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Liya Hu
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Cell attachment protein VP8* of a human rotavirus specifically interacts with A-type histo-blood group antigen
L Hu, SE Crawford, R Czako, NW Cortes-Penfield, DF Smith, J Le Pendu, ...
Nature 485 (7397), 256-259, 2012
3712012
Human milk oligosaccharides, milk microbiome and infant gut microbiome modulate neonatal rotavirus infection
S Ramani, CJ Stewart, DR Laucirica, NJ Ajami, B Robertson, CA Autran, ...
Nature communications 9 (1), 5010, 2018
1552018
Rotavirus non-structural proteins: structure and function
L Hu, SE Crawford, JM Hyser, MK Estes, BVV Prasad
Current opinion in virology 2 (4), 380-388, 2012
1382012
Human milk contains novel glycans that are potential decoy receptors for neonatal rotaviruses
Y Yu, Y Lasanajak, X Song, L Hu, S Ramani, ML Mickum, DJ Ashline, ...
Molecular & cellular proteomics 13 (11), 2944-2960, 2014
1262014
The VP8* domain of neonatal rotavirus strain G10P [11] binds to type II precursor glycans
S Ramani, NW Cortes-Penfield, L Hu, SE Crawford, R Czako, DF Smith, ...
Journal of virology 87 (13), 7255-7264, 2013
1022013
Diversity in rotavirus–host glycan interactions: a “sweet” spectrum
S Ramani, L Hu, BVV Prasad, MK Estes
Cellular and molecular gastroenterology and hepatology 2 (3), 263-273, 2016
922016
Structure and mechanism of human diacylglycerol O-acyltransferase 1
L Wang, H Qian, Y Nian, Y Han, Z Ren, H Zhang, L Hu, BVV Prasad, ...
Nature 581 (7808), 329-332, 2020
822020
Differential active site requirements for NDM-1 β-lactamase hydrolysis of carbapenem versus penicillin and cephalosporin antibiotics
Z Sun, L Hu, B Sankaran, BVV Prasad, T Palzkill
Nature communications 9 (1), 4524, 2018
792018
A novel form of rotavirus NSP2 and phosphorylation-dependent NSP2-NSP5 interactions are associated with viroplasm assembly
JM Criglar, L Hu, SE Crawford, JM Hyser, JR Broughman, BVV Prasad, ...
Journal of Virology 88 (2), 786-798, 2014
742014
Structural characterization by multistage mass spectrometry (MSn) of human milk glycans recognized by human rotaviruses
DJ Ashline, Y Yu, Y Lasanajak, X Song, L Hu, S Ramani, V Prasad, ...
Molecular & Cellular Proteomics 13 (11), 2961-2974, 2014
732014
Glycan recognition in globally dominant human rotaviruses
L Hu, B Sankaran, DR Laucirica, K Patil, W Salmen, ACM Ferreon, ...
Nature communications 9 (1), 2631, 2018
672018
A triple mutant in the Ω-loop of TEM-1 β-lactamase changes the substrate profile via a large conformational change and an altered general base for catalysis
V Stojanoski, DC Chow, L Hu, B Sankaran, HF Gilbert, BVV Prasad, ...
Journal of Biological Chemistry 290 (16), 10382-10394, 2015
642015
Structural basis of glycan specificity in neonate-specific bovine-human reassortant rotavirus
L Hu, S Ramani, R Czako, B Sankaran, Y Yu, DF Smith, RD Cummings, ...
Nature communications 6 (1), 8346, 2015
562015
Structural basis for different substrate profiles of two closely related class D β-lactamases and their inhibition by halogens
V Stojanoski, DC Chow, B Fryszczyn, L Hu, P Nordmann, L Poirel, ...
Biochemistry 54 (21), 3370-3380, 2015
452015
Phosphorylation cascade regulates the formation and maturation of rotaviral replication factories
JM Criglar, R Anish, L Hu, SE Crawford, B Sankaran, BVV Prasad, ...
Proceedings of the National Academy of Sciences 115 (51), E12015-E12023, 2018
422018
Structural basis of glycan interaction in gastroenteric viral pathogens
BVV Prasad, S Shanker, L Hu, JM Choi, SE Crawford, S Ramani, R Czako, ...
Current opinion in virology 7, 119-127, 2014
412014
Structural features of glycan recognition among viral pathogens
S Shanker, L Hu, S Ramani, RL Atmar, MK Estes, BVV Prasad
Current opinion in structural biology 44, 211-218, 2017
392017
Human VP8* mAbs neutralize rotavirus selectively in human intestinal epithelial cells
N Feng, L Hu, S Ding, M Sanyal, B Zhao, B Sankaran, S Ramani, ...
The Journal of clinical investigation 129 (9), 3839-3851, 2019
362019
Structural basis for 2′-5′-oligoadenylate binding and enzyme activity of a viral RNase L antagonist
KM Ogden, L Hu, BK Jha, B Sankaran, SR Weiss, RH Silverman, ...
Journal of virology 89 (13), 6633-6645, 2015
342015
Identifying oxacillinase-48 carbapenemase inhibitors using DNA-encoded chemical libraries
DM Taylor, J Anglin, S Park, MN Ucisik, JC Faver, N Simmons, Z Jin, ...
ACS infectious diseases 6 (5), 1214-1227, 2020
322020
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