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Jonathan D Kiefer
Jonathan D Kiefer
Email verificata su ethz.ch
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Anno
An engineered protein antagonist of K-Ras/B-Raf interaction
MJ Kauke, MW Traxlmayr, JA Parker, JD Kiefer, R Knihtila, J McGee, ...
Scientific reports 7 (1), 5831, 2017
662017
Strong enrichment of aromatic residues in binding sites from a charge-neutralized hyperthermostable Sso7d scaffold library
MW Traxlmayr, JD Kiefer, RR Srinivas, E Lobner, AW Tisdale, NK Mehta, ...
Journal of Biological Chemistry 291 (43), 22496-22508, 2016
622016
Anti-human CD117 CAR T-cells efficiently eliminate healthy and malignant CD117-expressing hematopoietic cells
R Myburgh, JD Kiefer, NF Russkamp, CF Magnani, N Nuñez, A Simonis, ...
Leukemia 34 (10), 2688-2703, 2020
612020
Immunocytokines and bispecific antibodies: two complementary strategies for the selective activation of immune cells at the tumor site
JD Kiefer, D Neri
Immunological reviews 270 (1), 178-192, 2016
482016
Quantitative and qualitative analysis of humoral immunity reveals continued and personalized evolution in chronic viral infection
NJ Kräutler, A Yermanos, A Pedrioli, SPM Welten, D Lorgé, U Greczmiel, ...
Cell reports 30 (4), 997-1012. e6, 2020
342020
Anti-CD117 immunotherapy to eliminate hematopoietic and leukemia stem cells
NF Russkamp, R Myburgh, JD Kiefer, D Neri, MG Manz
Experimental Hematology 95, 31-45, 2021
172021
Targeted delivery of TNF potentiates the antibody-dependent cell-mediated cytotoxicity of an anti-melanoma immunoglobulin
P Murer, JD Kiefer, L Plüss, M Matasci, SL Blümich, M Stringhini, D Neri
Journal of Investigative Dermatology 139 (6), 1339-1348, 2019
152019
Design principles for SuCESsFul biosensors: Specific fluorophore/analyte binding and minimization of fluorophore/scaffold interactions
S De Picciotto, PM Dickson, MW Traxlmayr, BS Marques, E Socher, ...
Journal of molecular biology 428 (20), 4228-4241, 2016
152016
A Fibrin-Specific Monoclonal Antibody from a Designed Phage Display Library Inhibits Clot Formation and Localizes to Tumors In Vivo
A Putelli, JD Kiefer, M Zadory, M Matasci, D Neri
Journal of molecular biology 426 (21), 3606-3618, 2014
152014
Structures of designed armadillo repeat proteins binding to peptides fused to globular domains
S Hansen, JD Kiefer, C Madhurantakam, PRE Mittl, A Plückthun
Protein Science 26 (10), 1942-1952, 2017
132017
Generation of “LYmph Node Derived Antibody Libraries”(LYNDAL) for selecting fully human antibody fragments with therapeutic potential
P Diebolder, A Keller, S Haase, A Schlegelmilch, JD Kiefer, T Karimi, ...
MAbs 6 (1), 130-142, 2014
132014
Anti-human CD117 CAR T-cells efficiently eliminate hematopoietic stem and CD117-positive AML cells
R Myburgh, J Kiefer, NF Russkamp, A Simonis, S Pfister, CM Wilk, ...
Blood 132, 4063, 2018
42018
A bispecific antibody targeting CD117 and CD3 enables T cell mediated killing of CD117-expressing healthy and malignant hematopoietic cells
JD Kiefer, R Myburgh, NF Russkamp, L Volta, A Guggisberg, ...
Blood 138, 2354, 2021
12021
BISPECIFIC BINDING AGENT THAT BINDS TO CD117/c-KIT AND CD3
J Kiefer, R Myburgh, M Manz, D Neri
US Patent App. 17/640,412, 2022
2022
Bispecific binding agent that binds to CD117/c-KIT and CD3
J KIEFER, R MYBURGH, M Manz, D Neri
2021
Treating Acute Myeloid Leukemia with Novel Antibody-Based Therapies
JD Kiefer
ETH Zurich, 2019
2019
Generation of mouse CAR T-cells for the depletion of cKIT-positive hematopoietic cells
N Russkamp, R Myburgh, J Kiefer, D Neri, M Manz
SWISS MEDICAL WEEKLY 148, 23S-23S, 2018
2018
Il sistema al momento non può eseguire l'operazione. Riprova più tardi.
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