Current mathematical models for cancer drug discovery L Carrara, SM Lavezzi, E Borella, G De Nicolao, P Magni, I Poggesi Expert opinion on drug discovery 12 (8), 785-799, 2017 | 27 | 2017 |
Mathematical modeling of efficacy and safety for anticancer drugs clinical development SM Lavezzi, E Borella, L Carrara, G De Nicolao, P Magni, I Poggesi Expert Opinion on Drug Discovery 13 (1), 5-21, 2018 | 9 | 2018 |
Systemic Exposure of Rituximab Increased by Ibrutinib: Pharmacokinetic Results and Modeling Based on the HELIOS Trial SM Lavezzi, J de Jong, M Neyens, P Cramer, F Demirkan, G Fraser, ... Pharmaceutical research 36 (7), 93, 2019 | 5 | 2019 |
MPBPK-TMDD models for mAbs: alternative models, comparison, and identifiability issues SM Lavezzi, E Mezzalana, S Zamuner, G De Nicolao, P Ma, M Simeoni Journal of pharmacokinetics and pharmacodynamics 45 (6), 787-802, 2018 | 4 | 2018 |
The area under the effect curve as an efficacy determinant for anti‐infectives C Chen, SM Lavezzi, L Iavarone CPT: Pharmacometrics & Systems Pharmacology, 2022 | 3 | 2022 |
Concept and application of the probability of pharmacological success (PoPS) as a decision tool in drug development: a position paper C Chen, X Zhou, SM Lavezzi, U Arshad, R Sharma Journal of Translational Medicine 21 (1), 1-13, 2023 | 2 | 2023 |
Translational modelling and estimation of probability of molecule success on balance of pharmacology benefit and safety risk SM Lavezzi, C Chen, J Upson, J Toomey, K French, L Chen, A Lindsay | 2 | 2021 |
Assessing drug effect from distributional data: a population approach with application to Duchenne Muscular Dystrophy treatment SM Lavezzi, M Rocchetti, P Bettica, S Petrini, G De Nicolao Computer Methods and Programs in Biomedicine, 2019 | 2 | 2019 |
Systemic Exposure of Rituximab Increased By Ibrutinib: Pharmacokinetic Results from the Helios Trial P Cramer, F Demirkan, G Fraser, A Pristupa, NL Bartlett, MS Dilhuydy, ... Blood 128 (22), 4403-4403, 2016 | 2 | 2016 |
IBRUTINIB INCREASES THE SYSTEMIC EXPOSURE OF RITUXIMAB: PHARMACOKINETIC RESULTS FROM THE HELIOS TRIAL P Cramer, F Demirkan, G Fraser, A Pristupa, N Bartlett, M Dilhuydy, ... Hematological Oncology 35 (S2), 232-233, 2017 | 1 | 2017 |
A SIMULATION-BASED EVALUATION OF THE AREA UNDER THE EFFECT CURVE AS AN EFFICACY DRIVER FOR ANTI-INFECTIVES C Chen, L Iavarone, S Lavezzi CLINICAL PHARMACOLOGY & THERAPEUTICS 109, S9-S9, 2021 | | 2021 |
Pharmacokinetic models for drug and metabolites including first pass effects SM Lavezzi, J Zhang, P Magni, G De Nicolao, L Iavarone | | 2019 |
IV-20 Paolo Magni Evaluation of software tools for Bayesian estimation on population models: an update based on current software versions R Bartolucci, SM Lavezzi, EM Tosca, N Melillo, S Grandoni, E Borella, ... | | 2018 |
Analysis of muscular biopsy distributional data in Duchenne Muscular Dystrophy treatment: a population approach SM Lavezzi, M Rocchetti, P Bettica, S Petrini, G De Nicolao PAGE 27, 2018 | | 2018 |
Modelling of Rituximab Clearance Reduction Due to Ibrutinib Co-administration SM Lavezzi, J de Jong, M Neyens, P Cramer, F Demirkan, G Fraser, ... | | 2017 |
I-51 Italo Poggesi A Shiny App for the Probability of Technical Success of a New Molecular Entity in the Preclinical to Clinical Translational Phase SM Lavezzi, Y Cherkas, N Haddish-Berhane, S Jagannatha, ... | | 2017 |
Structural and practical identifiability of some mPBPK-TMDD models SM Lavezzi, S Zamuner, G De Nicolao, P Ma, M Simeoni PAGE 25, 2016 | | 2016 |
Methods and tools for multiscale modelling in Systems Pharmacology: a review E Borella, L Carrara, SM Lavezzi, I Massaiu, E Sauta, EM Tosca, F Vitali, ... PAGE 25, 2016 | | 2016 |
IV-23 Enrica Mezzalana Integrating Target Mediated Drug Disposition (TMDD) into a minimal physiologically based modelling framework: evaluation of different quasi-steady-state … E Mezzalana, SM Lavezzi, S Zamuner, G De Nicolao, P Ma, M Simeoni | | 2015 |
Toxicity assessment via drug-drug interaction modeling for trabectedin patients with advanced malignancies SM Lavezzi, E Mezzalana, G De Nicolao | | 2015 |