The tight junction protein, occludin, regulates the directional migration of epithelial cells D Du, F Xu, L Yu, C Zhang, X Lu, H Yuan, Q Huang, F Zhang, H Bao, L Jia, ... Developmental cell 18 (1), 52-63, 2010 | 193 | 2010 |
Delivering genes across the blood-brain barrier: LY6A, a novel cellular receptor for AAV-PHP. B capsids Q Huang, KY Chan, IG Tobey, YA Chan, T Poterba, CL Boutros, ... PloS one 14 (11), e0225206, 2019 | 182 | 2019 |
Multiplexed Cre-dependent selection yields systemic AAVs for targeting distinct brain cell types S Ravindra Kumar, TF Miles, X Chen, D Brown, T Dobreva, Q Huang, ... Nature methods 17 (5), 541-550, 2020 | 142 | 2020 |
Aberrant splicing of Hugl-1 is associated with hepatocellular carcinoma progression X Lu, X Feng, X Man, G Yang, L Tang, D Du, F Zhang, H Yuan, Q Huang, ... Clinical cancer research 15 (10), 3287-3296, 2009 | 98 | 2009 |
Transcriptome-wide Landscape of Pre-mRNA Alternative Splicing Associated with Metastatic Colonization Zhi-xiang Lu, Qin Huang, Juw Won Park, Shihao Shen, Lan Lin, Collin J ... Molecular Cancer Research, molcanres. 0366.2014, 2014 | 72* | 2014 |
Loss of LARGE2 Disrupts Functional Glycosylation of α-Dystroglycan in Prostate Cancer AK Esser, MR Miller, Q Huang, MM Meier, DBV de Bernabé, CS Stipp, ... Journal of Biological Chemistry 288 (4), 2132-2142, 2013 | 38 | 2013 |
A high-efficiency AAV for endothelial cell transduction throughout the central nervous system T Krolak, KY Chan, L Kaplan, Q Huang, J Wu, Q Zheng, V Kozareva, ... Nature cardiovascular research 1 (4), 389-400, 2022 | 33 | 2022 |
A novel PHD-finger protein 14/KIF4A complex overexpressed in lung cancer is involved in cell mitosis regulation and tumorigenesis L Zhang, Q Huang, J Lou, L Zou, Y Wang, P Zhang, G Yang, J Zhang, ... Oncotarget 8 (12), 19684, 2017 | 33 | 2017 |
Depletion of PHF14, a novel histone-binding protein gene, causes neonatal lethality in mice due to respiratory failure Q Huang, L Zhang, Y Wang, C Zhang, S Zhou, G Yang, Z Li, X Gao, ... Acta Biochim Biophys Sin 45 (8), 622-633, 2013 | 29 | 2013 |
Overexpression of Csk-binding protein contributes to renal cell carcinogenesis X Feng, X Lu, X Man, W Zhou, LQ Jiang, P Knyazev, L Lei, Q Huang, ... Oncogene 28 (37), 3320-3331, 2009 | 27 | 2009 |
Targeting AAV vectors to the central nervous system by engineering capsid–receptor interactions that enable crossing of the blood–brain barrier Q Huang, AT Chen, KY Chan, H Sorensen, AJ Barry, B Azari, Q Zheng, ... PLoS Biology 21 (7), e3002112, 2023 | 16 | 2023 |
Functional characterization of the human-specific (type II) form of kallikrein 8, a gene involved in learning and memory Z Lu, Q Huang, B Su Cell Research 19 (2), 259-267, 2009 | 15 | 2009 |
Targeting AAV vectors to the CNS via de novo engineered capsid-receptor interactions Q Huang, AT Chen, KY Chan, H Sorensen, AJ Barry, B Azari, T Beddow, ... bioRxiv, 2022.10. 31.514553, 2022 | 6 | 2022 |
Systematic multi-trait AAV capsid engineering for efficient gene delivery FE Eid, AT Chen, KY Chan, Q Huang, Q Zheng, IG Tobey, S Pacouret, ... bioRxiv, 2022.12. 22.521680, 2022 | 4 | 2022 |
Aav variants with enhanced tropism DWY Sah, J Hou, K Adachi, W Wang, Q Chen, JC Soper, A Ren, XQ Ren, ... US Patent App. 17/265,749, 2021 | 2 | 2021 |
An AAV capsid reprogrammed to bind human Transferrin Receptor mediates brain-wide gene delivery Q Huang, KY Chan, S Lou, C Keyes, J Wu, NR Botticello-Romero, ... bioRxiv, 2023.12. 20.572615, 2023 | 1 | 2023 |
AAV DNA library generation SR Kumar, TF Shay, X Chen, D Brown, T Dobreva, Q Huang, X Ding, ... | | 2023 |
Cloning individual AAV capsid variants SR Kumar, TF Shay, X Chen, D Brown, T Dobreva, Q Huang, X Ding, ... | | 2023 |
Library tissue handling, viral DNA extraction, and NGS sample preparation M Chuapoco, SR Kumar, TF Shay, X Chen, D Brown, T Dobreva, ... | | 2023 |
Aav variants with enhanced tropism DWY Sah, J Hou, K Adachi, W Wang, Q Chen, JC Soper, A Ren, XQ Ren, ... US Patent App. 17/631,737, 2022 | | 2022 |