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Thorsten Maretzky
Thorsten Maretzky
Assistant Professor, Department of Internal Medicine, University of Iowa
Verified email at uiowa.edu - Homepage
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Cited by
Cited by
Year
ADAM10 mediates E-cadherin shedding and regulates epithelial cell-cell adhesion, migration, and β-catenin translocation
T Maretzky, K Reiss, A Ludwig, J Buchholz, F Scholz, E Proksch, ...
Proceedings of the National Academy of Sciences 102 (26), 9182-9187, 2005
8172005
ADAM10 cleavage of N‐cadherin and regulation of cell–cell adhesion and β‐catenin nuclear signalling
K Reiss, T Maretzky, A Ludwig, T Tousseyn, B De Strooper, D Hartmann, ...
The EMBO journal 24 (4), 742-752, 2005
6062005
iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS
DR McIlwain, PA Lang, T Maretzky, K Hamada, K Ohishi, SK Maney, ...
Science 335 (6065), 229-232, 2012
3632012
ADAM10 regulates endothelial permeability and T-Cell transmigration by proteolysis of vascular endothelial cadherin
B Schulz, J Pruessmeyer, T Maretzky, A Ludwig, CP Blobel, P Saftig, ...
Circulation research 102 (10), 1192-1201, 2008
3412008
L1 is sequentially processed by two differently activated metalloproteases and presenilin/γ-secretase and regulates neural cell adhesion, cell migration, and neurite outgrowth
T Maretzky, M Schulte, A Ludwig, S Rose-John, C Blobel, D Hartmann, ...
Molecular and cellular biology 25 (20), 9040-9053, 2005
2942005
Phytochemicals perturb membranes and promiscuously alter protein function
HI Ingólfsson, P Thakur, KF Herold, EA Hobart, NB Ramsey, X Periole, ...
ACS chemical biology 9 (8), 1788-1798, 2014
2712014
ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site
SM Le Gall, T Maretzky, PDA Issuree, XD Niu, K Reiss, P Saftig, R Khokha, ...
Journal of cell science 123 (22), 3913-3922, 2010
2542010
ADAM10 regulates FasL cell surface expression and modulates FasL-induced cytotoxicity and activation-induced cell death
M Schulte, K Reiss, M Lettau, T Maretzky, A Ludwig, D Hartmann, ...
Cell Death & Differentiation 14 (5), 1040-1049, 2007
2232007
iRHOM2 is a critical pathogenic mediator of inflammatory arthritis
PDA Issuree, T Maretzky, DR McIlwain, S Monette, X Qing, PA Lang, ...
The Journal of clinical investigation 123 (2), 928-932, 2013
1922013
iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding
T Maretzky, DR McIlwain, PDA Issuree, X Li, J Malapeira, S Amin, ...
Proceedings of the National Academy of Sciences 110 (28), 11433-11438, 2013
1782013
Phosphatidylserine exposure is required for ADAM17 sheddase function
A Sommer, F Kordowski, J Büch, T Maretzky, A Evers, J Andrä, ...
Nature communications 7 (1), 11523, 2016
1772016
Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17
T Maretzky, A Evers, W Zhou, SL Swendeman, PM Wong, S Rafii, K Reiss, ...
Nature communications 2 (1), 229, 2011
1682011
iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling
X Li, T Maretzky, G Weskamp, S Monette, X Qing, PDA Issuree, ...
Proceedings of the National Academy of Sciences 112 (19), 6080-6085, 2015
1552015
Regulated ADAM10-dependent ectodomain shedding of γ-protocadherin C3 modulates cell-cell adhesion
K Reiss, T Maretzky, IG Haas, M Schulte, A Ludwig, M Frank, P Saftig
Journal of Biological Chemistry 281 (31), 21735-21744, 2006
1392006
ADAM10-mediated E-cadherin release is regulated by proinflammatory cytokines and modulates keratinocyte cohesion in eczematous dermatitis
T Maretzky, F Scholz, B Köten, E Proksch, P Saftig, K Reiss
Journal of Investigative Dermatology 128 (7), 1737-1746, 2008
1032008
The functional maturation of a disintegrin and metalloproteinase (ADAM) 9, 10, and 17 requires processing at a newly identified proprotein convertase (PC) cleavage site
E Wong, T Maretzky, Y Peleg, CP Blobel, I Sagi
Journal of Biological Chemistry 290 (19), 12135-12146, 2015
842015
A transforming Src mutant increases the bioavailability of EGFR ligands via stimulation of the cell-surface metalloproteinase ADAM17
T Maretzky, W Zhou, XY Huang, CP Blobel
Oncogene 30 (5), 611-618, 2011
752011
Deletions in the cytoplasmic domain of iRhom1 and iRhom2 promote shedding of the TNF receptor by the protease ADAM17
SK Maney, DR McIlwain, R Polz, AA Pandyra, B Sundaram, D Wolff, ...
Science signaling 8 (401), ra109-ra109, 2015
662015
Characterization of the catalytic activity of the membrane-anchored metalloproteinase ADAM15 in cell-based assays
T Maretzky, G Yang, O Ouerfelli, CM Overall, S Worpenberg, U Hassiepen, ...
Biochemical Journal 420 (1), 105-113, 2009
662009
ADAM17 controls endochondral ossification by regulating terminal differentiation of chondrocytes
KC Hall, D Hill, M Otero, DA Plumb, D Froemel, CL Dragomir, T Maretzky, ...
Molecular and cellular biology 33 (16), 3077-3090, 2013
552013
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