
| Structural analysis of a viral ovarian tumor domain protease from the Crimean-Congo hemorrhagic fever virus in complex with covalently bonded ubiquitin GC Capodagli, MA McKercher, EA Baker, EM Masters, JS Brunzelle, ... Journal of virology 85 (7), 3621-3630, 2011 | 77 | 2011 |
| An Antimicrobial Guanidine-Bearing Sesterterpene from the Cultured Cyanobacterium Scytonema sp. S Mo, A Krunic, SD Pegan, SG Franzblau, J Orjala Journal of natural products 72 (11), 2043-2045, 2009 | 74 | 2009 |
| Development and validation of a yeast high-throughput screen for inhibitors of Aβ42 oligomerization SK Park, SD Pegan, AD Mesecar, LM Jungbauer, MJ LaDu, SW Liebman Disease models & mechanisms 4 (6), 822-831, 2011 | 60 | 2011 |
| Diversity of ubiquitin and ISG15 specificity among nairoviruses' viral ovarian tumor domain proteases GC Capodagli, MK Deaton, EA Baker, RJ Lumpkin, SD Pegan Journal of virology 87 (7), 3815-3827, 2013 | 58 | 2013 |
| How ISG15 combats viral infection BT Freitas, FEM Scholte, É Bergeron, SD Pegan Virus research 286, 198036, 2020 | 57 | 2020 |
| A Noncompetitive Inhibitor for Mycobacterium tuberculosis’s Class IIa Fructose 1,6-Bisphosphate Aldolase GC Capodagli, WG Sedhom, M Jackson, KA Ahrendt, SD Pegan Biochemistry 53 (1), 202-213, 2014 | 57 | 2014 |
| Assessment of inhibitors of pathogenic Crimean-Congo hemorrhagic fever virus strains using virus-like particles M Zivcec, MG Metcalfe, CG Albariño, LW Guerrero, SD Pegan, ... PLoS neglected tropical diseases 9 (12), e0004259, 2015 | 50 | 2015 |
| Structural basis for catalysis of a tetrameric class IIa fructose 1, 6-bisphosphate aldolase from Mycobacterium tuberculosis SD Pegan, K Rukseree, SG Franzblau, AD Mesecar Journal of molecular biology 386 (4), 1038-1053, 2009 | 49 | 2009 |
| X‐ray structural studies of quinone reductase 2 nanomolar range inhibitors SD Pegan, M Sturdy, G Ferry, P Delagrange, JA Boutin, AD Mesecar Protein Science 20 (7), 1182-1195, 2011 | 47 | 2011 |
| Isolation and evaluation of kaempferol glycosides from the fern Neocheiropteris palmatopedata JH Yang, TP Kondratyuk, LE Marler, X Qiu, Y Choi, H Cao, R Yu, M Sturdy, ... Phytochemistry 71 (5-6), 641-647, 2010 | 46 | 2010 |
Andrew D. MesecarDistinguished Professor of Biochemistry, Purdue University, Department of BiochemistryVerified email at purdue.edu
