|Haploinsufficiency of the autism-associated Shank3 gene leads to deficits in synaptic function, social interaction, and social communication|
O Bozdagi, T Sakurai, D Papapetrou, X Wang, DL Dickstein, N Takahashi, ...
Molecular autism 1 (1), 15, 2010
|Identification of small exonic CNV from whole-exome sequence data and application to autism spectrum disorder|
CS Poultney, AP Goldberg, E Drapeau, Y Kou, H Harony-Nicolas, ...
The American Journal of Human Genetics 93 (4), 607-619, 2013
|Autism-like deficits in Shank3-deficient mice are rescued by targeting actin regulators|
LJ Duffney, P Zhong, J Wei, E Matas, J Cheng, L Qin, K Ma, DM Dietz, ...
Cell reports 11 (9), 1400-1413, 2015
|Molecular dissection of NRG1-ERBB4 signaling implicates PTPRZ1 as a potential schizophrenia susceptibility gene|
JD Buxbaum, L Georgieva, JJ Young, C Plescia, Y Kajiwara, Y Jiang, ...
Molecular psychiatry 13 (2), 162, 2008
|A critical role for human caspase-4 in endotoxin sensitivity|
Y Kajiwara, T Schiff, G Voloudakis, MAG Sosa, G Elder, O Bozdagi, ...
The Journal of Immunology 193 (1), 335-343, 2014
|Integrative network analysis of nineteen brain regions identifies molecular signatures and networks underlying selective regional vulnerability to Alzheimer’s disease|
M Wang, P Roussos, A McKenzie, X Zhou, Y Kajiwara, KJ Brennand, ...
Genome medicine 8 (1), 104, 2016
|Canonical inflammasomes drive IFN-γ to prime caspase-11 in defense against a cytosol-invasive bacterium|
Y Aachoui, Y Kajiwara, IA Leaf, D Mao, JPY Ting, J Coers, A Aderem, ...
Cell host & microbe 18 (3), 320-332, 2015
|SLITRK1 binds 14-3-3 and regulates neurite outgrowth in a phosphorylation-dependent manner|
Y Kajiwara, JD Buxbaum, DE Grice
Biological psychiatry 66 (10), 918-925, 2009
|FE65 binds Teashirt, inhibiting expression of the primate-specific caspase-4|
Y Kajiwara, A Akram, P Katsel, V Haroutunian, J Schmeidler, G Beecham, ...
PLoS One 4 (4), e5071, 2009
|cGAS drives noncanonical-inflammasome activation in age-related macular degeneration|
N Kerur, S Fukuda, D Banerjee, Y Kim, D Fu, I Apicella, A Varshney, ...
Nature medicine 24 (1), 50, 2018
|Phenotypic and functional analysis of SHANK3 stop mutations identified in individuals with ASD and/or ID|
DM Cochoy, A Kolevzon, Y Kajiwara, M Schoen, M Pascual-Lucas, ...
Molecular autism 6 (1), 23, 2015
|Characterization of SLITRK1 variation in obsessive-compulsive disorder|
U Ozomaro, G Cai, Y Kajiwara, S Yoon, V Makarov, R Delorme, ...
PloS one 8 (8), e70376, 2013
|Analysis of a purported SHANK3 mutation in a boy with autism: clinical impact of rare variant research in neurodevelopmental disabilities|
A Kolevzon, G Cai, L Soorya, N Takahashi, D Grodberg, Y Kajiwara, ...
Brain research 1380, 98-105, 2011
|Calsenilin interacts with transcriptional co‐repressor C‐terminal binding protein (s)|
NF Zaidi, KG Kuplast, KJ Washicosky, Y Kajiwara, JD Buxbaum, W Wasco
Journal of neurochemistry 98 (4), 1290-1301, 2006
|The bZIP-like motif of hnRNP C directs the nuclear accumulation of pre-mRNA and lethality in yeast|
J Tan, Y Kajiwara, L Shahied, J Li, JG McAfee, WM LeStourgeon
Journal of molecular biology 305 (4), 829-838, 2001
|Extensive proteomic screening identifies the obesity-related NYGGF4 protein as a novel LRP1-interactor, showing reduced expression in early Alzheimer's disease|
Y Kajiwara, S Franciosi, N Takahashi, L Krug, J Schmeidler, K Taddei, ...
Molecular neurodegeneration 5 (1), 1, 2010
|Compound heterozygous PNPLA6 mutations cause Boucher–Neuhäuser syndrome with late-onset ataxia|
A Deik, B Johannes, JC Rucker, E Sanchez, SE Brodie, E Deegan, ...
Journal of neurology 261 (12), 2411-2423, 2014
|Presenilin 1 is necessary for neuronal, but not glial, EGFR expression and neuroprotection via γ-secretase-independent transcriptional mechanisms|
J Bruban, G Voloudakis, Q Huang, Y Kajiwara, M Al Rahim, Y Yoon, ...
The FASEB Journal 29 (9), 3702-3712, 2015
|The human-specific CASP4 gene product contributes to Alzheimer-related synaptic and behavioural deficits|
Y Kajiwara, A McKenzie, N Dorr, MA Gama Sosa, G Elder, J Schmeidler, ...
Human molecular genetics 25 (19), 4315-4327, 2016
|GJA1 (connexin43) is a key regulator of Alzheimer’s disease pathogenesis|
Y Kajiwara, E Wang, M Wang, WC Sin, KJ Brennand, E Schadt, CC Naus, ...
Acta neuropathologica communications 6 (1), 144, 2018