Applications of phospholipid bilayer nanodiscs in the study of membranes and membrane proteins A Nath, WM Atkins, SG Sligar Biochemistry 46 (8), 2059-2069, 2007 | 538 | 2007 |
Protein-induced photophysical changes to the amyloid indicator dye thioflavin T LS Wolfe, MF Calabrese, A Nath, DV Blaho, AD Miranker, Y Xiong Proceedings of the National Academy of Sciences 107 (39), 16863-16868, 2010 | 377 | 2010 |
The conformational ensembles of α-synuclein and tau: Combining single-molecule FRET and simulations A Nath, M Sammalkorpi, DC DeWitt, AJ Trexler, S Elbaum-Garfinkle, ... Biophysical journal 103 (9), 1940-1949, 2012 | 141 | 2012 |
A quantitative index of substrate promiscuity A Nath, WM Atkins Biochemistry 47 (1), 157-166, 2008 | 104 | 2008 |
Ligand Binding to Cytochrome P450 3A4 in Phospholipid Bilayer Nanodiscs THE EFFECT OF MODEL MEMBRANES A Nath, YV Grinkova, SG Sligar, WM Atkins Journal of Biological Chemistry 282 (39), 28309-28320, 2007 | 93 | 2007 |
HspB1 and Hsc70 chaperones engage distinct tau species and have different inhibitory effects on amyloid formation HER Baughman, AF Clouser, RE Klevit, A Nath Journal of Biological Chemistry 293 (8), 2687-2700, 2018 | 88 | 2018 |
Functional promiscuity correlates with conformational heterogeneity in A-class glutathione S-transferases L Hou, MT Honaker, LM Shireman, LM Balogh, AG Roberts, K Ng, A Nath, ... Journal of biological chemistry 282 (32), 23264-23274, 2007 | 87 | 2007 |
A theoretical validation of the substrate depletion approach to determining kinetic parameters A Nath, WM Atkins Drug metabolism and disposition 34 (9), 1433-1435, 2006 | 76 | 2006 |
Single-molecule fluorescence spectroscopy using phospholipid bilayer nanodiscs A Nath, AJ Trexler, P Koo, AD Miranker, WM Atkins, E Rhoades Methods in enzymology 472, 89-117, 2010 | 66 | 2010 |
A functional role for intrinsic disorder in the tau-tubulin complex AM Melo, J Coraor, S Elbaum-Garfinkle, A Nath, E Rhoades Proceedings of the National Academy of Sciences 113 (50), 14336-14341, 2016 | 64 | 2016 |
A conformational transition observed in single HIV-1 Gag molecules during in vitro assembly of virus-like particles JB Munro, A Nath, M Färber, SAK Datta, A Rein, E Rhoades, W Mothes Journal of virology 88 (6), 3577-3585, 2014 | 61 | 2014 |
Quantitative Characterization of the Interactions among c-myc Transcriptional Regulators FUSE, FBP, and FIR H Hsiao, A Nath, CY Lin, EJ Folta-Stogniew, E Rhoades, DT Braddock Biochemistry 49 (22), 4620-4634, 2010 | 60 | 2010 |
Interplay of disordered and ordered regions of a human small heat shock protein yields an ensemble of" quasi-ordered" states. AF Clouser, HER Baughman, B Basanta, M Guttman, A Nath, RE Klevit bioRxiv, 750646, 2019 | 47 | 2019 |
A membrane‐bound antiparallel dimer of rat islet amyloid polypeptide A Nath, AD Miranker, E Rhoades Angewandte Chemie International Edition 50 (46), 10859-10862, 2011 | 47 | 2011 |
Allosteric effects on substrate dissociation from cytochrome P450 3A4 in nanodiscs observed by ensemble and single-molecule fluorescence spectroscopy A Nath, PK Koo, E Rhoades, WM Atkins Journal of the American Chemical Society 130 (47), 15746-15747, 2008 | 46 | 2008 |
Nile Red is a fluorescent allosteric substrate of cytochrome P450 3A4 JN Lampe, C Fernandez, A Nath, WM Atkins Biochemistry 47 (2), 509-516, 2008 | 43 | 2008 |
Expression and functional characterization of breast cancer-associated cytochrome P450 4Z1 in Saccharomyces cerevisiae MG McDonald, S Ray, CJ Amorosi, KA Sitko, JP Kowalski, L Paco, A Nath, ... Drug Metabolism and Disposition 45 (12), 1364-1371, 2017 | 39 | 2017 |
In vitro to in vivo extrapolation of the complex drug-drug interaction of bupropion and its metabolites with CYP2D6; simultaneous reversible inhibition and CYP2D6 downregulation JE Sager, S Tripathy, LSL Price, A Nath, J Chang, A Stephenson-Famy, ... Biochemical pharmacology 123, 85-96, 2017 | 34 | 2017 |
CYP26C1 is a hydroxylase of multiple active retinoids and interacts with cellular retinoic acid binding proteins G Zhong, D Ortiz, A Zelter, A Nath, N Isoherranen Molecular pharmacology 93 (5), 489-503, 2018 | 33 | 2018 |
The Rational Discovery of a Tau Aggregation Inhibitor DW Baggett, A Nath Biochemistry 57 (42), 6099-6107, 2018 | 32 | 2018 |