A single nucleotide polymorphism in the MDM2 promoter attenuates the p53 tumor suppressor pathway and accelerates tumor formation in humans GL Bond, W Hu, EE Bond, H Robins, SG Lutzker, NC Arva, J Bargonetti, ... Cell 119 (5), 591-602, 2004 | 1473 | 2004 |
Mutant p53 disrupts mammary tissue architecture via the mevalonate pathway WA Freed-Pastor, H Mizuno, X Zhao, A Langerød, SH Moon, ... Cell 148 (1), 244-258, 2012 | 889 | 2012 |
Wild-type p53 activates transcription in vitro G Farmer, J Bargonetti, H Zhu, P Friedman, R Prywes, C Prives Nature 358 (6381), 83-86, 1992 | 799 | 1992 |
Multiple roles of the tumor suppressor p53 J Bargonetti, JJ Manfredi Current opinion in oncology 14 (1), 86-91, 2002 | 506 | 2002 |
Wild-type but not mutant p53 immunopurified proteins bind to sequences adjacent to the SV40 origin of replication J Bargonetti, PN Friedman, SE Kern, B Vogelstein, C Prives Cell 65 (6), 1083-1091, 1991 | 500 | 1991 |
Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element. GP Zambetti, J Bargonetti, K Walker, C Prives, AJ Levine Genes & development 6 (7), 1143-1152, 1992 | 471 | 1992 |
The p53 protein is an unusually shaped tetramer that binds directly to DNA. PN Friedman, X Chen, J Bargonetti, C Prives Proceedings of the National Academy of Sciences 90 (8), 3319-3323, 1993 | 413 | 1993 |
A proteolytic fragment from the central region of p53 has marked sequence-specific DNA-binding activity when generated from wild-type but not from oncogenic mutant p53 protein. J Bargonetti, JJ Manfredi, X Chen, DR Marshak, C Prives Genes & development 7 (12b), 2565-2574, 1993 | 406 | 1993 |
Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53. J Bargonetti, I Reynisdottir, PN Friedman, C Prives Genes & development 6 (10), 1886-1898, 1992 | 346 | 1992 |
Mutant p53 in MDA-MB-231 breast cancer cells is stabilized by elevated phospholipase D activity and contributes to survival signals generated by phospholipase D L Hui, Y Zheng, Y Yan, J Bargonetti, DA Foster Oncogene 25 (55), 7305-7310, 2006 | 250 | 2006 |
p53, through p21 (WAF1/CIP1), induces cyclin D1 synthesis X Chen, J Bargonetti, C Prives Cancer Research 55 (19), 4257-4263, 1995 | 237 | 1995 |
Infrared spectroscopy of human tissue. V. Infrared spectroscopic studies of myeloid leukemia (ML‐1) cells at different phases of the cell cycle S Boydston‐White, T Gopen, S Houser, J Bargonetti, M Diem Biospectroscopy 5 (4), 219-227, 1999 | 230 | 1999 |
A chromatin-associated and transcriptionally inactive p53-Mdm2 complex occurs in mdm2 SNP309 homozygous cells NC Arva, TR Gopen, KE Talbott, LE Campbell, A Chicas, DE White, ... Journal of Biological Chemistry 280 (29), 26776-26787, 2005 | 152 | 2005 |
Mutant p53 cooperates with the SWI/SNF chromatin remodeling complex to regulate VEGFR2 in breast cancer cells NT Pfister, V Fomin, K Regunath, JY Zhou, W Zhou, L Silwal-Pandit, ... Genes & development 29 (12), 1298-1315, 2015 | 148 | 2015 |
Dietary downregulation of mutant p53 levels via glucose restriction: mechanisms and implications for tumor therapy OC Rodriguez, S Choudhury, V Kolukula, EE Vietsch, J Catania, A Preet, ... Cell cycle 11 (23), 4436-4446, 2012 | 140 | 2012 |
Initiation of rolling-circle replication in pT181 plasmid: initiator protein enhances cruciform extrusion at the origin. P Noirot, J Bargonetti, RP Novick Proceedings of the National Academy of Sciences 87 (21), 8560-8564, 1990 | 117 | 1990 |
Proteome-wide analysis of mutant p53 targets in breast cancer identifies new levels of gain-of-function that influence PARP, PCNA, and MCM4 A Polotskaia, G Xiao, K Reynoso, C Martin, WG Qiu, RC Hendrickson, ... Proceedings of the National Academy of Sciences 112 (11), E1220-E1229, 2015 | 110 | 2015 |
A p53-independent role of Mdm2 in estrogen-mediated activation of breast cancer cell proliferation A Brekman, KE Singh, A Polotskaia, N Kundu, J Bargonetti Breast Cancer Research 13, 1-14, 2011 | 99 | 2011 |
p53 represses Sp1 DNA binding and HIV-LTR directed transcription. J Bargonetti, A Chicas, D White, C Prives Cellular and molecular biology (Noisy-le-Grand, France) 43 (7), 935-949, 1997 | 95 | 1997 |
Inhibition of human p53 basal transcription by down-regulation of protein kinase Cδ T Abbas, D White, L Hui, K Yoshida, DA Foster, J Bargonetti Journal of Biological Chemistry 279 (11), 9970-9977, 2004 | 88 | 2004 |